Comparing Echvi_3100 FitnessBrowser__Cola:Echvi_3100 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
4eayA Crystal structures of mannonate dehydratase from escherichia coli strain k12 complexed with d-mannonate (see paper)
59% identity, 98% coverage: 2:377/382 of query aligns to 8:389/395 of 4eayA
4eacC Crystal structure of mannonate dehydratase from escherichia coli strain k12 (see paper)
59% identity, 98% coverage: 2:377/382 of query aligns to 8:389/396 of 4eacC
3dbnA Crystal structure of the streptoccocus suis serotype2 d- mannonate dehydratase in complex with its substrate (see paper)
39% identity, 98% coverage: 1:373/382 of query aligns to 7:328/349 of 3dbnA
3bdkA Crystal structure of streptococcus suis mannonate dehydratase complexed with substrate analogue
39% identity, 98% coverage: 1:373/382 of query aligns to 7:328/349 of 3bdkA
>Echvi_3100 FitnessBrowser__Cola:Echvi_3100
MRWYGPQDPVTLADIRQAGATGIVSALHHLPNGVIWSREEIKKRKDTIEAAGLTWSVVES
IPVHENIKTRSGNYQEYIANYKTSIGNLAAEGIHTVCYNFMPVLDWTRTDLAYELPNGAK
ALRFELQALAAFDLFILQRPNAEKDYSEQVIKRAEAYFKEMTEDAEQLLTNNIIAGLPGA
EEGYSLKAFQQVLDTYQHIDADKLATNLRLFLEEIIPTAEKNRVFMAIHPDDPPFPMFGL
PRVMSTIDDVKRLVTETPSEYNGITFCTGSFGVRADNDLPQIIREHGDHIHFIHLRSTQR
DAYGNFHEANHLEGDVPIVAVIKELIKVQSRRQKSLPMRPDHGHQMLDDLRKTTNPGYTG
IGRLKGLAELRGLEMGLLHGLE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory