Comparing BWI76_RS18690 FitnessBrowser__Koxy:BWI76_RS18690 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
P69786 PTS system glucose-specific EIICB component; EIICB-Glc; EII-Glc; EC 2.7.1.199 from Escherichia coli (strain K12) (see 5 papers)
28% identity, 99% coverage: 6:510/511 of query aligns to 8:477/477 of P69786
P09323 PTS system N-acetylglucosamine-specific EIICBA component; EIICBA-Nag; EII-Nag; EC 2.7.1.193 from Escherichia coli (strain K12) (see paper)
32% identity, 73% coverage: 132:505/511 of query aligns to 94:464/648 of P09323
Sites not aligning to the query:
6bvgA Crystal structure of bcmalt t280c-e54c crosslinked by divalent mercury (see paper)
28% identity, 80% coverage: 8:414/511 of query aligns to 6:442/447 of 6bvgA
1o2fB Complex of enzyme iiaglc and iibglc phosphocarrier protein hpr from escherichia coli nmr, restrained regularized mean structure (see paper)
34% identity, 14% coverage: 438:507/511 of query aligns to 6:75/77 of 1o2fB
>BWI76_RS18690 FitnessBrowser__Koxy:BWI76_RS18690
MIGVKKLQDFSKAMIGPVLYLPVIGLLIALLSMTTNKIWLAEDSSLYLLGKYVSSMLWAV
MNNLGFFFCLGLAGGLAKTRKAEAAFVAAMTWFMYLAANNSWLTLTQRLAAGASNAQLYG
SGQTYIFGFQVIDMGVFLGIILGCAVAFIHNRFVEIEFRGAFSIYGNSKLVLIIMIPLVG
VFAIATVYVWPIVEHGISALTGVMKTFGAAGVFLYGFLNRFLIPTGLHHLIWSPFVFTSI
GGQLLIDGQTVVGAKPIFLAEIANNTGAALSDSARFLTYGMVKIFGTAGMALAFYKTARP
ENKQKLKITLIPLIVTSFLVGITEPFEFLFIFTAPLLWLVYSLLDGFFQMLAWLLDVRVC
ATNGIIDFIVYNIPAGAHLTRWPVFVALGLMETAAMYYVGKFMIIHFKMPTPGQEQEVAV
VNQPPSAGSPDAASGEQVILGLGGKENVCSVDNCFTRLRVDVRDPALIQEHILKTSGGTS
VIIKGHHVQVIYGLGVNKIRNAVNRYLDVHE
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory