Comparing CA265_RS08140 FitnessBrowser__Pedo557:CA265_RS08140 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
1u08A Crystal structure and reactivity of ybdl from escherichia coli identify a methionine aminotransferase function. (see paper)
47% identity, 99% coverage: 5:381/381 of query aligns to 5:382/382 of 1u08A
2o0rA The three-dimensional structure of n-succinyldiaminopimelate aminotransferase from mycobacterium tuberculosis (see paper)
34% identity, 98% coverage: 6:379/381 of query aligns to 4:381/385 of 2o0rA
4wljA High resolution crystal structure of human kynurenine aminotransferase-i in complex with aminooxyacetate (see paper)
34% identity, 98% coverage: 7:379/381 of query aligns to 6:407/413 of 4wljA
1w7nA Crystal structure of human kynurenine aminotransferase i in pmp form (see paper)
34% identity, 98% coverage: 7:379/381 of query aligns to 6:410/415 of 1w7nA
1w7mA Crystal structure of human kynurenine aminotransferase i in complex with l-phe (see paper)
34% identity, 98% coverage: 7:379/381 of query aligns to 6:410/415 of 1w7mA
1w7lA Crystal structure of human kynurenine aminotransferase i (see paper)
34% identity, 98% coverage: 7:379/381 of query aligns to 6:410/415 of 1w7lA
Q16773 Kynurenine--oxoglutarate transaminase 1; Cysteine-S-conjugate beta-lyase; Glutamine transaminase K; GTK; Glutamine--phenylpyruvate transaminase; Kynurenine aminotransferase 1; Kynurenine aminotransferase I; KATI; Kynurenine--oxoglutarate transaminase I; EC 2.6.1.7; EC 4.4.1.13; EC 2.6.1.64 from Homo sapiens (Human) (see paper)
33% identity, 98% coverage: 7:379/381 of query aligns to 9:416/422 of Q16773
Q17CS8 Kynurenine aminotransferase; AeKAT; EC 2.6.1.-; EC 2.6.1.63; EC 2.6.1.7 from Aedes aegypti (Yellowfever mosquito) (Culex aegypti) (see 2 papers)
32% identity, 99% coverage: 2:379/381 of query aligns to 61:471/477 of Q17CS8
Sites not aligning to the query:
3fvuA Crystal structure of human kynurenine aminotransferase i in complex with indole-3-acetic acid (see paper)
33% identity, 98% coverage: 7:379/381 of query aligns to 6:413/419 of 3fvuA
3fvsB Human kynurenine aminotransferase i in complex with glycerol (see paper)
33% identity, 98% coverage: 7:379/381 of query aligns to 6:413/419 of 3fvsB
2r5eA Aedes kynurenine aminotransferase in complex with glutamine (see paper)
32% identity, 99% coverage: 2:379/381 of query aligns to 3:413/419 of 2r5eA
2r5cB Aedes kynurenine aminotransferase in complex with cysteine (see paper)
32% identity, 99% coverage: 2:379/381 of query aligns to 3:413/419 of 2r5cB
1yiyA Aedes aegypti kynurenine aminotransferase (see paper)
32% identity, 99% coverage: 2:379/381 of query aligns to 2:412/418 of 1yiyA
1v2fA Crystal structure of t.Th hb8 glutamine aminotransferase complex with 3-phenylpropionate (see paper)
32% identity, 100% coverage: 2:381/381 of query aligns to 1:367/368 of 1v2fA
1v2eA Crystal structure of t.Th hb8 glutamine aminotransferase complex with a-keto-g-methylthiobutyrate (see paper)
32% identity, 100% coverage: 2:381/381 of query aligns to 1:367/368 of 1v2eA
5verA Mouse kynurenine aminotransferase iii, re-refinement of the PDB structure 3e2z (see paper)
31% identity, 97% coverage: 7:376/381 of query aligns to 4:404/410 of 5verA
Sites not aligning to the query:
5vepA Mouse kynurenine aminotransferase iii, re-refinement of the PDB structure 3e2f (see paper)
31% identity, 97% coverage: 7:376/381 of query aligns to 4:404/410 of 5vepA
Sites not aligning to the query:
3e2zA Crystal structure of mouse kynurenine aminotransferase iii in complex with kynurenine (see paper)
31% identity, 97% coverage: 7:376/381 of query aligns to 4:404/410 of 3e2zA
3e2yA Crystal structure of mouse kynurenine aminotransferase iii in complex with glutamine (see paper)
31% identity, 97% coverage: 7:376/381 of query aligns to 4:404/410 of 3e2yA
1gdeA Crystal structure of pyrococcus protein a-1 e-form (see paper)
31% identity, 94% coverage: 23:381/381 of query aligns to 22:381/388 of 1gdeA
>CA265_RS08140 FitnessBrowser__Pedo557:CA265_RS08140
MLNIQSKLPGVSTTIFSVMSKLAAEHNAINLSQGFPDYACDPKLVELVNKAMQDGFNQYA
PMPGSTFLKETIAEKVENLYNIKYNPETEITVTAGGTQAIFTALASIINAGDEVIIFEPA
YDSYAPTIKLLGGLVKTYELAPPNYAIDWDMVKKLFTAKTRMIILNTPQNPTGSILSSDD
MKSLIKLISGTDILILSDEVYEHLIYDEQKHQSVMLYPELKQRSFIIASFGKLLHATGWK
LGYCLAPEKLTKEFRKVHQFNVFSVNSPMQQAIAHYIKEPKNYTEIGSFFQQKRDYFRSL
LAESRFKLLPCNGSYFQCVSYSSISDEKDTDFSMRLIKEFGVATIPVSAFYQKGIDHKII
RFCFAKENATLALAAEKLKNV
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory