Comparing Echvi_1869 FitnessBrowser__Cola:Echvi_1869 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
4eacC Crystal structure of mannonate dehydratase from escherichia coli strain k12 (see paper)
55% identity, 98% coverage: 5:385/387 of query aligns to 5:392/396 of 4eacC
4eayA Crystal structures of mannonate dehydratase from escherichia coli strain k12 complexed with d-mannonate (see paper)
55% identity, 98% coverage: 5:385/387 of query aligns to 5:392/395 of 4eayA
3dbnA Crystal structure of the streptoccocus suis serotype2 d-mannonate dehydratase in complex with its substrate (see paper)
37% identity, 98% coverage: 6:386/387 of query aligns to 6:337/349 of 3dbnA
3bdkA Crystal structure of streptococcus suis mannonate dehydratase complexed with substrate analogue
37% identity, 98% coverage: 6:386/387 of query aligns to 6:337/349 of 3bdkA
>Echvi_1869 FitnessBrowser__Cola:Echvi_1869
MNLIQTWRWYGPNDPVSLQDVRQAGATGVVSALHQIPHGDEWPIQLIQERKATIEAAGLE
WSVVESVPVHEAIKTRNDHAEYYLENYRKTLRNLSKCGIKTVCYNFMPVLDWTRTDLALP
LANGAKALYLDWTDLAVFDLKILGRAGGEAFYKPEILAKVEERYAAMTKEQQAALQEIVL
MGVPTEGGVTLEALQESIEVYSSIGKHGLQENLTYFLENIAEVCEEEGIRMTIHPDDPPF
PILGLPRIASSKEDLEFILQAVDRPFNGICFCTGSLGAGDHNDLPAMLDAVGDRVYFAHL
RNVKKDALGNFHESDHLDGDVDMCAIMERLVKLNAQRHQAIPFRPDHGHQMLDDLQKVTN
PGYSAIGRLKGLAELRGLEMGIKNSGI
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory