Comparing Dsui_2042 FitnessBrowser__PS:Dsui_2042 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
7ba4A Structure of cystathionine gamma-lyase from pseudomonas aeruginosa
64% identity, 99% coverage: 5:391/392 of query aligns to 5:371/377 of 7ba4A
4iyoD Crystal structure of cystathionine gamma lyase from xanthomonas oryzae pv. Oryzae (xometc) in complex with e-site serine, a-site serine, a- site external aldimine structure with aminoacrylate and a-site iminopropionate intermediates (see paper)
63% identity, 98% coverage: 7:391/392 of query aligns to 4:380/384 of 4iyoD
4iyoB Crystal structure of cystathionine gamma lyase from xanthomonas oryzae pv. Oryzae (xometc) in complex with e-site serine, a-site serine, a- site external aldimine structure with aminoacrylate and a-site iminopropionate intermediates (see paper)
63% identity, 98% coverage: 7:391/392 of query aligns to 4:380/381 of 4iyoB
4iy7B Crystal structure of cystathionine gamma lyase (xometc) from xanthomonas oryzae pv. Oryzae in complex with e-site serine, a-site external aldimine structure with serine and a-site external aldimine structure with aminoacrylate intermediates (see paper)
63% identity, 98% coverage: 7:391/392 of query aligns to 4:380/381 of 4iy7B
4iy7A Crystal structure of cystathionine gamma lyase (xometc) from xanthomonas oryzae pv. Oryzae in complex with e-site serine, a-site external aldimine structure with serine and a-site external aldimine structure with aminoacrylate intermediates (see paper)
63% identity, 98% coverage: 7:391/392 of query aligns to 4:380/381 of 4iy7A
4ixzA Native structure of cystathionine gamma lyase (xometc) from xanthomonas oryzae pv. Oryzae at ph 9.0 (see paper)
63% identity, 98% coverage: 7:391/392 of query aligns to 4:380/381 of 4ixzA
6k1lB E53a mutant of a putative cystathionine gamma-lyase (see paper)
64% identity, 98% coverage: 7:392/392 of query aligns to 5:382/382 of 6k1lB
6k1lA E53a mutant of a putative cystathionine gamma-lyase (see paper)
64% identity, 98% coverage: 7:392/392 of query aligns to 5:382/382 of 6k1lA
4ixsB Native structure of xometc at ph 5.2 (see paper)
63% identity, 98% coverage: 7:391/392 of query aligns to 3:371/372 of 4ixsB
6cjaA Crystal structure of cystathionine beta-lyase from legionella pneumophila philadelphia 1 in complex with alanyl-plp and serine
62% identity, 99% coverage: 4:391/392 of query aligns to 1:380/381 of 6cjaA
4l0oH Structure determination of cystathionine gamma-synthase from helicobacter pylori
55% identity, 98% coverage: 9:391/392 of query aligns to 5:370/373 of 4l0oH
8j6nA Crystal structure of cystathionine gamma-lyase in complex with compound 1 (see paper)
54% identity, 99% coverage: 5:392/392 of query aligns to 7:386/390 of 8j6nA
7d7oB Crystal structure of cystathionine gamma-lyase from bacillus cereus atcc 14579 (see paper)
50% identity, 98% coverage: 9:391/392 of query aligns to 5:376/377 of 7d7oB
6nbaA Crystal structure of human cystathionine gamma lyase with s-3- carboxpropyl-l-cysteine (see paper)
53% identity, 100% coverage: 1:392/392 of query aligns to 3:386/389 of 6nbaA
P32929 Cystathionine gamma-lyase; CGL; CSE; Cysteine desulfhydrase; Cysteine-protein sulfhydrase; Gamma-cystathionase; Homocysteine desulfhydrase; EC 4.4.1.1; EC 4.4.1.2 from Homo sapiens (Human) (see 5 papers)
53% identity, 100% coverage: 1:392/392 of query aligns to 12:395/405 of P32929
Sites not aligning to the query:
3cogD Crystal structure of human cystathionase (cystathionine gamma lyase) in complex with dl-propargylglycine (see paper)
53% identity, 100% coverage: 1:392/392 of query aligns to 3:386/392 of 3cogD
3qhxA Crystal structure of cystathionine gamma-synthase metb (cgs) from mycobacterium ulcerans agy99 bound to hepes (see paper)
53% identity, 98% coverage: 6:391/392 of query aligns to 2:376/377 of 3qhxA
7mcyH Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound nl3 (see paper)
48% identity, 98% coverage: 9:391/392 of query aligns to 5:377/380 of 7mcyH
Sites not aligning to the query:
7mcuH Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound nl2 (see paper)
48% identity, 98% coverage: 9:391/392 of query aligns to 5:377/380 of 7mcuH
Sites not aligning to the query:
7mctH Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound nl1 (see paper)
48% identity, 98% coverage: 9:391/392 of query aligns to 5:377/380 of 7mctH
Sites not aligning to the query:
>Dsui_2042 FitnessBrowser__PS:Dsui_2042
MTHKQGFATRAIHAGQEPDPTTGAVSIPIYATSTYVQPALNEPKQYAGATFDYARSANPT
RLALERCIADLEGGAFATATGFAFASGLAASATVLELLPAGSHVVASDDLYGGSVRLFNR
VRSNSADLKVTYADFSSRESIEAAITPETKLLWVETPSNPLLKLVDLDLVAAIGKDRGLL
TVADNTFASPWIQRPLEHGFDIVVHSATKYLNGHSDVIAGVAVTARADLAERLAFLQNAA
GAVLGPFDAFLALRGLKTLALRMERHCANAEAIARWLEQHPAIEKVHYPGLASHPQHELA
KRQMRGFGGMVSAVVKGGLPAAKKLLENTKIFVLAESLGGVESLIELPALMTHASVPPEQ
RRRIGIDDGLVRLSVGVEDVEDLLADLEQALK
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory