Comparing BWI76_RS27535 FitnessBrowser__Koxy:BWI76_RS27535 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 4 hits to proteins with known functional sites (download)
P69786 PTS system glucose-specific EIICB component; EIICB-Glc; EII-Glc; EC 2.7.1.199 from Escherichia coli (strain K12) (see 5 papers)
32% identity, 98% coverage: 6:516/519 of query aligns to 3:474/477 of P69786
P09323 PTS system N-acetylglucosamine-specific EIICBA component; EIICBA-Nag; EII-Nag; EC 2.7.1.193 from Escherichia coli (strain K12) (see paper)
32% identity, 99% coverage: 7:518/519 of query aligns to 2:468/648 of P09323
Sites not aligning to the query:
6bvgA Crystal structure of bcmalt t280c-e54c crosslinked by divalent mercury (see paper)
29% identity, 79% coverage: 13:422/519 of query aligns to 6:445/447 of 6bvgA
1o2fB Complex of enzyme iiaglc and iibglc phosphocarrier protein hpr from escherichia coli nmr, restrained regularized mean structure (see paper)
40% identity, 13% coverage: 447:516/519 of query aligns to 6:75/77 of 1o2fB
>BWI76_RS27535 FitnessBrowser__Koxy:BWI76_RS27535
MSVIRQRILENMQKFSRAMIGAVLFLPVIGLILALSSVLTNPTLISETSFLHQLGQLLGD
TFWPLFGNLGLLFCVGISYGLAKDKKTEVALVSVMCFIMFLGANHSWLEHTHGLAEKING
EYYGTGQTQLLGFVVVDMGVFLGIILGCTIAWVHNKVSTIELPGALSMYGGAKLTLVAMT
PVVIFYAIAFTWFWPFMTHGIAALTGFMKNAGVAGVFVYGFFEKFLIPTGLHHFVWSPFQ
LTQIGGTLSVDGQVVSGTQAIFLAYMRHPDLTPVMNEALRFSQQGMTTIFGLAGASLAFY
HTAKPEKKMMAKAILLPAIITSMLTGITEPIEFTFLFVSPLLWVIHATLTAASQAICDIF
TVRPWGASGLIEFLIYNLPLPVSLTRWPGYVLIGIGQFAVYYVIFRTLVVKLNLKTPGRE
DDENVKLYSKADYRKKMGEPQSVTNEIINGLGGKENIISVDNCFTRLRVAIHNMDLVDDT
ILKSTGANGVVRNRNEVQVIYGVKVGQVRSRVDSWLAEN
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory