Comparing BWI76_RS22395 FitnessBrowser__Koxy:BWI76_RS22395 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 3 hits to proteins with known functional sites (download)
3qnqD Crystal structure of the transporter chbc, the iic component from the n,n'-diacetylchitobiose-specific phosphotransferase system (see paper)
30% identity, 96% coverage: 13:417/423 of query aligns to 3:423/436 of 3qnqD
P11162 PTS system lactose-specific EIICB component; EIICB-Lac; EII-Lac; EC 2.7.1.207 from Staphylococcus aureus (see paper)
29% identity, 97% coverage: 15:423/423 of query aligns to 10:423/570 of P11162
Sites not aligning to the query:
P24400 PTS system lactose-specific EIICB component; EIICB-Lac; EII-Lac; EC 2.7.1.207 from Lacticaseibacillus casei (Lactobacillus casei) (see paper)
28% identity, 97% coverage: 15:423/423 of query aligns to 6:418/577 of P24400
Sites not aligning to the query:
>BWI76_RS22395 FitnessBrowser__Koxy:BWI76_RS22395
MNIQLMNVAVDIIEQRLAPLANVLTRNNHITAMRDSFALAMPFVIVGSLLVPILFPPVSI
DGASFFGQFYFQLRPILLPTFELTIGLVALIVAFGASASLAKQYRLPERLCGLTGCLAFL
LFIGFRGNGAANLYLGGMGIFTALISSTYSIEIVRFFYKKGWCIRLPEEVPVMTRNGFQL
LIPLLVVMLSISVINALLLQSTGRILPELISEAVRPLVVASDTLTAVLISLFICNLLWFV
GIHGALIITGIMNPFWMTYLFENQQALAAGSATLPHIYLQGFWDFYLLIGGIGSTLPLVF
MAMRSRSRQLKSVGKIGLLPSLFNINEPILFGFPIIMNPVFLLPFLFVPLINACIAWYLT
QLGILDRAVAMLPWSMPAPLGAAWSANGSWKNLCMCLFAIFNAWMLYRPFFKVYERQLAD
AER
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory