Comparing CA265_RS07225 FitnessBrowser__Pedo557:CA265_RS07225 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
4eayA Crystal structures of mannonate dehydratase from escherichia coli strain k12 complexed with d-mannonate (see paper)
54% identity, 98% coverage: 6:385/389 of query aligns to 3:389/395 of 4eayA
4eacC Crystal structure of mannonate dehydratase from escherichia coli strain k12 (see paper)
54% identity, 98% coverage: 6:385/389 of query aligns to 3:389/396 of 4eacC
3dbnA Crystal structure of the streptoccocus suis serotype2 d- mannonate dehydratase in complex with its substrate (see paper)
36% identity, 97% coverage: 6:381/389 of query aligns to 3:328/349 of 3dbnA
3bdkA Crystal structure of streptococcus suis mannonate dehydratase complexed with substrate analogue
36% identity, 97% coverage: 6:381/389 of query aligns to 3:328/349 of 3bdkA
>CA265_RS07225 FitnessBrowser__Pedo557:CA265_RS07225
MKYKKLEQTWRWYGPNDPVSLQDVKQAGATGIVTALHHIPHGEVWPLTDIQERKAIIEAA
GLTWSVVESVPVHEAIKTRRADAGKYIENYKTSLRNLSACGIKIVCYNFMPVLDWTRTQL
DLEMTDGSKALYFNWIDLAIFDLYILKREGAEADYSKSILDRAEAKYSTLTEQDLADLRV
NVLMGIPNEKEIELETLRNSINEYKAIGTQGLKENLKFFLSSIAEVCTTEGIKMTIHPDD
PPYAILGLPRIASTLEDFNYIIKEVDQAFNGVCFCTGSLGAGMGNNALEIFNAVKERVYF
AHLRNVKKDEDGSFYEADHLGGDVNMYEIMKALSEENALRDKSIPFRPDHGHQMLDDLAK
VTNPGYSAIGRLRGLAELRGLEIGVTGNY
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory