Comparing Echvi_0093 FitnessBrowser__Cola:Echvi_0093 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
7poaA An irreversible, promiscuous and highly thermostable claisen- condensation biocatalyst drives the synthesis of substituted pyrroles
32% identity, 91% coverage: 32:369/373 of query aligns to 47:385/398 of 7poaA
8h29A Serine palmitoyltransferase from sphingobacterium multivorum complexed with l-threonine (see paper)
30% identity, 90% coverage: 34:368/373 of query aligns to 48:382/394 of 8h29A
8h21A Serine palmitoyltransferase from sphingobacterium multivorum complexed with l-alanine (see paper)
30% identity, 90% coverage: 34:368/373 of query aligns to 48:382/394 of 8h21A
8h20A Serine palmitoyltransferase from sphingobacterium multivorum complexed with glycine (see paper)
30% identity, 90% coverage: 34:368/373 of query aligns to 48:382/394 of 8h20A
8h1yA Serine palmitoyltransferase from sphingobacterium multivorum complexed with l-homoserine (see paper)
30% identity, 90% coverage: 34:368/373 of query aligns to 48:382/394 of 8h1yA
8h1qA Serine palmitoyltransferase from sphingobacterium multivorum complexed with l-serine (see paper)
30% identity, 90% coverage: 34:368/373 of query aligns to 48:382/394 of 8h1qA
8guhA Serine palmitoyltransferase from sphingobacterium multivorum complexed with tris (see paper)
30% identity, 90% coverage: 34:368/373 of query aligns to 48:382/394 of 8guhA
3a2bA Crystal structure of serine palmitoyltransferase from sphingobacterium multivorum with substrate l-serine (see paper)
30% identity, 90% coverage: 34:368/373 of query aligns to 48:382/392 of 3a2bA
Q5W264 4-hydroxy-2,2'-bipyrrole-5-methanol synthase PigH; HBM synthase; Aminotransferase PigH; EC 2.3.2.- from Serratia sp. (strain ATCC 39006) (see paper)
28% identity, 91% coverage: 34:373/373 of query aligns to 290:629/653 of Q5W264
Sites not aligning to the query:
Q0P5L8 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; AKB ligase; Aminoacetone synthase; Glycine acetyltransferase; EC 2.3.1.29 from Bos taurus (Bovine) (see paper)
30% identity, 91% coverage: 28:368/373 of query aligns to 64:405/419 of Q0P5L8
Sites not aligning to the query:
P0AB77 2-amino-3-ketobutyrate coenzyme A ligase; AKB ligase; Glycine acetyltransferase; EC 2.3.1.29 from Escherichia coli (strain K12) (see paper)
28% identity, 90% coverage: 32:368/373 of query aligns to 45:384/398 of P0AB77
1fc4A 2-amino-3-ketobutyrate coa ligase (see paper)
28% identity, 90% coverage: 32:368/373 of query aligns to 48:387/401 of 1fc4A
2g6wA Suicide inhibition of a-oxamine synthase: structures of the covalent adducts of 8-amino-7-oxonanoate synthase with trifluoroalanine (see paper)
29% identity, 91% coverage: 32:372/373 of query aligns to 41:380/383 of 2g6wA
P12998 8-amino-7-oxononanoate synthase; AONS; 7-keto-8-amino-pelargonic acid synthase; 7-KAP synthase; KAPA synthase; 8-amino-7-ketopelargonate synthase; EC 2.3.1.47 from Escherichia coli (strain K12) (see 2 papers)
29% identity, 91% coverage: 32:372/373 of query aligns to 42:381/384 of P12998
Sites not aligning to the query:
3tqxA Structure of the 2-amino-3-ketobutyrate coenzyme a ligase (kbl) from coxiella burnetii (see paper)
26% identity, 96% coverage: 11:368/373 of query aligns to 22:383/396 of 3tqxA
1djeA Crystal structure of the plp-bound form of 8-amino-7-oxonanoate synthase (see paper)
29% identity, 91% coverage: 32:372/373 of query aligns to 41:380/383 of 1djeA
1dj9A Crystal structure of 8-amino-7-oxonanoate synthase (or 7-keto- 8aminipelargonate or kapa synthase) complexed with plp and the product 8(s)-amino-7-oxonanonoate (or kapa). The enzyme of biotin biosynthetic pathway. (see paper)
29% identity, 91% coverage: 32:372/373 of query aligns to 41:380/383 of 1dj9A
Sites not aligning to the query:
7v58B Structural insights into the substrate selectivity of acyl-coa transferase (see paper)
27% identity, 91% coverage: 32:369/373 of query aligns to 47:387/400 of 7v58B
2x8uA Sphingomonas wittichii serine palmitoyltransferase (see paper)
30% identity, 65% coverage: 36:279/373 of query aligns to 51:294/399 of 2x8uA
7cqiT Cryo-em structure of the substrate-bound spt-ormdl3 complex (see paper)
30% identity, 69% coverage: 30:288/373 of query aligns to 125:393/498 of 7cqiT
Sites not aligning to the query:
>Echvi_0093 FitnessBrowser__Cola:Echvi_0093
MEKHRQFIRAKLEQVAASNRLRTLKNPPMGNIDFFSNDYLGYATKGFLKQATNPAYDAAW
TGATGSRLISGNHPEMEQLERDVAKFMDCPAALLYNSGYMANTGLLSALGDKDSIFLFDE
HVHASIKEGMRLGFGQKAAFKHHDLEDLERKLTHHDQKGKRLFVLTEGLFSMHGDIPDVG
KLLGICEKHGAALIIDEAHALGTLGKEKKGVSHEFSRHPNLLARIITFGKAAGGHGAMVL
GNEDLRSFLVNFSRAFIYTTAPSRDQVRSIDAAMKLMAAKVNFEAMDRAVATFLETVPSS
STGFSKNISPIQYWRCADVPLLKEKVNQLQQSGINCYPILSPTVKKGEERIRIVLHAFNT
PEEIKKLINILHA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory