Comparing GFF1395 FitnessBrowser__Marino:GFF1395 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 18 hits to proteins with known functional sites (download)
P0A9J8 Bifunctional chorismate mutase/prephenate dehydratase; Chorismate mutase-prephenate dehydratase; P-protein; EC 5.4.99.5; EC 4.2.1.51 from Escherichia coli (strain K12)
32% identity, 96% coverage: 11:361/365 of query aligns to 10:376/386 of P0A9J8
2qmxA The crystal structure of l-phe inhibited prephenate dehydratase from chlorobium tepidum tls (see paper)
35% identity, 73% coverage: 97:362/365 of query aligns to 4:275/278 of 2qmxA
3mwbA The crystal structure of prephenate dehydratase in complex with l-phe from arthrobacter aurescens to 2.0a
37% identity, 72% coverage: 99:360/365 of query aligns to 5:274/306 of 3mwbA
3mwbB The crystal structure of prephenate dehydratase in complex with l-phe from arthrobacter aurescens to 2.0a
37% identity, 72% coverage: 99:360/365 of query aligns to 5:271/303 of 3mwbB
6vh5D Crystal structure of prephenate dehydratase from brucella melitensis biovar abortus 2308 in complex with phenylalanine
31% identity, 73% coverage: 93:360/365 of query aligns to 5:276/282 of 6vh5D
7am0B Gqqa- a novel type of quorum quenching acylases (see paper)
30% identity, 73% coverage: 97:361/365 of query aligns to 4:270/278 of 7am0B
A0A0M0ELU2 Bifunctional N-acyl-homoserine lactone acylase/prephenate dehydratase; Bifunctional AHL acylase/PDT; Quorum quenching protein GqqA; EC 3.5.1.97; EC 4.2.1.51 from Komagataeibacter europaeus (Gluconacetobacter europaeus) (see paper)
30% identity, 73% coverage: 97:361/365 of query aligns to 7:273/281 of A0A0M0ELU2
Sites not aligning to the query:
3luyA Putative chorismate mutase from bifidobacterium adolescentis
27% identity, 72% coverage: 99:361/365 of query aligns to 8:284/326 of 3luyA
5j6fA Crystal structure of dah7ps-cm complex from geobacillus sp. With prephenate (see paper)
33% identity, 25% coverage: 7:96/365 of query aligns to 3:88/352 of 5j6fA
Sites not aligning to the query:
3tfcA 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e in complex with phosphoenolpyruvate (see paper)
35% identity, 24% coverage: 11:96/365 of query aligns to 1:77/343 of 3tfcA
Sites not aligning to the query:
3nvtA 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e (see paper)
37% identity, 24% coverage: 10:96/365 of query aligns to 1:78/345 of 3nvtA
Sites not aligning to the query:
7alzA Gqqa- a novel type of quorum quenching acylases (see paper)
33% identity, 28% coverage: 260:361/365 of query aligns to 82:186/194 of 7alzA
P39912 Protein AroA(G); EC 2.5.1.54; EC 5.4.99.5 from Bacillus subtilis (strain 168) (see paper)
32% identity, 26% coverage: 1:96/365 of query aligns to 1:90/358 of P39912
5jk5A Phenylalanine hydroxylase from dictyostelium - bh2 complex
35% identity, 21% coverage: 283:357/365 of query aligns to 5:83/400 of 5jk5A
Sites not aligning to the query:
5jk8A Phenylalanine hydroxylase from dictyostelium - bh2, norleucine complex
35% identity, 21% coverage: 283:357/365 of query aligns to 5:83/390 of 5jk8A
Sites not aligning to the query:
5gmuB Crystal structure of chorismate mutase like domain of bifunctional dahp synthase of bacillus subtilis in complex with chlorogenic acid (see paper)
33% identity, 23% coverage: 11:93/365 of query aligns to 8:86/87 of 5gmuB
6al9B Crystal structure of chorismate mutase from helicobacter pylori in complex with prephenate
31% identity, 21% coverage: 8:84/365 of query aligns to 5:75/91 of 6al9B
Sites not aligning to the query:
6al9A Crystal structure of chorismate mutase from helicobacter pylori in complex with prephenate
31% identity, 21% coverage: 8:84/365 of query aligns to 4:74/90 of 6al9A
Sites not aligning to the query:
>GFF1395 FitnessBrowser__Marino:GFF1395
MSDEQVRLGELRDEIDQLDQKIMELISARAACAQEVAHVKMTANPGQDVFFYRPEREAQV
LRRIKEQNPGPLSGEEMARLFREIMSACLALEKPMHIAFLGPIGTFTQAAALKHFGHSVV
SVPLPAIDAVFREVESGAAHYGVVPVENSTEGMINHTLDMFMSSPLKICGEVQLRIHHHL
LVSPKHGDQEITRIYSHQQSFAQCRQWLDTHRYGIERVTVSSNAEAARRAAEEPGTAAIA
GDMAAELYGLQKLANSIEDRPDNTTRFLIIGREEVPASGHDKSSILVSMRNKPGALYQLL
EPFHRHGLSLTRIETRPSPSGTWAYVFYIDFEGHMEDEQVRKVLAEVDEEAVELKRLGSY
PIGVL
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory