Comparing BWI76_RS26000 FitnessBrowser__Koxy:BWI76_RS26000 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P40732 Acetylornithine/succinyldiaminopimelate aminotransferase; ACOAT; DapATase; Succinyldiaminopimelate transferase; EC 2.6.1.11; EC 2.6.1.17 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
87% identity, 100% coverage: 1:405/406 of query aligns to 1:405/405 of P40732
4jevB N-acetylornithine aminotransferase from s. Typhimurium complexed with gabaculine
87% identity, 98% coverage: 7:405/406 of query aligns to 2:400/402 of 4jevB
4jewA N-acetylornithine aminotransferase from s. Typhimurium complexed with l-canaline
86% identity, 98% coverage: 7:405/406 of query aligns to 2:395/397 of 4jewA
2pb0A Structure of biosynthetic n-acetylornithine aminotransferase from salmonella typhimurium: studies on substrate specificity and inhibitor binding (see paper)
86% identity, 97% coverage: 12:405/406 of query aligns to 1:389/389 of 2pb0A
4addA Structural and functional study of succinyl-ornithine transaminase from e. Coli (see paper)
61% identity, 99% coverage: 5:405/406 of query aligns to 1:400/400 of 4addA
4adbB Structural and functional study of succinyl-ornithine transaminase from e. Coli (see paper)
61% identity, 99% coverage: 5:405/406 of query aligns to 1:400/401 of 4adbB
2ordA Crystal structure of acetylornithine aminotransferase (ec 2.6.1.11) (acoat) (tm1785) from thermotoga maritima at 1.40 a resolution
45% identity, 90% coverage: 23:389/406 of query aligns to 19:379/393 of 2ordA
Q9X2A5 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
45% identity, 90% coverage: 23:389/406 of query aligns to 11:371/385 of Q9X2A5
Q9M8M7 Acetylornithine aminotransferase, chloroplastic/mitochondrial; ACOAT; Acetylornithine transaminase; AOTA; Protein HOPW1-1-INTERACTING 1; EC 2.6.1.11 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
42% identity, 95% coverage: 15:398/406 of query aligns to 67:451/457 of Q9M8M7
Sites not aligning to the query:
O66442 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Aquifex aeolicus (strain VF5)
40% identity, 92% coverage: 23:394/406 of query aligns to 12:370/376 of O66442
2eh6A Crystal structure of acetylornithine aminotransferase from aquifex aeolicus vf5
40% identity, 92% coverage: 23:394/406 of query aligns to 11:369/375 of 2eh6A
Q5SHH5 [LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.118 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
40% identity, 95% coverage: 20:405/406 of query aligns to 23:395/395 of Q5SHH5
1wkhA Acetylornithine aminotransferase from thermus thermophilus hb8
40% identity, 95% coverage: 20:405/406 of query aligns to 15:387/387 of 1wkhA
Sites not aligning to the query:
1wkgA Acetylornithine aminotransferase from thermus thermophilus hb8
40% identity, 95% coverage: 20:405/406 of query aligns to 15:387/387 of 1wkgA
Sites not aligning to the query:
1vefA Acetylornithine aminotransferase from thermus thermophilus hb8
40% identity, 95% coverage: 20:405/406 of query aligns to 15:387/387 of 1vefA
Sites not aligning to the query:
3nx3A Crystal structure of acetylornithine aminotransferase (argd) from campylobacter jejuni
37% identity, 95% coverage: 17:401/406 of query aligns to 4:386/388 of 3nx3A
P9WPZ7 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
40% identity, 100% coverage: 2:406/406 of query aligns to 4:399/400 of P9WPZ7
Sites not aligning to the query:
7nncC Crystal structure of mycobacterium tuberculosis argd with prosthetic group pyridoxal-5'-phosphate and 6-methoxyquinoline-3-carboxylic acid
40% identity, 98% coverage: 7:404/406 of query aligns to 3:391/391 of 7nncC
7nn4A Crystal structure of mycobacterium tuberculosis argd with prosthetic group pyridoxal 5'-phosphate and 3-hydroxy-2-naphthoic acid.
40% identity, 98% coverage: 7:404/406 of query aligns to 3:391/391 of 7nn4A
A0QYS9 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
40% identity, 94% coverage: 10:389/406 of query aligns to 4:372/390 of A0QYS9
>BWI76_RS26000 FitnessBrowser__Koxy:BWI76_RS26000
MATEQPAITRATFDEVILPIYAPAEFIPVKGKGSRVWDQQGKEYVDFAGGIAVTALGHCH
PALVAALHEQGEKLWHTSNVFTNEPALRLGRKLVDATFADRVVFMNSGTEANETAFKLAR
HYTVTRHSPYKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPADIVHVPFNDLHAVK
AVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRDLCDQHQALLVFDEVQCGMGRTGSLFA
YMHYGVTPDILTSAKALGGGFPISAMLTTHDIASAFHAGSHGSTYGGNPLACAVGGAAFD
LINTPEVLDGVTAKRELFVQHLQQIDARFDLFSDIRGMGLLIGAELKPQYHGKARDFLYA
AAEAGVMVLNAGPDVMRFVPSLVIDDSDIAEGMARFAQAVERVLSA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory