Comparing Echvi_3411 FitnessBrowser__Cola:Echvi_3411 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2ctzA Crystal structure of o-acetyl homoserine sulfhydrylase from thermus thermophilus hb8
59% identity, 98% coverage: 6:432/436 of query aligns to 1:420/421 of 2ctzA
Q5SK88 O-acetyl-L-homoserine sulfhydrylase 1; OAH-sulfhydrylase 1; EC 2.5.1.- from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
59% identity, 98% coverage: 6:432/436 of query aligns to 1:420/421 of Q5SK88
O13326 Homocysteine synthase; O-acetylhomoserine sulfhydrylase; OAH SHL; OAH sulfhydrylase; EC 2.5.1.49 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
59% identity, 98% coverage: 8:433/436 of query aligns to 8:427/429 of O13326
8erbK Crystal structure of fub7 in complex with vinylglycine ketimine (see paper)
59% identity, 98% coverage: 8:434/436 of query aligns to 6:426/429 of 8erbK
8erjB Crystal structure of fub7 in complex with e-2-aminocrotonate (see paper)
59% identity, 98% coverage: 8:434/436 of query aligns to 5:425/428 of 8erjB
8erjA Crystal structure of fub7 in complex with e-2-aminocrotonate (see paper)
59% identity, 98% coverage: 8:434/436 of query aligns to 5:425/428 of 8erjA
7kb1C Complex of o-acety-l-homoserine aminocarboxypropyltransferase (mety) from thermotoga maritima and a key reaction intermediate (see paper)
54% identity, 99% coverage: 5:434/436 of query aligns to 4:425/428 of 7kb1C
7kb1A Complex of o-acety-l-homoserine aminocarboxypropyltransferase (mety) from thermotoga maritima and a key reaction intermediate (see paper)
54% identity, 99% coverage: 5:434/436 of query aligns to 4:425/428 of 7kb1A
8wkoA Crystal structure of o-acetylhomoserine sulfhydrylase from lactobacillus plantarum in the closed form
52% identity, 99% coverage: 5:435/436 of query aligns to 6:425/425 of 8wkoA
8ovhA Crystal structure of o-acetyl-l-homoserine sulfhydrolase from saccharomyces cerevisiae in complex with pyridoxal-5'-phosphate (see paper)
55% identity, 98% coverage: 8:435/436 of query aligns to 5:394/400 of 8ovhA
4hf8A Crystal structure of l-methionine gamma-lyase from citrobacter freundii with glycine (see paper)
39% identity, 99% coverage: 4:434/436 of query aligns to 4:394/396 of 4hf8A
4omaA The crystal structure of methionine gamma-lyase from citrobacter freundii in complex with l-cycloserine pyridoxal-5'-phosphate (see paper)
38% identity, 99% coverage: 4:434/436 of query aligns to 4:394/396 of 4omaA
3jwbA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with norleucine (see paper)
38% identity, 99% coverage: 4:434/436 of query aligns to 4:394/396 of 3jwbA
3jwaA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with methionine phosphinate (see paper)
38% identity, 99% coverage: 4:434/436 of query aligns to 4:394/396 of 3jwaA
3jw9A Crystal structure of l-methionine gamma-lyase from citrobacter freundii with s-ethyl-cysteine (see paper)
38% identity, 99% coverage: 4:434/436 of query aligns to 4:394/396 of 3jw9A
5m3zA Crystal structure of citrobacter freundii methionine gamma-lyase with c115h replacement in the complex with l-norleucine (see paper)
39% identity, 99% coverage: 5:434/436 of query aligns to 4:393/395 of 5m3zA
6egrA Crystal structure of citrobacter freundii methionine gamma-lyase with v358y replacement (see paper)
38% identity, 99% coverage: 4:434/436 of query aligns to 4:394/396 of 6egrA
Q5SJ58 O-acetyl-L-homoserine sulfhydrylase 2; OAH-sulfhydrylase 2; EC 2.5.1.- from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
40% identity, 99% coverage: 6:435/436 of query aligns to 1:412/412 of Q5SJ58
2cb1A Crystal structure of o-actetyl homoserine sulfhydrylase from thermus thermophilus hb8,oah2.
39% identity, 98% coverage: 6:433/436 of query aligns to 1:403/404 of 2cb1A
Sites not aligning to the query:
3mkjA Methionine gamma-lyase from citrobacter freundii with pyridoximine-5'- phosphate (see paper)
37% identity, 99% coverage: 4:434/436 of query aligns to 4:383/386 of 3mkjA
>Echvi_3411 FitnessBrowser__Cola:Echvi_3411
MSDHNFKFETLQLHAGHEPDSNTNSRAVPIYQTSSYVFNSAEHGANLFGLKEFGNIYTRI
MNPTNDVFEKRMAALEGGVAALAVSSGQAAQFIALSNILENGDNFVTSPFLYGGTYNQFK
VSFKRLGISARFASSEKAEDMEKLIDDRTKALYVETIGNPGFNVPDFEALSALSKKHDIP
LVVDNTFGAGGYLFRPLAHGAHIVVASATKWIGGHGTSIGGIIVDGGNYNWGNGKFPQFS
EPSEGYHGLNFWEVFGEGNPLGLPNIAFSIRARVEGLRDFGPAISPFNSFLLLQGLETLS
LRAERTVENALTLAKWLENHPQVATVSYPGLESHGHHTLAKKYLKKGFGGVLTFEVKGGK
EAGEKLVDSLQLISHLANVGDAKTLIIQPSATTHQQLSEKEQAAAGVTPGMLRISLGIEH
IDDICADLEQAFQKIG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory