Comparing BWI76_RS17220 FitnessBrowser__Koxy:BWI76_RS17220 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
Q8RDH4 Dipeptide transport ATP-binding protein DppD; EC 7.4.2.9 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
36% identity, 92% coverage: 10:316/334 of query aligns to 3:303/326 of Q8RDH4
Sites not aligning to the query:
4fwiB Crystal structure of the nucleotide-binding domain of a dipeptide abc transporter (see paper)
35% identity, 92% coverage: 10:316/334 of query aligns to 2:292/310 of 4fwiB
Sites not aligning to the query:
P0AAH4 Putrescine export system ATP-binding protein SapD from Escherichia coli (strain K12) (see paper)
34% identity, 95% coverage: 11:328/334 of query aligns to 3:321/330 of P0AAH4
7z15I E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
37% identity, 69% coverage: 38:268/334 of query aligns to 17:247/253 of 7z15I
Sites not aligning to the query:
7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp (see paper)
37% identity, 69% coverage: 38:268/334 of query aligns to 17:247/250 of 7z18I
Sites not aligning to the query:
7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation (see paper)
37% identity, 69% coverage: 38:268/334 of query aligns to 17:247/250 of 7z16I
Sites not aligning to the query:
2d62A Crystal structure of multiple sugar binding transport atp- binding protein
36% identity, 72% coverage: 31:270/334 of query aligns to 13:248/375 of 2d62A
P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 3 papers)
35% identity, 74% coverage: 30:277/334 of query aligns to 11:256/343 of P30750
Sites not aligning to the query:
6cvlD Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
35% identity, 74% coverage: 30:277/334 of query aligns to 12:257/344 of 6cvlD
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form (see paper)
35% identity, 74% coverage: 30:277/334 of query aligns to 12:257/344 of 3tuzC
Sites not aligning to the query:
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form (see paper)
35% identity, 74% coverage: 30:277/334 of query aligns to 12:257/344 of 3tuiC
1g291 Malk (see paper)
34% identity, 72% coverage: 31:270/334 of query aligns to 10:245/372 of 1g291
Sites not aligning to the query:
3c4jA Abc protein artp in complex with atp-gamma-s
35% identity, 70% coverage: 36:268/334 of query aligns to 15:241/242 of 3c4jA
Sites not aligning to the query:
3c41J Abc protein artp in complex with amp-pnp/mg2+
35% identity, 70% coverage: 36:268/334 of query aligns to 15:241/242 of 3c41J
Sites not aligning to the query:
2olkA Abc protein artp in complex with adp-beta-s
35% identity, 70% coverage: 36:268/334 of query aligns to 15:241/242 of 2olkA
Sites not aligning to the query:
2oljA Abc protein artp in complex with adp/mg2+
35% identity, 70% coverage: 36:268/334 of query aligns to 15:241/242 of 2oljA
Sites not aligning to the query:
4u00A Crystal structure of ttha1159 in complex with adp (see paper)
33% identity, 74% coverage: 23:268/334 of query aligns to 5:239/241 of 4u00A
4ymuJ Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
34% identity, 71% coverage: 31:268/334 of query aligns to 8:239/240 of 4ymuJ
P9WQI3 Trehalose import ATP-binding protein SugC; MtbSugC; Nucleotide-binding domain of SugABC transporter; NBD of SugABC transporter; SugABC transporter ATPase SugC; EC 7.5.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
34% identity, 69% coverage: 39:267/334 of query aligns to 19:237/393 of P9WQI3
1vciA Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
32% identity, 69% coverage: 36:267/334 of query aligns to 18:231/353 of 1vciA
Sites not aligning to the query:
>BWI76_RS17220 FitnessBrowser__Koxy:BWI76_RS17220
MNAVTEQRKVLLEIADLKVHFDIKDGKQWFWQPSKTLKAVDGVTLRLYEGETLGVVGESG
CGKSTFARAIIGLVKATDGKVAWLGKDLLGMKADEWRDVRSDIQMIFQDPLASLNPRMTI
GEIIAEPLRTYHPKMPRQEVRDRVKAMMMKVGLLPNLINRYPHEFSGGQCQRIGIARALI
LEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYL
GHAVELGTYDEVYHNPLHPYTKALMSAVPVPDPDKEKNKTIQLLEGELPSPINPPSGCVF
RTRCPIAGPECAKTRPVLEGSFRHAVSCLKVDPL
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory