Comparing Dsui_2904 FitnessBrowser__PS:Dsui_2904 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 8 hits to proteins with known functional sites (download)
4f4fA X-ray crystal structure of plp bound threonine synthase from brucella melitensis
42% identity, 99% coverage: 1:476/479 of query aligns to 2:459/464 of 4f4fA
1kl7A Crystal structure of threonine synthase from yeast (see paper)
43% identity, 92% coverage: 3:442/479 of query aligns to 7:461/509 of 1kl7A
Q42598 Threonine synthase; TS; EC 4.2.3.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
40% identity, 92% coverage: 1:441/479 of query aligns to 5:463/514 of Q42598
8g1yA Crystal structure of the threonine synthase from streptococcus pneumoniae in complex with pyridoxal 5-phosphate.
37% identity, 97% coverage: 1:463/479 of query aligns to 5:458/496 of 8g1yA
1vb3A Crystal structure of threonine synthase from escherichia coli
31% identity, 91% coverage: 17:451/479 of query aligns to 14:400/428 of 1vb3A
6nmxA Threonine synthase from bacillus subtilis atcc 6633 with plp and appa (see paper)
33% identity, 33% coverage: 119:275/479 of query aligns to 55:193/350 of 6nmxA
Sites not aligning to the query:
6cgqB Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala (see paper)
33% identity, 33% coverage: 119:275/479 of query aligns to 53:191/345 of 6cgqB
Sites not aligning to the query:
6cgqA Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala (see paper)
31% identity, 33% coverage: 119:275/479 of query aligns to 51:183/339 of 6cgqA
Sites not aligning to the query:
>Dsui_2904 FitnessBrowser__PS:Dsui_2904
MRYLSTRGDAASSPTQSFCDILLGGLAPDGGLYLPETYPQVSRAELDAWRQLSYAELAFA
VLSKFIDDIPPADLKAICDKTYTAQVYCHARPGDNAADVTPIHWLEQGKLALQELSNGPT
LAFKDMAMQLLGNLFEYVLAKRGEEINILGATSGDTGSAAEYAMRGKKGVRVFMLSPDGK
MSAFQRAQMYSLQDENIHNIAVRGMFDDAQDIVKAVSNDAAFKAKYKIGAVNSINWARVA
AQIVYYFKGYFGATENNDQQVAFCVPSGNFGNICAGHIARMMGLPIGKLILATNENNVLD
EFFKTGVYRPRKTAETFVTSSPSMDISKASNFERFVFDLVGRDPAKVRELWAQVDAGQAF
DLRGTPYMDKLAGFAFVSGASSHADRLATIRSCWETYGVMIDTHTADGLKVARENPIAGM
PTVVLETALPAKFAETIREALGREPEVPADLQGLEKLAQRVEVMDPDVNAVKAFIQARV
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory