Comparing BWI76_RS24630 BWI76_RS24630 putrescine aminotransferase to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4uoxA Crystal structure of ygjg in complex with pyridoxal-5'-phosphate and putrescine (see paper)
94% identity, 97% coverage: 16:468/468 of query aligns to 1:453/453 of 4uoxA
P42588 Putrescine aminotransferase; PAT; PATase; Cadaverine transaminase; Diamine transaminase; Putrescine transaminase; Putrescine--2-oxoglutaric acid transaminase; Putrescine:2-OG aminotransferase; EC 2.6.1.82; EC 2.6.1.29 from Escherichia coli (strain K12) (see paper)
94% identity, 98% coverage: 10:468/468 of query aligns to 1:459/459 of P42588
4uoxC Crystal structure of ygjg in complex with pyridoxal-5'-phosphate and putrescine (see paper)
95% identity, 97% coverage: 12:467/468 of query aligns to 1:456/456 of 4uoxC
4ppmA Crystal structure of pige: a transaminase involved in the biosynthesis of 2-methyl-3-n-amyl-pyrrole (map) from serratia sp. Fs14 (see paper)
36% identity, 87% coverage: 45:453/468 of query aligns to 21:449/464 of 4ppmA
A0A0J9X1Q5 Aminotransferase PigE; EC 2.6.1.- from Serratia sp. (strain FS14) (see paper)
41% identity, 77% coverage: 45:404/468 of query aligns to 392:742/853 of A0A0J9X1Q5
Q5SHH5 [LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.118 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
43% identity, 80% coverage: 87:459/468 of query aligns to 41:395/395 of Q5SHH5
1wkhA Acetylornithine aminotransferase from thermus thermophilus hb8
43% identity, 80% coverage: 87:459/468 of query aligns to 33:387/387 of 1wkhA
Sites not aligning to the query:
1wkgA Acetylornithine aminotransferase from thermus thermophilus hb8
43% identity, 80% coverage: 87:459/468 of query aligns to 33:387/387 of 1wkgA
Sites not aligning to the query:
1vefA Acetylornithine aminotransferase from thermus thermophilus hb8
43% identity, 80% coverage: 87:459/468 of query aligns to 33:387/387 of 1vefA
Sites not aligning to the query:
Q9X2A5 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
38% identity, 83% coverage: 72:461/468 of query aligns to 16:385/385 of Q9X2A5
2ordA Crystal structure of acetylornithine aminotransferase (ec 2.6.1.11) (acoat) (tm1785) from thermotoga maritima at 1.40 a resolution
38% identity, 83% coverage: 72:461/468 of query aligns to 24:393/393 of 2ordA
A0QYS9 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
40% identity, 79% coverage: 85:453/468 of query aligns to 30:378/390 of A0QYS9
8ht4B Crystal structure of acetylornithine aminotransferase complex with plp from corynebacterium glutamicum
38% identity, 82% coverage: 72:453/468 of query aligns to 14:384/390 of 8ht4B
O66442 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Aquifex aeolicus (strain VF5)
38% identity, 79% coverage: 85:455/468 of query aligns to 23:373/376 of O66442
2eh6A Crystal structure of acetylornithine aminotransferase from aquifex aeolicus vf5
38% identity, 79% coverage: 85:455/468 of query aligns to 22:372/375 of 2eh6A
P9WPZ7 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
39% identity, 82% coverage: 71:453/468 of query aligns to 22:388/400 of P9WPZ7
Sites not aligning to the query:
6s54A Transaminase from pseudomonas fluorescens (see paper)
34% identity, 82% coverage: 78:460/468 of query aligns to 35:450/453 of 6s54A
Sites not aligning to the query:
7nncC Crystal structure of mycobacterium tuberculosis argd with prosthetic group pyridoxal-5'-phosphate and 6-methoxyquinoline-3-carboxylic acid
39% identity, 82% coverage: 71:453/468 of query aligns to 16:382/391 of 7nncC
7nn4A Crystal structure of mycobacterium tuberculosis argd with prosthetic group pyridoxal 5'-phosphate and 3-hydroxy-2-naphthoic acid.
39% identity, 82% coverage: 71:453/468 of query aligns to 16:382/391 of 7nn4A
Q6LFH8 Ornithine aminotransferase; PfOAT; Ornithine--oxo-acid aminotransferase; EC 2.6.1.13 from Plasmodium falciparum (isolate 3D7) (see paper)
33% identity, 78% coverage: 85:449/468 of query aligns to 40:398/414 of Q6LFH8
>BWI76_RS24630 BWI76_RS24630 putrescine aminotransferase
MIRPAQEHILNRLPSSASALACSAHALNLIEKRTLDHEEMKSLNQEVREYFKEHVNPGFL
AYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVENQL
AKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFSNSGTESVEAALKLAKAYQSPRGKF
TFVATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGDINAMRTLLSECKKTGDD
VAAVILEPIQGEGGVILPPPGYLPAVRKLCDEFGALLILDEVQTGMGRTGKMFACEHENV
QPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLL
TQNLPAQAEQKGDMLLDGFRQLAREYPDLVNEVRGKGMLMAIEFVDNEIGYDFASEMFRQ
RVLVAGTLNNARTIRVEPPLTLTLEQCEQVLKAARLALAALRVSVEEA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory