Comparing Echvi_4604 FitnessBrowser__Cola:Echvi_4604 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 17 hits to proteins with known functional sites (download)
1jg8D Crystal structure of threonine aldolase (low-specificity)
44% identity, 98% coverage: 1:328/335 of query aligns to 1:330/344 of 1jg8D
1lw5B X-ray structure of l-threonine aldolase (low-specificity) in complex with glycine (see paper)
44% identity, 97% coverage: 3:328/335 of query aligns to 2:329/343 of 1lw5B
1lw4B X-ray structure of l-threonine aldolase (low-specificity) in complex with l-allo-threonine (see paper)
44% identity, 97% coverage: 3:328/335 of query aligns to 2:329/343 of 1lw4B
O07051 L-allo-threonine aldolase; L-allo-TA; L-allo-threonine acetaldehyde-lyase; EC 4.1.2.49 from Aeromonas jandaei (see paper)
45% identity, 97% coverage: 3:328/335 of query aligns to 4:326/338 of O07051
3wgcB Aeromonas jandaei l-allo-threonine aldolase h128y/s292r double mutant (see paper)
45% identity, 97% coverage: 3:328/335 of query aligns to 3:323/333 of 3wgcB
3wgbD Crystal structure of aeromonas jandaei l-allo-threonine aldolase (see paper)
45% identity, 98% coverage: 3:331/335 of query aligns to 2:318/324 of 3wgbD
Q8RXU4 Low-specificity L-threonine aldolase 1; Threonine aldolase 1; EC 4.1.2.48 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
39% identity, 96% coverage: 2:323/335 of query aligns to 5:334/358 of Q8RXU4
3wlxA Crystal structure of low-specificity l-threonine aldolase from escherichia coli
40% identity, 97% coverage: 3:327/335 of query aligns to 2:320/331 of 3wlxA
4lnmA Structure of escherichia coli threonine aldolase in complex with serine (see paper)
40% identity, 97% coverage: 3:327/335 of query aligns to 2:320/331 of 4lnmA
4rjyA Crystal structure of e. Coli l-threonine aldolase in complex with a non-covalently uncleaved bound l-serine substrate (see paper)
40% identity, 97% coverage: 3:327/335 of query aligns to 2:320/332 of 4rjyA
4lnlA Structure of escherichia coli threonine aldolase in complex with allo- thr (see paper)
40% identity, 97% coverage: 3:327/335 of query aligns to 2:320/332 of 4lnlA
4lnjA Structure of escherichia coli threonine aldolase in unliganded form (see paper)
40% identity, 97% coverage: 3:327/335 of query aligns to 2:320/332 of 4lnjA
5vyeB Crystal structure of l-threonine aldolase from pseudomonas putida
25% identity, 98% coverage: 7:335/335 of query aligns to 8:339/344 of 5vyeB
O50584 Low specificity L-threonine aldolase; Low specificity L-TA; EC 4.1.2.48 from Pseudomonas sp. (strain NCIMB 10558) (see paper)
25% identity, 84% coverage: 54:335/335 of query aligns to 59:341/346 of O50584
1v72A Crystal structure of phenylserine aldolase from pseudomonas putida
25% identity, 88% coverage: 32:327/335 of query aligns to 35:337/345 of 1v72A
2jisB Human cysteine sulfinic acid decarboxylase (csad) in complex with plp.
27% identity, 47% coverage: 14:171/335 of query aligns to 102:269/487 of 2jisB
Sites not aligning to the query:
6zekA Crystal structure of mouse csad (see paper)
25% identity, 47% coverage: 14:171/335 of query aligns to 96:263/476 of 6zekA
Sites not aligning to the query:
>Echvi_4604 FitnessBrowser__Cola:Echvi_4604
MTIDLRSDTVTKPTEGMLAAMWSAEVGDDVLGEDPTVRALEIRLAAMFGMEAGMFCPSGT
MSNQIAIKLHAGQHKEVICHKDSHIYLYEGGGIMANAMTSVRLLEGHYGKVSPEAVEAAI
QPDDVHAPMTTLVSLENTMNKGGGSVYRLEEVTAIQEVCQAHQLKLHLDGARIFNALVAS
GEKAADWGNVFDTISVCLSKGLGCPMGSVLIGDKATIHQARRIRKAMGGGMRQVGFVAAA
GIYAMEHHIGRLGEDHRRARQVADILREHPHVEEVFPVETNIVIVRLRDISPKEMLSKLN
DKGIKAVQFGQDMVRFVTHLDITDDHLQAMEKRLK
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory