Comparing BWI76_RS22405 FitnessBrowser__Koxy:BWI76_RS22405 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 3 hits to proteins with known functional sites (download)
3qnqD Crystal structure of the transporter chbc, the iic component from the n,n'-diacetylchitobiose-specific phosphotransferase system (see paper)
35% identity, 93% coverage: 12:420/440 of query aligns to 3:423/436 of 3qnqD
P11162 PTS system lactose-specific EIICB component; EIICB-Lac; EII-Lac; EC 2.7.1.207 from Staphylococcus aureus (see paper)
32% identity, 97% coverage: 7:434/440 of query aligns to 4:431/570 of P11162
Sites not aligning to the query:
P24400 PTS system lactose-specific EIICB component; EIICB-Lac; EII-Lac; EC 2.7.1.207 from Lacticaseibacillus casei (Lactobacillus casei) (see paper)
31% identity, 94% coverage: 14:428/440 of query aligns to 6:420/577 of P24400
Sites not aligning to the query:
>BWI76_RS22405 FitnessBrowser__Koxy:BWI76_RS22405
MSSLYAKLIAVIEQKITPMAGAIGQQKYVTSIRDGFITALPFMIVGSFLLVFIFPPFSPD
TTWGFARAWLQFSLDHRDALMLPFNFSMGVMTLFIAVGIAASLAKHHNLDSLTAGMLSLM
SFLLVAAPLKDGQISTAYFSGQGIFTAILVAIYSTELYAFLKRHNITIRLPPEVPAGVAR
SFEILIPVLAIVLTLHPLNLFIEAQLGMIIPEAIMSLVKPLVAASDTLPAILLSVLVCQV
LWFAGIHGALIVTGIMNPFWMANLSINQAAMAAGTAIPHIYVQGFWDHYLLIGGVGSTLP
LALMLLRSKAVHLRTIGRMGVVPGVFNINEPILFGAPIIMNPLFFLPFVLVPMINATLAY
FALKLDLVSRVVSMTPWTTPAPIGASWAANWSFSPVIMCLICMATAMVMYLPFLKAYEKQ
LLEQEHANAAAQAESAPQSA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory