Comparing GFF1751 FitnessBrowser__psRCH2:GFF1751 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4yslA Crystal structure of sdoa from pseudomonas putida in complex with glutathione (see paper)
64% identity, 100% coverage: 2:287/287 of query aligns to 6:294/294 of 4yslA
4yskA Crystal structure of apo-form sdoa from pseudomonas putida (see paper)
64% identity, 100% coverage: 2:287/287 of query aligns to 6:294/294 of 4yskA
4efzA Crystal structure of a hypothetical metallo-beta-lactamase from burkholderia pseudomallei
63% identity, 99% coverage: 5:287/287 of query aligns to 7:295/295 of 4efzA
4ysbA Crystal structure of ethe1 from myxococcus xanthus (see paper)
34% identity, 91% coverage: 8:267/287 of query aligns to 6:224/225 of 4ysbA
O95571 Persulfide dioxygenase ETHE1, mitochondrial; Ethylmalonic encephalopathy protein 1; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Homo sapiens (Human) (see 4 papers)
30% identity, 92% coverage: 5:267/287 of query aligns to 25:248/254 of O95571
Sites not aligning to the query:
4chlB Human ethylmalonic encephalopathy protein 1 (hethe1) (see paper)
30% identity, 92% coverage: 5:267/287 of query aligns to 9:232/237 of 4chlB
5ve5A Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (c314s) from burkholderia phytofirmans in complex with glutathione (see paper)
31% identity, 93% coverage: 8:273/287 of query aligns to 9:236/350 of 5ve5A
Q9C8L4 Persulfide dioxygenase ETHE1 homolog, mitochondrial; Glyoxalase II; Glx II; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
28% identity, 77% coverage: 48:267/287 of query aligns to 88:285/294 of Q9C8L4
2gcuA X-ray structure of gene product from arabidopsis thaliana at1g53580 (see paper)
26% identity, 93% coverage: 1:267/287 of query aligns to 1:236/244 of 2gcuA
3tp9A Crystal structure of alicyclobacillus acidocaldarius protein with beta-lactamase and rhodanese domains
29% identity, 70% coverage: 4:204/287 of query aligns to 4:198/473 of 3tp9A
3r2uB 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
26% identity, 69% coverage: 6:204/287 of query aligns to 8:189/336 of 3r2uB
Sites not aligning to the query:
O24496 Hydroxyacylglutathione hydrolase cytoplasmic; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
26% identity, 95% coverage: 15:287/287 of query aligns to 12:246/258 of O24496
Sites not aligning to the query:
2q42A Ensemble refinement of the protein crystal structure of glyoxalase ii from arabidopsis thaliana gene at2g31350 (see paper)
26% identity, 67% coverage: 15:206/287 of query aligns to 12:171/254 of 2q42A
Q9SID3 Hydroxyacylglutathione hydrolase 2, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
27% identity, 67% coverage: 15:206/287 of query aligns to 82:241/324 of Q9SID3
2xf4A Crystal structure of salmonella enterica serovar typhimurium ycbl (see paper)
32% identity, 54% coverage: 49:204/287 of query aligns to 35:192/210 of 2xf4A
3r2uA 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
23% identity, 77% coverage: 6:227/287 of query aligns to 6:222/348 of 3r2uA
7l0bA Crystal structure of hydroxyacyl glutathione hydrolase (glob) from staphylococcus aureus, apoenzyme (see paper)
28% identity, 54% coverage: 49:204/287 of query aligns to 34:185/202 of 7l0bA
7ev5A Crystal structure of bleg-1 b3 metallo-beta-lactamase (see paper)
29% identity, 54% coverage: 49:204/287 of query aligns to 33:191/209 of 7ev5A
Q16775 Hydroxyacylglutathione hydrolase, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Homo sapiens (Human) (see paper)
26% identity, 68% coverage: 13:206/287 of query aligns to 58:223/308 of Q16775
Sites not aligning to the query:
1qh5B Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione (see paper)
26% identity, 68% coverage: 13:206/287 of query aligns to 10:175/260 of 1qh5B
Sites not aligning to the query:
>GFF1751 FitnessBrowser__psRCH2:GFF1751
MNAHVEAFFDPATFTYSYVVSDPVTQQCAVIDSVLDYDPASGRTSHATAERLVDYVRAQG
LTVQWLLETHVHADHLSAAPYLKQQLGGRLAIGDRITVVQDTFGKLFNAGSEFATDGRQF
DHLFHDGDTFQVGNIQAHAIHTPGHTPACMTYVIGDAAFVGDTLFMPDYGTARCDFPGGD
ARTLYQSIQKLFTLPDSTRVFMCHDYKAPGREEFLYETTIAAERELNVHVHAGITEEEFV
AMRTARDATLGMPTLILPSVQINMRGGELPEPESNGTRYLKIPLDVL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory