Comparing GFF1534 HP15_1498 phosphate acetyltransferase to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 10 hits to proteins with known functional sites (download)
Q8ZND6 Phosphate acetyltransferase; Phosphotransacetylase; EC 2.3.1.222; EC 2.3.1.8 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
52% identity, 98% coverage: 4:700/709 of query aligns to 15:711/714 of Q8ZND6
1xcoD Crystal structure of a phosphotransacetylase from bacillus subtilis in complex with acetylphosphate (see paper)
46% identity, 44% coverage: 384:698/709 of query aligns to 10:324/325 of 1xcoD
P38503 Phosphate acetyltransferase; Phosphotransacetylase; EC 2.3.1.8 from Methanosarcina thermophila (see 2 papers)
45% identity, 45% coverage: 380:698/709 of query aligns to 4:328/333 of P38503
Sites not aligning to the query:
2af3C Phosphotransacetylase from methanosarcina thermophila soaked with coenzyme a (see paper)
45% identity, 45% coverage: 380:698/709 of query aligns to 3:327/332 of 2af3C
6ioxA Crystal structure of porphyromonas gingivalis phosphotransacetylase in complex with acetyl-coa (see paper)
45% identity, 44% coverage: 387:698/709 of query aligns to 14:334/339 of 6ioxA
6zngF Maeb full-length acetyl-coa bound state (see paper)
33% identity, 51% coverage: 344:702/709 of query aligns to 382:747/753 of 6zngF
Sites not aligning to the query:
P76558 NADP-dependent malic enzyme; NADP-ME; EC 1.1.1.40 from Escherichia coli (strain K12) (see paper)
33% identity, 45% coverage: 380:699/709 of query aligns to 430:755/759 of P76558
Sites not aligning to the query:
7t85A Crystal structure of the n-terminal domain of the phosphate acetyltransferase from escherichia coli
29% identity, 23% coverage: 4:167/709 of query aligns to 15:152/173 of 7t85A
3uf6A The crystal structure of a possible phosphate acetyl/butaryl transferase (from listeria monocytogenes egd-e) in complex with cod (3'-dephosphocoenzyme a)
26% identity, 30% coverage: 469:680/709 of query aligns to 61:266/285 of 3uf6A
3u9eB The crystal structure of a possible phosphate acetyl/butaryl transferase (from listeria monocytogenes egd-e) in complex with coa.
26% identity, 30% coverage: 469:680/709 of query aligns to 63:268/288 of 3u9eB
Sites not aligning to the query:
>GFF1534 HP15_1498 phosphate acetyltransferase
MDSGLTSVCLGLLRALERVGVSVGFYKPFCQAVHRAESMHNAGQDSSVAFVRASSHLNPP
DPIALKEAQQLLNRGKADYLLETVVGEYQKVARDVDVVIIEGLVPDRSEAYIARLNVEVA
RNLGSEVILVSTPKDLDARQLDEELDFSSRLFASPSDPDVIGVILNKVGEPEQSGLEPRS
NNNHPAPVTVDYQTECTVFSEGRFHLLAEIPWQADLLAPRVSDIARELGLPVLNEGQMHA
RRVQKVSVCARSIRNMTETLRPGTLLVTPGDREDIVVATAVAALNGVPLAGLMLTGGLIP
DQRVITLCHRALETGLPVLGSDANTYETAHMLANLSAAIPIDDPNRIEKAMEAVATRIDT
NWLQQHLKVARQDRLSPPAFRYQLSERARAANKRIILPEGSEPRTVQAAIICHQRRLARC
ALIGNAAEIKRVADSQDLELPGDIEIIDPGEVRQRYVAPMVELRKHKGLTSDMAEAMLED
NVVLGTMMVALDEADGLVSGAIHTTANTVRPALQLIKTHEHAKVVSSVFFMLLPQQVVVY
GDCAINPDPNAEELADIAIQSAESAEAFGIEPLVAMISYSTGESGSGQDVEKVREATRIA
RERRPDLLIDGPLQYDAAAIESVARSKAPDSKVAGKATVFVFPDLNTGNTTYKAVQRSAN
VVSVGPMLQGLRKPVNDLSRGALVEDIVFTVALTAVQAKQVESAGPDQE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory