Comparing BWI76_RS27790 FitnessBrowser__Koxy:BWI76_RS27790 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 5 hits to proteins with known functional sites (download)
P0AGC0 Hexose-6-phosphate:phosphate antiporter from Escherichia coli (strain K12) (see paper)
32% identity, 100% coverage: 1:438/439 of query aligns to 1:450/463 of P0AGC0
P0AA76 D-galactonate transporter; D-galactonate/H(+) symporter from Escherichia coli (strain K12) (see paper)
22% identity, 65% coverage: 28:313/439 of query aligns to 13:303/430 of P0AA76
Sites not aligning to the query:
6e9nA E. Coli d-galactonate:proton symporter in the inward open form (see paper)
21% identity, 65% coverage: 28:313/439 of query aligns to 2:284/409 of 6e9nA
Sites not aligning to the query:
6e9oA E. Coli d-galactonate:proton symporter mutant e133q in the outward substrate-bound form (see paper)
26% identity, 33% coverage: 28:174/439 of query aligns to 5:153/393 of 6e9oA
Sites not aligning to the query:
Q5EXK5 3-hydroxybenzoate transporter MhbT from Klebsiella oxytoca (see paper)
23% identity, 92% coverage: 25:428/439 of query aligns to 19:428/452 of Q5EXK5
>BWI76_RS27790 FitnessBrowser__Koxy:BWI76_RS27790
MFAFLKSPPDAPPITDKQALDERYRYWRRHILLTIWLGYALFYFTRKSFNAAVPEILASN
VLTRSDIGLLATLFYITYGLSKFFSGIVSDRSNARYFMGIGLVATGVVNILFGFSTSLWA
FALLWALNAFFQGWGSPVCARLLTAWYSRTERGGWWALWNTAHNVGGALIPMVVGAAALH
YGWRTGMMIAGTLAILAGLFLCWRLRDRPQAVGLPAVGDWRHDELEIAQQQEGAGLTRKE
ILTKYVLLNPYIWLLSLCYVLVYVVRAAINDWGNLYMSETLGVDLVTANSAVTMFEVGGF
IGALVAGWGSDKLFNGNRGPMNLIFAAGILLSVGGLWLMPFASYVMQAACFFTAGFFVFG
PQMLIGMAAAECSHKEAAGAATGFVGLFAYLGASLSGWPLAQVMEIWHWSGFFVVIAIAA
GISALLLLPFLNAQAPREA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory