Comparing Echvi_2481 FitnessBrowser__Cola:Echvi_2481 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 9 hits to proteins with known functional sites (download)
5ti1H Crystal structure of fumarylacetoacetate hydrolase from burkholderia xenovorans lb400
52% identity, 97% coverage: 10:421/425 of query aligns to 14:428/430 of 5ti1H
P16930 Fumarylacetoacetase; FAA; Beta-diketonase; Fumarylacetoacetate hydrolase; EC 3.7.1.2 from Homo sapiens (Human) (see 14 papers)
53% identity, 97% coverage: 11:421/425 of query aligns to 2:415/419 of P16930
Sites not aligning to the query:
P35505 Fumarylacetoacetase; FAA; Beta-diketonase; Fumarylacetoacetate hydrolase; EC 3.7.1.2 from Mus musculus (Mouse) (see 3 papers)
52% identity, 97% coverage: 11:421/425 of query aligns to 2:415/419 of P35505
1hyoB Crystal structure of fumarylacetoacetate hydrolase complexed with 4- (hydroxymethylphosphinoyl)-3-oxo-butanoic acid (see paper)
52% identity, 97% coverage: 11:421/425 of query aligns to 4:417/419 of 1hyoB
2hzyA Mouse fumarylacetoacetate hydrolase complexes with a transition-state mimic of the complete substrate (see paper)
52% identity, 97% coverage: 11:421/425 of query aligns to 2:415/416 of 2hzyA
1qcoA Crystal structure of fumarylacetoacetate hydrolase complexed with fumarate and acetoacetate (see paper)
52% identity, 97% coverage: 11:421/425 of query aligns to 2:415/416 of 1qcoA
6iymA Fumarylacetoacetate hydrolase (eafah) from psychrophilic exiguobacterium antarcticum (see paper)
26% identity, 40% coverage: 188:359/425 of query aligns to 98:243/277 of 6iymA
8skyB Crystal structure of yisk from bacillus subtilis in complex with oxalate (see paper)
35% identity, 16% coverage: 200:265/425 of query aligns to 142:201/303 of 8skyB
Sites not aligning to the query:
8sutA Crystal structure of yisk from bacillus subtilis in complex with reaction product 4-hydroxy-2-oxoglutaric acid (see paper)
35% identity, 16% coverage: 200:265/425 of query aligns to 143:202/303 of 8sutA
Sites not aligning to the query:
>Echvi_2481 FitnessBrowser__Cola:Echvi_2481
MKEQKVKPLKSWVQIPKNSDFTIYNLPFGVFRNKRLSPRIGMAIGDKIVDLHVLFCEGFF
SSIHLPEEVFLKDSLNEFMALGKPMTRKVREMVQELLLEENTALKDHRARGKVMVNRKEA
KMLMPVKVGDYTDFYSSKEHATNVGTMFRDPENALMPNWKHLPVGYHGRASSIVPSGTPI
HRPKGQFKAPDAEKPSFGPSRRLDFELEMAFITSNPTKMGTSIRTQEAEEHIFGFVLFND
WSARDIQAWEYVPLGPFLGKSFASSISPWVVTLEALAPFRTKSPKPEEPLLPYLQCEQDH
GFDIHLEVGIQPEGKQETIVCRSNYKYLYWNIAQQLAHQTVNGCNINVGDMYASGTISGP
EESSFGSMLELAWKGTKPIRLDCGAERSFIEDGDTVTMRGYAEKDGVRVGFGEVSTAVMP
SNGKG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory