Comparing GFF1185 FitnessBrowser__Marino:GFF1185 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3jtxB Crystal structure of aminotransferase (np_283882.1) from neisseria meningitidis z2491 at 1.91 a resolution
50% identity, 99% coverage: 1:396/400 of query aligns to 1:393/393 of 3jtxB
2x5dD Crystal structure of a probable aminotransferase from pseudomonas aeruginosa (see paper)
28% identity, 92% coverage: 32:398/400 of query aligns to 20:378/380 of 2x5dD
1gdeA Crystal structure of pyrococcus protein a-1 e-form (see paper)
27% identity, 92% coverage: 32:399/400 of query aligns to 28:386/388 of 1gdeA
1gd9A Crystall structure of pyrococcus protein-a1 (see paper)
27% identity, 92% coverage: 32:399/400 of query aligns to 28:386/388 of 1gd9A
5wmhA Arabidopsis thaliana prephenate aminotransferase (see paper)
29% identity, 83% coverage: 1:331/400 of query aligns to 2:327/399 of 5wmhA
1o4sB Crystal structure of aspartate aminotransferase (tm1255) from thermotoga maritima at 1.90 a resolution (see paper)
26% identity, 98% coverage: 7:397/400 of query aligns to 13:384/384 of 1o4sB
5wmiA Arabidopsis thaliana prephenate aminotransferase mutant- t84v (see paper)
29% identity, 83% coverage: 1:331/400 of query aligns to 3:327/402 of 5wmiA
Sites not aligning to the query:
5wmlA Arabidopsis thaliana prephenate aminotransferase mutant- k306a (see paper)
29% identity, 83% coverage: 1:331/400 of query aligns to 3:328/404 of 5wmlA
Sites not aligning to the query:
6l1nA Substrate bound bacf structure from bacillus subtillis (see paper)
25% identity, 95% coverage: 13:391/400 of query aligns to 21:383/393 of 6l1nA
Sites not aligning to the query:
2o1bA Structure of aminotransferase from staphylococcus aureus
25% identity, 91% coverage: 32:394/400 of query aligns to 22:371/376 of 2o1bA
6l1oB Product bound bacf structure from bacillus subtillis (see paper)
25% identity, 90% coverage: 32:391/400 of query aligns to 35:384/392 of 6l1oB
Sites not aligning to the query:
1j32A Aspartate aminotransferase from phormidium lapideum
24% identity, 91% coverage: 33:395/400 of query aligns to 34:384/388 of 1j32A
6l1lB Apo-bacf structure from bacillus subtillis (see paper)
25% identity, 90% coverage: 32:391/400 of query aligns to 35:384/393 of 6l1lB
1bkgA Aspartate aminotransferase from thermus thermophilus with maleate (see paper)
28% identity, 81% coverage: 32:356/400 of query aligns to 34:351/382 of 1bkgA
1bjwA Aspartate aminotransferase from thermus thermophilus (see paper)
28% identity, 81% coverage: 32:356/400 of query aligns to 34:351/382 of 1bjwA
Sites not aligning to the query:
Q56232 Aspartate/prephenate aminotransferase; AspAT / PAT; Transaminase A; EC 2.6.1.1; EC 2.6.1.78 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 3 papers)
28% identity, 81% coverage: 32:356/400 of query aligns to 34:351/385 of Q56232
Sites not aligning to the query:
1b5oA Thermus thermophilus aspartate aminotransferase single mutant 1 (see paper)
28% identity, 81% coverage: 32:356/400 of query aligns to 34:351/382 of 1b5oA
1gc4A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with aspartate (see paper)
28% identity, 81% coverage: 32:356/400 of query aligns to 34:351/382 of 1gc4A
Sites not aligning to the query:
1gc3A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with tryptophan (see paper)
28% identity, 81% coverage: 32:356/400 of query aligns to 34:351/382 of 1gc3A
Sites not aligning to the query:
Q02635 Aspartate/prephenate aminotransferase; AspAT / PAT; Transaminase A; EC 2.6.1.1; EC 2.6.1.79 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
26% identity, 92% coverage: 32:397/400 of query aligns to 34:398/400 of Q02635
Sites not aligning to the query:
>GFF1185 FitnessBrowser__Marino:GFF1185
MNPNLDRLHPYPFEKLAKLKAGISVPDHLRPISLGIGEPKHPSPDFVKQVIANNLDKLAN
YPTTRGTDELREAISGWATRRFNLKAGSLSAANNIVPVNGTREAIFSLVQAVVDATKPAT
VVSPNPFYQVYEGAAFLAGATPVYIPCDGSNGFIPDFDSVPESIWQECQILFLCSPGNPS
GAVISREALTRVIALADKHDFIVASDECYSELYPEEGNAPEGLLQTCAAIGRDDYARCVV
FHSLSKRSNLPGLRSGFVAGDANILDGYLKYRTYHGCAMPIHNQLASIAAWSDEDHVREN
RAAYRAKFEAVVPILREVMDVDFPDAGFYLWPITPMDDETFARELSAQQNVHVLPGRYLS
RTVDGHNPGENRVRMALVAPLEECVEAAERIVEFVKANKP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory