Comparing Dsui_3052 FitnessBrowser__PS:Dsui_3052 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4mvaA 1.43 angstrom resolution crystal structure of triosephosphate isomerase (tpia) from escherichia coli in complex with acetyl phosphate. (see paper)
54% identity, 98% coverage: 5:239/241 of query aligns to 12:249/255 of 4mvaA
B1XB85 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Escherichia coli (strain K12 / DH10B) (see paper)
54% identity, 98% coverage: 5:239/241 of query aligns to 12:249/255 of B1XB85
8w06B Crystal structure of the reconstruction of the ancestral triosephosphate isomerase of the last opisthokont common ancestor obtained by maximum likelihood with pgh (see paper)
50% identity, 99% coverage: 1:238/241 of query aligns to 14:248/251 of 8w06B
Sites not aligning to the query:
6neeB Crystal structure of a reconstructed ancestor of triosephosphate isomerase from eukaryotes (see paper)
49% identity, 99% coverage: 1:238/241 of query aligns to 14:250/252 of 6neeB
Sites not aligning to the query:
P50921 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Moritella marina (Vibrio marinus) (see paper)
50% identity, 90% coverage: 10:227/241 of query aligns to 21:239/256 of P50921
Sites not aligning to the query:
1aw1A Triosephosphate isomerase of vibrio marinus complexed with 2- phosphoglycolate (see paper)
50% identity, 90% coverage: 10:227/241 of query aligns to 20:238/255 of 1aw1A
Sites not aligning to the query:
A0A1L5YRA2 Triosephosphate isomerase; TIM; Allergen Scy p 8; Methylglyoxal synthase; Triose-phosphate isomerase; Allergen Scy p 8.0101; EC 5.3.1.1; EC 4.2.3.3 from Scylla paramamosain (Mud crab) (see paper)
45% identity, 98% coverage: 5:240/241 of query aligns to 15:248/248 of A0A1L5YRA2
6oogA Crystal structure of triosephosphate isomerase from taenia solium in complex with 2pg (see paper)
49% identity, 86% coverage: 32:238/241 of query aligns to 44:250/252 of 6oogA
Sites not aligning to the query:
6ooiC Crystal structure of triosephosphate isomerase from schistosoma mansoni in complex with 2pg (see paper)
44% identity, 99% coverage: 1:238/241 of query aligns to 18:253/255 of 6ooiC
Sites not aligning to the query:
P36204 Bifunctional PGK/TIM; EC 2.7.2.3; EC 5.3.1.1 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
43% identity, 98% coverage: 1:237/241 of query aligns to 412:647/654 of P36204
Sites not aligning to the query:
4y96A Crystal structure of triosephosphate isomerase from gemmata obscuriglobus (see paper)
45% identity, 99% coverage: 1:239/241 of query aligns to 12:249/250 of 4y96A
Sites not aligning to the query:
P07669 Triosephosphate isomerase; TIM; Triose-phosphate isomerase; EC 5.3.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
45% identity, 95% coverage: 1:230/241 of query aligns to 13:239/249 of P07669
P00942 Triosephosphate isomerase; TIM; Triose-phosphate isomerase; EC 5.3.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
48% identity, 88% coverage: 26:238/241 of query aligns to 36:246/248 of P00942
Sites not aligning to the query:
5eywA Crystal structure of litopenaeus vannamei triosephosphate isomerase complexed with 2-phosphoglycolic acid (see paper)
46% identity, 97% coverage: 5:238/241 of query aligns to 11:243/244 of 5eywA
Sites not aligning to the query:
2y63A Crystal structure of leishmanial e65q-tim complexed with bromohydroxyacetone phosphate (see paper)
46% identity, 95% coverage: 2:230/241 of query aligns to 14:240/249 of 2y63A
Sites not aligning to the query:
2y61A Crystal structure of leishmanial e65q-tim complexed with s-glycidol phosphate (see paper)
46% identity, 95% coverage: 2:230/241 of query aligns to 14:240/249 of 2y61A
Sites not aligning to the query:
2vxnA E65q-tim complexed with phosphoglycolohydroxamate at 0.82 a resolution (see paper)
46% identity, 95% coverage: 2:230/241 of query aligns to 14:240/249 of 2vxnA
Sites not aligning to the query:
1if2A X-ray structure of leishmania mexicana triosephosphate isomerase complexed with ipp (see paper)
46% identity, 95% coverage: 2:230/241 of query aligns to 14:240/249 of 1if2A
Sites not aligning to the query:
1ci1B Crystal structure of triosephosphate isomerase from trypanosoma cruzi in hexane (see paper)
48% identity, 89% coverage: 26:239/241 of query aligns to 36:248/249 of 1ci1B
Sites not aligning to the query:
3ypiA Electrophilic catalysis in triosephosphase isomerase: the role of histidine-95 (see paper)
48% identity, 88% coverage: 26:238/241 of query aligns to 35:245/247 of 3ypiA
Sites not aligning to the query:
>Dsui_3052 FitnessBrowser__PS:Dsui_3052
MHGGLAANRSLLQGVVAGVKGLAAAVECAVCVPYPYLAQAQQELAKTEVSWGAQNLSEQV
SGAFTGEVSAAMLKDFGCRYVIVGHSERRALYGEDDGLVAKKFKQALAGGLVPILCVGET
LAQRESGQAAEVVAAQLDAVLDAAGVEVFAGAVVAYEPVWAIGTGLTASPAQAQAVHEGI
RARLAARNAEVAAGVRVLYGGSVKAGNAAELFAMPDIDGALVGGASLVAEEFVAICRAAA
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Lawrence Berkeley National Laboratory