Comparing BWI76_RS27750 FitnessBrowser__Koxy:BWI76_RS27750 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 3 hits to proteins with known functional sites (download)
3qnqD Crystal structure of the transporter chbc, the iic component from the n,n'-diacetylchitobiose-specific phosphotransferase system (see paper)
32% identity, 93% coverage: 12:420/441 of query aligns to 3:423/436 of 3qnqD
P11162 PTS system lactose-specific EIICB component; EIICB-Lac; EII-Lac; EC 2.7.1.207 from Staphylococcus aureus (see paper)
32% identity, 99% coverage: 6:440/441 of query aligns to 3:437/570 of P11162
Sites not aligning to the query:
P24400 PTS system lactose-specific EIICB component; EIICB-Lac; EII-Lac; EC 2.7.1.207 from Lacticaseibacillus casei (Lactobacillus casei) (see paper)
32% identity, 97% coverage: 14:440/441 of query aligns to 6:438/577 of P24400
Sites not aligning to the query:
>BWI76_RS27750 FitnessBrowser__Koxy:BWI76_RS27750
MSSLYQSMIAVIEQSITPLAGRLGQQKYVIAIRDGFTAALPFMIIGSFMLVFIFPPFSPD
TTNGFARGWLDFSQQYREQLMLPFNLSMGVMTFFISVGIGASLGRQFQLDPVMSGLLAFM
AFLLVAAPYADGKISTQYLSGQGIFTALITAIYSTRVYAWLKQNNITIRLPKEVPTGVAR
SFEILIPVLVVIATLHPLNLFIEAQTGMILPQAIMHLLEPLVSASDSLPAILLSVLMCQI
FWFAGIHGSLIVTGIMNPFWMANLSANQAALAAGAALPHVYLQGFWDHYLLIGGVGSTLP
LAFLLLRSRVTHLRTIGKMGIVPSFFNINEPILFGAPIIMNPMMFIPFVFVPMINAVLAY
GATRLGWLSQVVSLTPWTTPAPIGASWAANWTLSPVVMCLICMVMSALIYLPFLRAYERS
LMKTEVEKAKAAVPVAETVSQ
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory