Comparing BWI76_RS18955 FitnessBrowser__Koxy:BWI76_RS18955 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
6j2lA Crystal structure of bi-functional enzyme (see paper)
88% identity, 97% coverage: 5:197/199 of query aligns to 8:200/200 of 6j2lA
6j2lB Crystal structure of bi-functional enzyme (see paper)
81% identity, 97% coverage: 5:197/199 of query aligns to 7:185/185 of 6j2lB
7bgnA Crystal structure of mthisn2-amp complex, a bifunctional enzyme from the histidine biosynthetic pathway (see paper)
38% identity, 93% coverage: 13:197/199 of query aligns to 15:203/204 of 7bgnA
Sites not aligning to the query:
7bgmA Crystal structure of mthisn2, a bifunctional enzyme from the histidine biosynthetic pathway (see paper)
36% identity, 93% coverage: 13:197/199 of query aligns to 17:212/213 of 7bgmA
>BWI76_RS18955 FitnessBrowser__Koxy:BWI76_RS18955
MLSEQLDWQKTDGLMPVIVQHAVSGEVLMLGYMNQDALAKTEETGKVTFYSRTKQRLWTK
GETSGNFLNVVSITPDCDNDTLLALVNPIGPTCHKGTSSCFGETGHQWLFLYQLEQLLAE
RKHADPESSYTAKLYASGTKRIAQKVGEEGVETALAATVHDQFELKNEASDLMYHLLVLL
QDQGLNLTDVVENLRSRHK
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory