Comparing BWI76_RS24125 FitnessBrowser__Koxy:BWI76_RS24125 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4ovrA Crystal structure of a trap periplasmic solute binding protein from xanthobacter autotrophicus py2, target efi-510329, with bound beta-d- galacturonate (see paper)
42% identity, 86% coverage: 45:326/328 of query aligns to 17:298/298 of 4ovrA
Sites not aligning to the query:
Q0B2F6 Solute-binding protein Bamb_6123 from Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD)) (see paper)
37% identity, 98% coverage: 6:325/328 of query aligns to 5:326/328 of Q0B2F6
4n17A Crystal structure of a trap periplasmic solute binding protein from burkholderia ambifaria (bam_6123), target efi-510059, with bound beta-d-galacturonate (see paper)
38% identity, 87% coverage: 40:325/328 of query aligns to 12:300/301 of 4n17A
Sites not aligning to the query:
4n15A Crystal structure of a trap periplasmic solute binding protein from burkholderia ambifaria (bam_6123), target efi-510059, with bound beta-d-glucuronate (see paper)
38% identity, 87% coverage: 40:325/328 of query aligns to 12:300/301 of 4n15A
Sites not aligning to the query:
4x8rA Crystal structure of a trap periplasmic solute binding protein from rhodobacter sphaeroides (rsph17029_2138, target efi-510205) with bound glucuronate
37% identity, 86% coverage: 28:310/328 of query aligns to 3:287/304 of 4x8rA
Q128M1 Solute-binding protein Bpro_3107 from Polaromonas sp. (strain JS666 / ATCC BAA-500) (see paper)
38% identity, 87% coverage: 35:320/328 of query aligns to 39:323/330 of Q128M1
4mhfA Crystal structure of a trap periplasmic solute binding protein from polaromonas sp. Js666 (bpro_3107), target efi-510173, with bound alpha/beta d-glucuronate, space group p21 (see paper)
38% identity, 87% coverage: 35:320/328 of query aligns to 9:293/301 of 4mhfA
4mijA Crystal structure of a trap periplasmic solute binding protein from polaromonas sp. Js666 (bpro_3107), target efi-510173, with bound alpha/beta d-galacturonate, space group p21 (see paper)
38% identity, 87% coverage: 35:320/328 of query aligns to 9:293/302 of 4mijA
4n8yA Crystal structure of a trap periplasmic solute binding protein from bradyrhizobium sp. Btai1 b (bbta_0128), target efi-510056 (bbta_0128), complex with alpha/beta-d-galacturonate (see paper)
38% identity, 87% coverage: 39:324/328 of query aligns to 4:298/300 of 4n8yA
4n91A Crystal structure of a trap periplasmic solute binding protein from anaerococcus prevotii dsm 20548 (apre_1383), target efi-510023, with bound alpha/beta d-glucuronate (see paper)
38% identity, 85% coverage: 28:306/328 of query aligns to 1:281/308 of 4n91A
4xfeA Crystal structure of a trap periplasmic solute binding protein from pseudomonas putida f1 (pput_1203), target efi-500184, with bound d- glucuronate
38% identity, 78% coverage: 46:302/328 of query aligns to 18:276/306 of 4xfeA
Sites not aligning to the query:
4x04A Crystal structure of a trap periplasmic solute binding protein from citrobacter koseri (cko_04899, target efi-510094) with bound d- glucuronate
34% identity, 80% coverage: 46:306/328 of query aligns to 19:282/301 of 4x04A
Sites not aligning to the query:
4pf8A Crystal structure of a trap periplasmic solute binding protein from sulfitobacter sp. Nas-14.1 (target efi-510299) with bound beta-d- galacturonate (see paper)
36% identity, 87% coverage: 43:326/328 of query aligns to 14:300/300 of 4pf8A
Sites not aligning to the query:
4ovqA Crystal structure of a trap periplasmic solute binding protein from roseobacter denitrificans, target efi-510230, with bound beta-d- glucuronate (see paper)
35% identity, 82% coverage: 58:325/328 of query aligns to 30:300/302 of 4ovqA
Sites not aligning to the query:
4p3lA Crystal structure of a trap periplasmic solute binding protein from chromohalobacter salexigens dsm 3043 (csal_2479), target efi-510085, with bound glucuronate, spg p6122 (see paper)
30% identity, 86% coverage: 45:326/328 of query aligns to 17:301/303 of 4p3lA
Sites not aligning to the query:
4pddA Crystal structure of a trap periplasmic solute binding protein from polaromonas sp js666 (bpro_0088, target efi-510167) bound to d- erythronate (see paper)
33% identity, 80% coverage: 53:313/328 of query aligns to 26:288/303 of 4pddA
Sites not aligning to the query:
P44542 Sialic acid-binding periplasmic protein SiaP; Extracytoplasmic solute receptor protein SiaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 2 papers)
31% identity, 94% coverage: 10:316/328 of query aligns to 7:315/329 of P44542
Q16BC9 Solute-binding protein RD1_1052 from Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans) (see paper)
29% identity, 90% coverage: 1:295/328 of query aligns to 1:295/325 of Q16BC9
2cexA Structure of a sialic acid binding protein (siap) in the presence of the sialic acid acid analogue neu5ac2en (see paper)
32% identity, 87% coverage: 31:316/328 of query aligns to 4:291/304 of 2cexA
Sites not aligning to the query:
2cexB Structure of a sialic acid binding protein (siap) in the presence of the sialic acid acid analogue neu5ac2en (see paper)
32% identity, 87% coverage: 31:316/328 of query aligns to 4:291/305 of 2cexB
Sites not aligning to the query:
>BWI76_RS24125 FitnessBrowser__Koxy:BWI76_RS24125
MKKLSFSRSLVCVSLLALLSSGASAAEKVTLKLAHNLERSHVVHQAFEEMSKEVNQLSNG
SMKIRIYPSSQMGSARETLELLQNGALDMTKGSASDLESFDNVYAIYNLPFLFKDQNHFN
KVVFGEVGKEIMESTKDKGFFALSVYVAGTRSFYAKKPITKPEDLKGLKIRVQASPTTLK
MVELMGGSPTPISFGEVYTAMQQGVVDGAENNVPSWVQTRHIEIAKVFSEDEHASIPDFL
VISSKTWDKLTPDQQQILIKAAKASEVYQQKLWDKIDADTRAQAKAMGGEIVKVDKAPFR
AAVQPLFDDFKKDPKQAALLAKFEAAAE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory