Comparing BWI76_RS19190 FitnessBrowser__Koxy:BWI76_RS19190 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q8RDH4 Dipeptide transport ATP-binding protein DppD; EC 7.4.2.9 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
40% identity, 92% coverage: 17:315/326 of query aligns to 21:317/326 of Q8RDH4
4fwiB Crystal structure of the nucleotide-binding domain of a dipeptide abc transporter (see paper)
40% identity, 92% coverage: 17:315/326 of query aligns to 20:306/310 of 4fwiB
Sites not aligning to the query:
P0AAH4 Putrescine export system ATP-binding protein SapD from Escherichia coli (strain K12) (see paper)
37% identity, 98% coverage: 1:318/326 of query aligns to 1:325/330 of P0AAH4
7z15I E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
40% identity, 73% coverage: 22:259/326 of query aligns to 21:251/253 of 7z15I
Sites not aligning to the query:
7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp (see paper)
40% identity, 71% coverage: 22:254/326 of query aligns to 21:246/250 of 7z18I
Sites not aligning to the query:
7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation (see paper)
40% identity, 71% coverage: 22:254/326 of query aligns to 21:246/250 of 7z16I
Sites not aligning to the query:
P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 3 papers)
35% identity, 77% coverage: 1:252/326 of query aligns to 2:241/343 of P30750
Sites not aligning to the query:
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form (see paper)
35% identity, 77% coverage: 1:252/326 of query aligns to 3:242/344 of 3tuzC
Sites not aligning to the query:
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form (see paper)
35% identity, 77% coverage: 1:252/326 of query aligns to 3:242/344 of 3tuiC
6cvlD Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
35% identity, 77% coverage: 1:252/326 of query aligns to 3:242/344 of 6cvlD
4u00A Crystal structure of ttha1159 in complex with adp (see paper)
35% identity, 72% coverage: 19:252/326 of query aligns to 17:236/241 of 4u00A
Sites not aligning to the query:
3c4jA Abc protein artp in complex with atp-gamma-s
31% identity, 77% coverage: 1:252/326 of query aligns to 1:238/242 of 3c4jA
3c41J Abc protein artp in complex with amp-pnp/mg2+
31% identity, 77% coverage: 1:252/326 of query aligns to 1:238/242 of 3c41J
2olkA Abc protein artp in complex with adp-beta-s
31% identity, 77% coverage: 1:252/326 of query aligns to 1:238/242 of 2olkA
2oljA Abc protein artp in complex with adp/mg2+
31% identity, 77% coverage: 1:252/326 of query aligns to 1:238/242 of 2oljA
7ahhC Opua inhibited inward-facing, sbd docked (see paper)
31% identity, 72% coverage: 20:253/326 of query aligns to 42:264/382 of 7ahhC
Sites not aligning to the query:
7aheC Opua inhibited inward facing (see paper)
31% identity, 72% coverage: 20:253/326 of query aligns to 42:264/382 of 7aheC
Sites not aligning to the query:
7ahdC Opua (e190q) occluded (see paper)
31% identity, 71% coverage: 20:249/326 of query aligns to 42:260/260 of 7ahdC
Sites not aligning to the query:
1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
33% identity, 73% coverage: 14:252/326 of query aligns to 16:241/353 of 1oxvD
Sites not aligning to the query:
1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
33% identity, 73% coverage: 14:252/326 of query aligns to 16:241/353 of 1oxvA
Sites not aligning to the query:
>BWI76_RS19190 FitnessBrowser__Koxy:BWI76_RS19190
MSLLKVNRLAVTGGEDIALVDNVSFTLEAGEMLGLVGESGSGKTVTCRALMRLLPGDGLR
ISGGEVVLDGRDILPLSEGQMSAVRGREIGMIFQNPTSHLNPVMTIGEQIAESRRLHFAA
NRRQAREDALALLRQVGIPDPQNRLNSYPHEFSGGMRQRAMIAVALASEPRLLIADEPTT
ALDVTVQMQILRLLSDLRAELGLAVIMITHDLGVVAQTCDRIAVMYGGRLCEVGDKREVL
AGPLHPYTRGLIDCQPASEGGRGRLTIIDGQPPSADHFPSGCRFHPRCRRADEACLQPPP
LHYGQDRHSHAVACHHRLPTLTRQEG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory