SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing CA265_RS18550 FitnessBrowser__Pedo557:CA265_RS18550 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 17 hits to proteins with known functional sites (download)

5vdbA Crystal structure of a gnat superfamily acetyltransferase pa4794 in complex with bisubstrate analog 3 (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 52:140/159 of 5vdbA

query
sites
5vdbA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E
x
Y

T
x
Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N

L

S
x
G

G

N

L
x
M

V
x
M

V
|
V

S

A

P

P

K

A

Y

A

R
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R

K
x
G

A

L

G
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G

L

V

A
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A

K
x
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A

Y

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N

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M

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E

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N

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L

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A

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R

K

E

L

Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T
x
S

-

C

-

F

-

N

T

A

G
x
N

L

A

A
|
A

V

G

M

L

K
x
L

I
x
L

N
x
Y

S

T

D

Q

L

L

G

G

Y

Y

E

Q

P

P

V

R

T

A

Y

I

S

A

E

E

binding (3R,5S,9R,26S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14,20-trioxo-26-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15,21-triaza-3,5-diphosphaheptacosan-27-oic acid 3,5-dioxide (non-preferred name): Y68 (≠ E71), Q69 (≠ T72), G79 (≠ S82), M81 (≠ L84), M82 (≠ V85), V83 (= V86), R88 (= R91), G89 (≠ K92), G91 (= G94), A93 (= A96), R94 (≠ K97), S116 (≠ T120), N121 (≠ G122), A123 (= A124), L126 (≠ K127), L127 (≠ I128), Y128 (≠ N129)

Sites not aligning to the query:

binding (3R,5S,9R,26S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14,20-trioxo-26-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15,21-triaza-3,5-diphosphaheptacosan-27-oic acid 3,5-dioxide (non-preferred name): 28, 31, 141, 151

4l8aA Crystal structure of a gnat superfamily acetyltransferase pa4794 in ternary complex with n-phenylacetyl-gly-aclys and coa (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 52:140/159 of 4l8aA

query
sites
4l8aA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E
x
Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N
x
L

S
x
G

G
x
N

L
x
M

V
x
M

V
|
V

S

A

P

P

K

A

Y

A

R
|
R

K
x
G

A

L

G
|
G

L
x
V

A
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A

K
x
R

A

Y

I

L

K

I

N

G

E

V

I

M

F

E

G

N

L

L

S

A

R

R

K

E

L

Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T
x
S

-

C

-

F

-

N

T

A

G
x
N

L

A

A
|
A

V

G

M

L

K
x
L

I
x
L

N
x
Y

S

T

D

Q

L

L

G

G

Y

Y

E

Q

P

P

V

R

T

A

Y

I

S

A

E

E

binding N-(phenylacetyl)glycyl-N~6~-acetyl-L-lysine: Y68 (≠ E71), L78 (≠ N81), G79 (≠ S82), N80 (≠ G83), M81 (≠ L84), S116 (≠ T120)
binding coenzyme a: M81 (≠ L84), M82 (≠ V85), V83 (= V86), R88 (= R91), G89 (≠ K92), G91 (= G94), V92 (≠ L95), A93 (= A96), R94 (≠ K97), N121 (≠ G122), A123 (= A124), L126 (≠ K127), L127 (≠ I128), Y128 (≠ N129)

Sites not aligning to the query:

4koyA Crystal structure of a gnat superfamily acetyltransferase pa4794 in complex with cephalosporin c (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 52:140/159 of 4koyA

query
sites
4koyA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E
x
Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N

L

S
x
G

G
x
N

L
x
M

V

M

V

V

S

A

P

P

K

A

Y

A

R

R

K

G

A

L

G

G

L

V

A

A

K

R

A

Y

I

L

K

I

N

G

E

V

I

M

F

E

G

N

L

L

S

A

R

R

K

E

L

Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T

S

-

C

-

F

-

N

T

A

G

N

L

A

A

A

V

G

M

L

K

L

I

L

N

Y

S

T

D

Q

L

L

G

G

Y

Y

E

Q

P

P

V

R

T

A

Y

I

S

A

E

E

binding 4-(3-acetoxymethyl-2-carboxy-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-7-ylcarbamoyl)-1-carboxy-butyl-ammonium: Y68 (≠ E71), G79 (≠ S82), N80 (≠ G83), M81 (≠ L84)

Sites not aligning to the query:

binding 4-(3-acetoxymethyl-2-carboxy-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-7-ylcarbamoyl)-1-carboxy-butyl-ammonium: 29, 31, 49, 141, 151

4koxA Crystal structure of a gnat superfamily acetyltransferase pa4794 in complex with cefalotin (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 52:140/159 of 4koxA

query
sites
4koxA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E
x
Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N

L

S
x
G

G
x
N

L
x
M

V

M

V

V

S

A

P

P

K

A

Y

A

R

R

K

G

A

L

G

G

L

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A

A

K

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A

Y

I

L

K

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N

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N

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L

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Y

P

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K

K

A

A

K

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M

G

K

L

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T
x
S

-

C

-

F

-

N

T

A

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N

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A

A

A

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M

L

K

L

I

L

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A

E

E

binding cephalothin: Y68 (≠ E71), G79 (≠ S82), N80 (≠ G83), M81 (≠ L84), S116 (≠ T120)

Sites not aligning to the query:

binding cephalothin: 29, 31, 49, 141

4kowA Crystal structure of a gnat superfamily acetyltransferase pa4794 in complex with cefoxitin (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 52:140/159 of 4kowA

query
sites
4kowA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E
x
Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N

L

S
x
G

G
x
N

L

M

V

M

V

V

S

A

P

P

K

A

Y

A

R

R

K

G

A

L

G

G

L

V

A

A

K

R

A

Y

I

L

K

I

N

G

E

V

I

M

F

E

G

N

L

L

S

A

R

R

K

E

L

Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T
x
S

-

C

-
x
F

-

N

T

A

G

N

L

A

A

A

V

G

M

L

K

L

I

L

N

Y

S

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D

Q

L

L

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G

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Y

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P

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T

A

Y

I

S

A

E

E

binding cefoxitin: Y68 (≠ E71), G79 (≠ S82), N80 (≠ G83), S116 (≠ T120), F118 (vs. gap)

Sites not aligning to the query:

binding cefoxitin: 29, 31, 49, 141, 151

4kovA Crystal structure of a gnat superfamily acetyltransferase pa4794 in complex with cefuroxime (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 52:140/159 of 4kovA

query
sites
4kovA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E
x
Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N

L

S
x
G

G
x
N

L
x
M

V

M

V

V

S

A

P

P

K

A

Y

A

R

R

K

G

A

L

G

G

L

V

A

A

K

R

A

Y

I

L

K

I

N

G

E

V

I

M

F

E

G

N

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L

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A

R

R

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Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T
x
S

-

C

-
x
F

-

N

T

A

G

N

L

A

A

A

V

G

M

L

K

L

I

L

N

Y

S

T

D

Q

L

L

G

G

Y

Y

E

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P

P

V

R

T

A

Y

I

S

A

E

E

binding (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid: Y68 (≠ E71), G79 (≠ S82), N80 (≠ G83), M81 (≠ L84), S116 (≠ T120), F118 (vs. gap)

Sites not aligning to the query:

binding (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid: 29, 31, 49, 141, 151

4kouA Crystal structure of a gnat superfamily acetyltransferase pa4794 in complex with cefixime (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 52:140/159 of 4kouA

query
sites
4kouA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E
x
Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N

L

S
x
G

G

N

L

M

V

M

V

V

S

A

P

P

K

A

Y

A

R

R

K

G

A

L

G

G

L

V

A

A

K

R

A

Y

I

L

K

I

N

G

E

V

I

M

F

E

G

N

L

L

S

A

R

R

K

E

L

Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T

S

-

C

-
x
F

-

N

T

A

G

N

L

A

A

A

V

G

M

L

K

L

I

L

N

Y

S

T

D

Q

L

L

G

G

Y

Y

E

Q

P

P

V

R

T

A

Y

I

S

A

E

E

binding (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid: Y68 (≠ E71), G79 (≠ S82), F118 (vs. gap)

Sites not aligning to the query:

binding (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid: 14, 15, 27, 31, 49, 141, 142

4kotA Crystal structure of a gnat superfamily acetyltransferase pa4794 in complex with cefotaxime (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 52:140/159 of 4kotA

query
sites
4kotA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E
x
Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N

L

S
x
G

G
x
N

L
x
M

V

M

V

V

S

A

P

P

K

A

Y

A

R

R

K

G

A

L

G

G

L

V

A

A

K

R

A

Y

I

L

K

I

N

G

E

V

I

M

F

E

G

N

L

L

S

A

R

R

K

E

L

Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T

S

-

C

-
x
F

-

N

T

A

G

N

L

A

A

A

V

G

M

L

K

L

I

L

N

Y

S

T

D

Q

L

L

G

G

Y

Y

E

Q

P

P

V

R

T

A

Y

I

S

A

E

E

binding (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid: Y68 (≠ E71), G79 (≠ S82), N80 (≠ G83), M81 (≠ L84), F118 (vs. gap)

Sites not aligning to the query:

binding (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid: 29, 31, 49, 141, 151

4kosA Crystal structure of a gnat superfamily acetyltransferase pa4794 in complex with cefmetazole (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 52:140/159 of 4kosA

query
sites
4kosA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E
x
Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N
x
L

S
x
G

G
x
N

L
x
M

V

M

V

V

S

A

P

P

K

A

Y

A

R

R

K

G

A

L

G

G

L

V

A

A

K

R

A

Y

I

L

K

I

N

G

E

V

I

M

F

E

G

N

L

L

S

A

R

R

K

E

L

Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T
x
S

-

C

-
x
F

-

N

T

A

G

N

L

A

A

A

V

G

M

L

K

L

I

L

N

Y

S

T

D

Q

L

L

G

G

Y

Y

E

Q

P

P

V

R

T

A

Y

I

S

A

E

E

binding (6R,7S)-7-({[(cyanomethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid: Y68 (≠ E71), L78 (≠ N81), G79 (≠ S82), N80 (≠ G83), M81 (≠ L84), S116 (≠ T120), F118 (vs. gap)

Sites not aligning to the query:

binding (6R,7S)-7-({[(cyanomethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid: 29, 31, 32, 49, 141, 151

4korA Crystal structure of a gnat superfamily acetyltransferase pa4794 in complex with 7-aminocephalosporanic acid (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 52:140/159 of 4korA

query
sites
4korA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E
x
Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N

L

S
x
G

G
x
N

L
x
M

V

M

V

V

S

A

P

P

K

A

Y

A

R

R

K

G

A

L

G

G

L

V

A

A

K

R

A

Y

I

L

K

I

N

G

E

V

I

M

F

E

G

N

L

L

S

A

R

R

K

E

L

Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T

S

-

C

-

F

-

N

T

A

G

N

L

A

A

A

V

G

M

L

K

L

I

L

N

Y

S

T

D

Q

L

L

G

G

Y

Y

E

Q

P

P

V

R

T

A

Y

I

S

A

E

E

binding 7-aminocephalosporanic acid: Y68 (≠ E71), G79 (≠ S82), N80 (≠ G83), M81 (≠ L84)

Sites not aligning to the query:

binding 7-aminocephalosporanic acid: 29, 31, 49, 151

4klwA Crystal structure of a gnat superfamily acetyltransferase pa4794 in complex with 2-(aminocarbonyl)benzoate (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 52:140/159 of 4klwA

query
sites
4klwA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E
x
Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N

L

S
x
G

G

N

L

M

V

M

V

V

S

A

P

P

K

A

Y

A

R

R

K

G

A

L

G

G

L

V

A

A

K

R

A

Y

I

L

K

I

N

G

E

V

I

M

F

E

G

N

L

L

S

A

R

R

K

E

L

Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T
x
S

-

C

-

F

-

N

T

A

G

N

L

A

A

A

V

G

M

L

K

L

I

L

N

Y

S

T

D

Q

L

L

G

G

Y

Y

E

Q

P

P

V

R

T

A

Y

I

S

A

E

E

binding 2-carbamoylbenzoic acid: Y68 (≠ E71), G79 (≠ S82), S116 (≠ T120)

Sites not aligning to the query:

binding 2-carbamoylbenzoic acid: 29, 31, 49

4klvA Crystal structure of a gnat superfamily acetyltransferase pa4794 in complex with 4-methylumbelliferyl phosphate (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 52:140/159 of 4klvA

query
sites
4klvA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E
x
Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N

L

S
x
G

G
x
N

L

M

V

M

V

V

S

A

P

P

K

A

Y

A

R

R

K

G

A

L

G

G

L

V

A

A

K

R

A

Y

I

L

K

I

N

G

E

V

I

M

F

E

G

N

L

L

S

A

R

R

K

E

L

Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T

S

-

C

-

F

-

N

T

A

G

N

L

A

A

A

V

G

M

L

K

L

I

L

N

Y

S

T

D

Q

L

L

G

G

Y

Y

E

Q

P

P

V

R

T

A

Y

I

S

A

E

E

binding 4-methylumbelliferyl phosphate: Y68 (≠ E71), G79 (≠ S82), N80 (≠ G83)

Sites not aligning to the query:

binding 4-methylumbelliferyl phosphate: 29, 31, 49, 141

3pgpA Crystal structure of pa4794 - gnat superfamily protein in complex with accoa (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 52:140/159 of 3pgpA

query
sites
3pgpA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E

Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N

L

S

G

G

N

L
x
M

V

M

V
|
V

S

A

P

P

K

A

Y

A

R
|
R

K
x
G

A

L

G
|
G

L
x
V

A
|
A

K
x
R

A

Y

I

L

K

I

N

G

E

V

I

M

F

E

G

N

L

L

S

A

R

R

K

E

L

Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T

S

-

C

-

F

-

N

T

A

G
x
N

L

A

A
|
A

V

G

M

L

K
x
L

I
x
L

N
x
Y

S

T

D

Q

L

L

G

G

Y

Y

E

Q

P

P

V

R

T

A

Y

I

S

A

E

E

binding acetyl coenzyme *a: M81 (≠ L84), V83 (= V86), R88 (= R91), G89 (≠ K92), G91 (= G94), V92 (≠ L95), A93 (= A96), R94 (≠ K97), N121 (≠ G122), A123 (= A124), L126 (≠ K127), L127 (≠ I128), Y128 (≠ N129)

Sites not aligning to the query:

binding acetyl coenzyme *a: 28, 29

5vd6A Crystal structure of a gnat superfamily acetyltransferase pa4794 in complex with bisubstrate analog 6 (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 52:140/160 of 5vd6A

query
sites
5vd6A

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E
x
Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N

L

S
x
G

G
x
N

L
x
M

V

M

V
|
V

S

A

P

P

K

A

Y

A

R
|
R

K
x
G

A

L

G
|
G

L

V

A
|
A

K
x
R

A

Y

I

L

K

I

N

G

E

V

I

M

F

E

G

N

L

L

S

A

R

R

K

E

L

Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T
x
S

-

C

-

F

-

N

T

A

G
x
N

L

A

A

A

V

G

M

L

K

L

I
x
L

N
x
Y

S

T

D

Q

L

L

G

G

Y

Y

E

Q

P

P

V

R

T

A

Y

I

S

A

E

E

binding (3R,5S,9R,23S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14-dioxo-23-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatetracosan-24-oic acid 3,5-dioxide (non-preferred name): Y68 (≠ E71), G79 (≠ S82), N80 (≠ G83), M81 (≠ L84), V83 (= V86), R88 (= R91), G89 (≠ K92), G91 (= G94), A93 (= A96), R94 (≠ K97), S116 (≠ T120), N121 (≠ G122), L127 (≠ I128), Y128 (≠ N129)

Sites not aligning to the query:

binding (3R,5S,9R,23S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14-dioxo-23-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatetracosan-24-oic acid 3,5-dioxide (non-preferred name): 28, 31, 49, 141

4m3sA Crystal structure of a gnat superfamily acetyltransferase pa4794 in complex with hepes (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 52:140/160 of 4m3sA

query
sites
4m3sA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E
x
Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N

L

S
x
G

G

N

L

M

V

M

V

V

S

A

P

P

K

A

Y

A

R

R

K

G

A

L

G

G

L

V

A

A

K

R

A

Y

I

L

K

I

N

G

E

V

I

M

F

E

G

N

L

L

S

A

R

R

K

E

L

Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T
x
S

-

C

-

F

-

N

T

A

G

N

L

A

A

A

V

G

M

L

K

L

I

L

N

Y

S

T

D

Q

L

L

G

G

Y

Y

E

Q

P

P

V

R

T

A

Y

I

S

A

E

E

binding 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid: Y68 (≠ E71), G79 (≠ S82), S116 (≠ T120)

Sites not aligning to the query:

binding 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid: 28, 29, 141, 151

4oadA Crystal structure of a gnat superfamily acetyltransferase pa4794 in complex with chloramphenicol
31% identity, 38% coverage: 54:141/232 of query aligns to 53:141/160 of 4oadA

query
sites
4oadA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E

Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N

L

S

G

G

N

L
x
M

V

M

V
|
V

S

A

P

P

K

A

Y

A

R

R

K

G

A

L

G

G

L

V

A

A

K

R

A

Y

I

L

K

I

N

G

E

V

I

M

F

E

G

N

L

L

S

A

R

R

K

E

L

Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T

S

-

C

-

F

-

N

T

A

G
x
N

L

A

A

A

V
x
G

M

L

K

L

I

L

N

Y

S

T

D

Q

L

L

G

G

Y

Y

E

Q

P

P

V

R

T

A

Y

I

S

A

E

E

binding chloramphenicol: M82 (≠ L84), V84 (= V86), N122 (≠ G122), G125 (≠ V125)

Sites not aligning to the query:

binding chloramphenicol: 20, 21, 26, 29, 41, 45

4kubA Crystal structure of a gnat superfamily acetyltransferase pa4794 in complex with coa (see paper)
31% identity, 38% coverage: 54:141/232 of query aligns to 53:141/160 of 4kubA

query
sites
4kubA

S

S

V

T

I

V

A

A

F

V

H

H

K

-

D

D

G

G

S

Q

W

V

A

L

G

G

F

F

C

A

Y

N

I

F

E

Y

T

Q

W

W

S

Q

H

H

G

G

Q

D

F

F

V

C

A

A

N

L

S

G

G

N

L
x
M

V

M

V
|
V

S

A

P

P

K

A

Y

A

R
|
R

K
x
G

A

L

G
|
G

L
x
V

A
|
A

K
x
R

A

Y

I

L

K

I

N

G

E

V

I

M

F

E

G

N

L

L

S

A

R

R

K

E

L

Q

Y

Y

P

-

K

K

A

A

K

R

I

L

F

M

G

K

L

I

T

S

-

C

-

F

-

N

T

A

G
x
N

L

A

A
|
A

V

G

M

L

K
x
L

I
x
L

N

Y

S

T

D

Q

L

L

G

G

Y

Y

E

Q

P

P

V

R

T

A

Y

I

S

A

E

E

binding coenzyme a: M82 (≠ L84), V84 (= V86), R89 (= R91), G90 (≠ K92), G92 (= G94), V93 (≠ L95), A94 (= A96), R95 (≠ K97), N122 (≠ G122), A124 (= A124), L127 (≠ K127), L128 (≠ I128)

Query Sequence

>CA265_RS18550 FitnessBrowser__Pedo557:CA265_RS18550
MDINEFIVQVALPEHRVFAEEIVTEMAESAKARGTGIAKRSPEYISNKMQEGKSVIAFHK
DGSWAGFCYIETWSHGQFVANSGLVVSPKYRKAGLAKAIKNEIFGLSRKLYPKAKIFGLT
TGLAVMKINSDLGYEPVTYSELTQDEEFWKGCQSCVNFEILKMKERKNCMCTAMLYDPAE
KKHEVAKQFAEELQKKPKLYERFMRIKQRLVVKPKPKNGLKALLFLFTFLFK

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory