Comparing BWI76_RS16695 FitnessBrowser__Koxy:BWI76_RS16695 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P0AAH4 Putrescine export system ATP-binding protein SapD from Escherichia coli (strain K12) (see paper)
38% identity, 96% coverage: 5:318/326 of query aligns to 3:323/330 of P0AAH4
Q8RDH4 Dipeptide transport ATP-binding protein DppD; EC 7.4.2.9 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
34% identity, 97% coverage: 5:320/326 of query aligns to 4:321/326 of Q8RDH4
4fwiB Crystal structure of the nucleotide-binding domain of a dipeptide abc transporter (see paper)
34% identity, 97% coverage: 5:320/326 of query aligns to 3:310/310 of 4fwiB
7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp (see paper)
36% identity, 78% coverage: 5:259/326 of query aligns to 3:246/250 of 7z18I
7z15I E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
36% identity, 78% coverage: 5:259/326 of query aligns to 3:246/253 of 7z15I
7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation (see paper)
35% identity, 78% coverage: 5:259/326 of query aligns to 3:246/250 of 7z16I
P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 3 papers)
34% identity, 83% coverage: 5:274/326 of query aligns to 1:261/343 of P30750
Sites not aligning to the query:
6cvlD Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
33% identity, 83% coverage: 5:274/326 of query aligns to 2:262/344 of 6cvlD
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form (see paper)
33% identity, 83% coverage: 5:274/326 of query aligns to 2:262/344 of 3tuzC
Sites not aligning to the query:
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form (see paper)
33% identity, 83% coverage: 5:274/326 of query aligns to 2:262/344 of 3tuiC
3c4jA Abc protein artp in complex with atp-gamma-s
33% identity, 78% coverage: 5:259/326 of query aligns to 3:240/242 of 3c4jA
3c41J Abc protein artp in complex with amp-pnp/mg2+
33% identity, 78% coverage: 5:259/326 of query aligns to 3:240/242 of 3c41J
2olkA Abc protein artp in complex with adp-beta-s
33% identity, 78% coverage: 5:259/326 of query aligns to 3:240/242 of 2olkA
2oljA Abc protein artp in complex with adp/mg2+
33% identity, 78% coverage: 5:259/326 of query aligns to 3:240/242 of 2oljA
4u00A Crystal structure of ttha1159 in complex with adp (see paper)
32% identity, 71% coverage: 28:257/326 of query aligns to 21:236/241 of 4u00A
Sites not aligning to the query:
P75957 Lipoprotein-releasing system ATP-binding protein LolD; EC 7.6.2.- from Escherichia coli (strain K12) (see paper)
32% identity, 73% coverage: 1:238/326 of query aligns to 1:226/233 of P75957
7arlD Lolcde in complex with lipoprotein and adp (see paper)
35% identity, 65% coverage: 25:236/326 of query aligns to 22:221/222 of 7arlD
7mdyC Lolcde nucleotide-bound
35% identity, 66% coverage: 25:238/326 of query aligns to 22:223/226 of 7mdyC
Sites not aligning to the query:
7v8iD Lolcd(e171q)e with bound amppnp in nanodiscs (see paper)
32% identity, 73% coverage: 2:238/326 of query aligns to 1:225/229 of 7v8iD
4ymuJ Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
29% identity, 78% coverage: 5:259/326 of query aligns to 1:238/240 of 4ymuJ
>BWI76_RS16695 FitnessBrowser__Koxy:BWI76_RS16695
MSRALITFNQLSVSFAADKSRVRAVQEVSFTIRAGQTVGVVGESGCGKSVTALSLMGLLP
PQAARIDGGEILFAGQDLLRLKNAHMADLRGNQLAMIFQEPMSALNPVLTVGEQLCEPLI
RHRGESPKLAWQHAIQLLADVGLARADSLMASYPHQLSGGMLQRVMIAMALSCQPKLLIA
DEPTTALDVTVQAQILRLLRDQARANRMAMMLITHDLGVIAQMAEHVVVMYAGRIVEQGA
TADILRNPQHPYTQGLIASRPVPGERRRRLYSIPGQVPDLAALPVGCAFAERCANATVRC
RQGVPPLVGQTQQAACFYSELAESVV
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory