SitesBLAST

P07464 Galactoside O-acetyltransferase; GAT; Acetyl-CoA:galactoside 6-O-acetyltransferase; Thiogalactoside acetyltransferase; Thiogalactoside transacetylase; EC 2.3.1.18 from Escherichia coli (strain K12) (see 3 papers)
33% identity, 42% coverage: 108:189/195 of query aligns to 98:189/203 of P07464

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P07464

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H115 (vs. gap) mutation to A: Results in an 1800-fold decrease in catalytic activity.
S142 (≠ T142) binding in other chain
A160 (= A160) binding in other chain
TK 165:166 (≠ TH 165:166) binding
R180 (≠ K180) binding
R183 (≠ K183) binding in other chain

Sites not aligning to the query:

1 modified: Initiator methionine, Removed; Partial
17 binding
71 binding
85 binding in other chain; binding in other chain
93 binding

1krrA Galactoside acetyltransferase in complex with acetyl-coenzyme a (see paper)
33% identity, 42% coverage: 108:189/195 of query aligns to 97:188/200 of 1krrA

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1krrA

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binding acetyl coenzyme *a: I103 (≠ V114), A104 (≠ L115), P105 (= P116), T112 (vs. gap), H114 (vs. gap), G140 (= G141), S141 (≠ T142), N146 (≠ L147), G158 (≠ A159), A159 (= A160), A174 (≠ G175), P177 (= P178), R182 (≠ K183)

Sites not aligning to the query:

binding acetyl coenzyme *a: 84

8vr6A Crystal structure of the pcryo_0619 n-acetryltransferase from psychrobacter cryohalolentis k5 in the presence of coa-disulfide
29% identity, 56% coverage: 74:182/195 of query aligns to 60:168/177 of 8vr6A

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8vr6A

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binding [[(2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{R})-4-[[3-[2-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate: Y97 (≠ N111), H99 (≠ T113), D100 (≠ V114), T101 (≠ L115), V133 (≠ L147), L149 (≠ V163), L151 (≠ T165), S163 (≠ I177), P164 (= P178)

Query Sequence

>Echvi_2964 FitnessBrowser__Cola:Echvi_2964
MELIKTKEDLNRVLKIEKAKLNIKRPFLMWISYSEGYRVYRFFKNLRYLEFYLNKKKNPW
DYLPLAWRYWNHRRMKLKFSFYIHPNTLGEGFHLVHSGFVRIAVFANIGKNCTVLPRVLI
GKKKPRIEDPRVLIGEDCYIGTGVTILGPIKIGNNVTIAAGSVVTHDVPDNCVIGGIPAK
IIKYKNSPDPVSSSA

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SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory