Comparing Dsui_2039 FitnessBrowser__PS:Dsui_2039 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
7kb1C Complex of o-acety-l-homoserine aminocarboxypropyltransferase (mety) from thermotoga maritima and a key reaction intermediate (see paper)
58% identity, 99% coverage: 5:426/428 of query aligns to 4:426/428 of 7kb1C
7kb1A Complex of o-acety-l-homoserine aminocarboxypropyltransferase (mety) from thermotoga maritima and a key reaction intermediate (see paper)
58% identity, 99% coverage: 5:426/428 of query aligns to 4:426/428 of 7kb1A
2ctzA Crystal structure of o-acetyl homoserine sulfhydrylase from thermus thermophilus hb8
54% identity, 97% coverage: 8:424/428 of query aligns to 3:421/421 of 2ctzA
Q5SK88 O-acetyl-L-homoserine sulfhydrylase 1; OAH-sulfhydrylase 1; EC 2.5.1.- from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
54% identity, 97% coverage: 8:424/428 of query aligns to 3:421/421 of Q5SK88
8wkoA Crystal structure of o-acetylhomoserine sulfhydrylase from lactobacillus plantarum in the closed form
54% identity, 98% coverage: 5:425/428 of query aligns to 6:424/425 of 8wkoA
O13326 Homocysteine synthase; O-acetylhomoserine sulfhydrylase; OAH SHL; OAH sulfhydrylase; EC 2.5.1.49 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
55% identity, 98% coverage: 8:426/428 of query aligns to 8:429/429 of O13326
8erbK Crystal structure of fub7 in complex with vinylglycine ketimine (see paper)
52% identity, 98% coverage: 8:426/428 of query aligns to 6:427/429 of 8erbK
8erjB Crystal structure of fub7 in complex with e-2-aminocrotonate (see paper)
52% identity, 98% coverage: 8:426/428 of query aligns to 5:426/428 of 8erjB
8erjA Crystal structure of fub7 in complex with e-2-aminocrotonate (see paper)
52% identity, 98% coverage: 8:426/428 of query aligns to 5:426/428 of 8erjA
4omaA The crystal structure of methionine gamma-lyase from citrobacter freundii in complex with l-cycloserine pyridoxal-5'-phosphate (see paper)
46% identity, 99% coverage: 6:427/428 of query aligns to 6:396/396 of 4omaA
3jwbA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with norleucine (see paper)
46% identity, 99% coverage: 6:427/428 of query aligns to 6:396/396 of 3jwbA
3jwaA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with methionine phosphinate (see paper)
46% identity, 99% coverage: 6:427/428 of query aligns to 6:396/396 of 3jwaA
3jw9A Crystal structure of l-methionine gamma-lyase from citrobacter freundii with s-ethyl-cysteine (see paper)
46% identity, 99% coverage: 6:427/428 of query aligns to 6:396/396 of 3jw9A
5m3zA Crystal structure of citrobacter freundii methionine gamma-lyase with c115h replacement in the complex with l-norleucine (see paper)
46% identity, 99% coverage: 6:427/428 of query aligns to 5:395/395 of 5m3zA
4hf8A Crystal structure of l-methionine gamma-lyase from citrobacter freundii with glycine (see paper)
46% identity, 99% coverage: 6:427/428 of query aligns to 6:396/396 of 4hf8A
6egrA Crystal structure of citrobacter freundii methionine gamma-lyase with v358y replacement (see paper)
46% identity, 99% coverage: 6:427/428 of query aligns to 6:396/396 of 6egrA
3mkjA Methionine gamma-lyase from citrobacter freundii with pyridoximine-5'- phosphate (see paper)
45% identity, 99% coverage: 6:427/428 of query aligns to 6:385/386 of 3mkjA
8ovhA Crystal structure of o-acetyl-l-homoserine sulfhydrolase from saccharomyces cerevisiae in complex with pyridoxal-5'-phosphate (see paper)
48% identity, 97% coverage: 8:423/428 of query aligns to 5:391/400 of 8ovhA
5dx5A Crystal structure of methionine gamma-lyase from clostridium sporogenes (see paper)
40% identity, 98% coverage: 5:423/428 of query aligns to 5:394/399 of 5dx5A
3vk3A Crystal structure of l-methionine gamma-lyase from pseudomonas putida c116h mutant complexed with l-methionine (see paper)
41% identity, 97% coverage: 7:423/428 of query aligns to 8:393/397 of 3vk3A
>Dsui_2039 FitnessBrowser__PS:Dsui_2039
MADHQFGFDTLSLHAGQVPDAATGSRATPIYQTAAYVFDSPEHAASLFNLQTFGNVYSRL
SNPTVAVLEERIAALEGGKAAVAVASGMAAQMVALLNLCEAGDEIVAARTLYGGTHTQLD
VNFRKLGINTIFVDSDDPENFAKAITPRTKVIYAETMGNPGLNVLDIEAVARIANAAGLP
LFVDNTFASPYLCRPFEWGAAIVVHSATKFIGGHGTTLGGIIVESGKFPWDNGKFATMTE
PSPGYHGVKFYETFGNFGFTAKCRMEGLRTFGPALSPFNAFLLLQGVETLSLRMDRHCSN
ALAIARHLEAHPQVEWVNYPGLPSSKYHDLAQKYLPKGAGAVLTFGIKGGAAAGQEFIDS
VEFLSHLANIGDAKTLVIHPASTTHRQMTPEQQTAAGVPPDLIRLSVGLETLDDILWDID
QALAKATT
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory