Comparing CA265_RS00205 FitnessBrowser__Pedo557:CA265_RS00205 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 15 hits to proteins with known functional sites (download)
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
22% identity, 95% coverage: 16:364/366 of query aligns to 3:378/380 of 5vo3A
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
22% identity, 95% coverage: 18:364/366 of query aligns to 1:374/377 of P44514
7rsfA Acetylornithine deacetylase from escherichia coli
27% identity, 88% coverage: 23:345/366 of query aligns to 6:358/380 of 7rsfA
7lgpB Dape enzyme from shigella flexneri
24% identity, 65% coverage: 23:261/366 of query aligns to 8:260/377 of 7lgpB
5xoyA Crystal structure of lysk from thermus thermophilus in complex with lysine (see paper)
24% identity, 94% coverage: 21:364/366 of query aligns to 2:337/341 of 5xoyA
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
22% identity, 94% coverage: 21:364/366 of query aligns to 4:374/376 of 4o23A
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
22% identity, 94% coverage: 21:364/366 of query aligns to 4:374/375 of 4pqaA
7uoiA Crystallographic structure of dape from enterococcus faecium
24% identity, 93% coverage: 20:361/366 of query aligns to 8:378/383 of 7uoiA
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
21% identity, 84% coverage: 58:364/366 of query aligns to 45:374/377 of 7t1qA
7m6uB Crystal structure of a circular permutation and computationally designed pro-enzyme of carboxypeptidase g2 (see paper)
28% identity, 51% coverage: 78:264/366 of query aligns to 17:202/392 of 7m6uB
Sites not aligning to the query:
1cg2A Carboxypeptidase g2 (see paper)
28% identity, 51% coverage: 78:264/366 of query aligns to 82:267/389 of 1cg2A
Sites not aligning to the query:
P06621 Carboxypeptidase G2; CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase; EC 3.4.17.11 from Pseudomonas sp. (strain RS-16) (see paper)
28% identity, 51% coverage: 78:264/366 of query aligns to 107:292/415 of P06621
Sites not aligning to the query:
4h2kA Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from haemophilus influenzae (see paper)
25% identity, 50% coverage: 16:197/366 of query aligns to 1:182/258 of 4h2kA
Sites not aligning to the query:
4mmoA The crystal structure of a m20 family metallo-carboxypeptidase sso-cp2 from sulfolobus solfataricus
31% identity, 35% coverage: 21:148/366 of query aligns to 3:138/437 of 4mmoA
Sites not aligning to the query:
Q8P8J5 N-acetyl-L-citrulline deacetylase; ACDase; Acetylcitrulline deacetylase; EC 3.5.1.- from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
20% identity, 95% coverage: 15:363/366 of query aligns to 1:364/366 of Q8P8J5
>CA265_RS00205 FitnessBrowser__Pedo557:CA265_RS00205
MNTISKIKLTEGPDLNHLYQESLELLSSLISIPSISGDEMLTADQIETFLNLQGINTFRK
HNNIWCYNKYMDASKPTILLNSHHDTVRPNEQYTRDPFSPIIEEEKIYGLGSNDAGGPLV
ALTATFLYFFERKDLSFNLCLAATAEEETSGELGIRSILPDLKEISFAIVGEPTGMHMAI
AEKGSMVIDCVSKGRSGHAAREEGDNAIYHALKDIDWFKSYLFPIMDDQPQPVKMTVTEI
RAGIQHNIVPAECSFTVDIRFDHNYNEREIVNTIINHTSCHFTVRPNVLKPSFIDMLHPV
VVSGLSLGRKTYLSPTSSDQGWLDMPSVKMGPGNSARSHTADEFIGIEEIEEGIDIYISL
LEGLKL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory