SitesBLAST

P00099 Cytochrome c-551; Cytochrome C8; Cytochrome c551 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 4 papers)
48% identity, 55% coverage: 46:116/128 of query aligns to 32:102/104 of P00099

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P00099

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H38 (= H52) binding axial binding residue
M83 (= M97) binding axial binding residue

Sites not aligning to the query:

1:22 signal peptide
23:104 modified: mature protein, Cytochrome c-551

351cA Structure of cytochrome c551 from p. Aeruginosa refined at 1.6 angstroms resolution and comparison of the two redox forms (see paper)
48% identity, 55% coverage: 46:116/128 of query aligns to 10:80/82 of 351cA

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binding protoporphyrin ix containing fe: C12 (= C48), C15 (= C51), H16 (= H52), G24 (= G60), P25 (= P61), Y27 (= Y63), L44 (= L80), R47 (≠ K83), I48 (= I84), Q53 (≠ K89), G54 (= G90), V55 (≠ N91), W56 (= W92), G57 (= G93), I59 (≠ L95), P60 (≠ S96), M61 (= M97)

6kq1A Crystal structure of cytochrome c551 from pseudomonas sp. Strain mt-1.
49% identity, 59% coverage: 43:117/128 of query aligns to 5:81/82 of 6kq1A

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binding heme c: C12 (= C48), C15 (= C51), H16 (= H52), G24 (= G60), P25 (= P61), V30 (≠ I66), Y34 (= Y70), L44 (= L80), H47 (≠ K83), I48 (= I84), Q53 (≠ K89), G54 (= G90), N55 (= N91), W56 (= W92), G57 (= G93), I59 (≠ L95), M61 (= M97), N64 (= N100)
binding zinc ion: K10 (vs. gap), E70 (= E106)

Sites not aligning to the query:

binding zinc ion: 2, 4

5xecC Heterodimer constructed from pa cyt c551-ht cyt c552 and ht cyt c552- pa cyt c551 chimeric proteins (see paper)
45% identity, 59% coverage: 41:116/128 of query aligns to 3:78/80 of 5xecC

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binding heme c: C10 (= C48), C13 (= C51), H14 (= H52), P23 (= P61), Y25 (= Y63), L42 (= L80), R45 (≠ K83), Q51 (≠ K89), V53 (≠ N91), W54 (= W92), G55 (= G93), I57 (≠ L95), M59 (= M97), N62 (= N100)

5aurA Hydrogenobacter thermophilus cytochrome c552 dimer formed by domain swapping at n-terminal region (see paper)
44% identity, 60% coverage: 41:117/128 of query aligns to 3:82/83 of 5aurA

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binding heme c: C10 (= C48), C13 (= C51), H14 (= H52), P26 (= P61), Y28 (= Y63), Y35 (= Y70), Y44 (≠ Q79), I49 (= I84), S54 (≠ K89), G55 (= G90), V56 (≠ N91), W57 (= W92), G58 (= G93), V60 (≠ L95), P61 (≠ S96), M62 (= M97), Q65 (≠ N100)

1corA Investigation of the solution conformation of cytochromE C-551 from pseudomonas stutzeri (see paper)
45% identity, 58% coverage: 43:116/128 of query aligns to 5:80/82 of 1corA

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binding heme c: K10 (vs. gap), C12 (= C48), C15 (= C51), H16 (= H52), V23 (≠ I59), G24 (= G60), P25 (= P61), L44 (= L80), H47 (≠ K83), I48 (= I84), S52 (≠ G88), Q53 (≠ K89), G54 (= G90), V55 (≠ N91), W56 (= W92), G57 (= G93), I59 (≠ L95), M61 (= M97), N64 (= N100)

1cchA The solution conformation of cytochromE C-551 from p.Stutzeri zobell determined by nmr+ (see paper)
47% identity, 59% coverage: 43:117/128 of query aligns to 5:81/82 of 1cchA

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binding heme c: C12 (= C48), C15 (= C51), H16 (= H52), L44 (= L80), H47 (≠ K83), I48 (= I84), S52 (≠ G88), Q53 (≠ K89), V55 (≠ N91), W56 (= W92), G57 (= G93), I59 (≠ L95), M61 (= M97), P62 (= P98), N64 (= N100)

2d0sA Crystal structure of the cytochrome c552 from moderate thermophilic bacterium, hydrogenophilus thermoluteolus (see paper)
44% identity, 59% coverage: 42:117/128 of query aligns to 4:78/79 of 2d0sA

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binding heme c: C10 (= C48), C13 (= C51), H14 (= H52), P23 (= P61), Y32 (= Y70), K43 (= K83), V44 (≠ I84), A49 (≠ K89), G50 (= G90), V51 (≠ N91), W52 (= W92), G53 (= G93), V55 (≠ L95), M57 (= M97), P58 (= P98), H60 (≠ N100)

1a56A Primary sequence and solution conformation of ferricytochromE C-552 from nitrosomonas europaea, nmr, mean structure refined with explicit hydrogen bond constraints (see paper)
43% identity, 61% coverage: 40:117/128 of query aligns to 2:80/81 of 1a56A

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binding heme c: N9 (≠ G47), C10 (= C48), C13 (= C51), H14 (= H52), V21 (≠ I59), G22 (= G60), P23 (= P61), K45 (= K83), I46 (= I84), S50 (≠ G88), W54 (= W92), Q56 (≠ E94), I57 (≠ L95), M59 (= M97), N62 (= N100), V63 (vs. gap), N64 (≠ P101)

4xxlA Crystal structure of class 1 cytochrome mtod from sideroxydans lithotrophicus es-1 (see paper)
33% identity, 59% coverage: 42:117/128 of query aligns to 10:90/92 of 4xxlA

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binding heme c: C16 (= C48), C19 (= C51), H20 (= H52), G28 (= G60), P29 (= P61), Y31 (= Y63), K37 (= K69), Y38 (= Y70), H51 (≠ K83), A58 (≠ G90), K59 (≠ N91), H68 (≠ S96)

Query Sequence

>Dsui_0927 FitnessBrowser__PS:Dsui_0927
MIYRLLMMGLVLSWGAVQAADNSASAARAFCDSGKLAKGAEIAVFRGCLGCHTVDSKRIG
PSYQEIAKKYPHTPDVVAQLAKKIRDGGKGNWGELSMPANPVSEAEAQTLAEWVLSLDEP
PARYSSNP

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory