Comparing Echvi_4084 FitnessBrowser__Cola:Echvi_4084 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 13 hits to proteins with known functional sites (download)
Q5SKW9 Glycine cleavage system H protein from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
51% identity, 98% coverage: 1:123/125 of query aligns to 1:124/128 of Q5SKW9
P16048 Glycine cleavage system H protein, mitochondrial from Pisum sativum (Garden pea) (Lathyrus oleraceus) (see paper)
50% identity, 95% coverage: 7:125/125 of query aligns to 41:160/165 of P16048
1htpA Refined structures at 2 angstroms and 2.2 angstroms of the two forms of the h-protein, a lipoamide-containing protein of the glycine decarboxylase complex (see paper)
50% identity, 95% coverage: 7:125/125 of query aligns to 7:126/131 of 1htpA
Sites not aligning to the query:
1hpcB Refined structures at 2 angstroms and 2.2 angstroms of the two forms of the h-protein, a lipoamide-containing protein of the glycine decarboxylase (see paper)
50% identity, 95% coverage: 7:125/125 of query aligns to 7:126/131 of 1hpcB
1hpcA Refined structures at 2 angstroms and 2.2 angstroms of the two forms of the h-protein, a lipoamide-containing protein of the glycine decarboxylase (see paper)
50% identity, 95% coverage: 7:125/125 of query aligns to 7:126/131 of 1hpcA
1dxmA Reduced form of the h protein from glycine decarboxylase complex (see paper)
50% identity, 95% coverage: 7:125/125 of query aligns to 7:126/131 of 1dxmA
Sites not aligning to the query:
P23434 Glycine cleavage system H protein, mitochondrial; Lipoic acid-containing protein from Homo sapiens (Human) (see 4 papers)
49% identity, 90% coverage: 8:119/125 of query aligns to 52:164/173 of P23434
Sites not aligning to the query:
P20821 Glycine cleavage system H protein, mitochondrial; Lipoic acid-containing protein from Bos taurus (Bovine) (see 3 papers)
48% identity, 90% coverage: 8:119/125 of query aligns to 52:164/173 of P20821
Sites not aligning to the query:
3ab9A Crystal structure of lipoylated e. Coli h-protein (reduced form) (see paper)
46% identity, 98% coverage: 2:123/125 of query aligns to 1:124/127 of 3ab9A
Q9HDV9 Putative glycine cleavage system H protein, mitochondrial; Glycine decarboxylase complex subunit H from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
43% identity, 94% coverage: 9:125/125 of query aligns to 47:164/169 of Q9HDV9
P11183 Glycine cleavage system H protein, mitochondrial; Lipoic acid-containing protein from Gallus gallus (Chicken) (see paper)
43% identity, 93% coverage: 8:123/125 of query aligns to 43:159/164 of P11183
Sites not aligning to the query:
A0A0H3JT43 Glycine cleavage system H-like protein; GcvH-L from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see paper)
31% identity, 78% coverage: 7:103/125 of query aligns to 1:96/110 of A0A0H3JT43
P0DN69 Glycine cleavage system H-like protein; GcvH-L from Streptococcus pyogenes serotype M5 (strain Manfredo) (see paper)
32% identity, 62% coverage: 24:101/125 of query aligns to 18:94/110 of P0DN69
Sites not aligning to the query:
>Echvi_4084 FitnessBrowser__Cola:Echvi_4084
MDFPKDLKYTKDHEWVKIEGETATIGITEFAQRELGDIVYVEVETVGETIETGEVFGTVE
AVKTVSDLFMPLNGEITEFNEELEGSPELVNDSPYEDGWMIKVKLEGALPDDLLSAEAYA
ELVGE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory