Comparing GFF1863 FitnessBrowser__Marino:GFF1863 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4omaA The crystal structure of methionine gamma-lyase from citrobacter freundii in complex with l-cycloserine pyridoxal-5'-phosphate (see paper)
44% identity, 94% coverage: 14:403/413 of query aligns to 1:393/396 of 4omaA
3jwbA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with norleucine (see paper)
44% identity, 94% coverage: 14:403/413 of query aligns to 1:393/396 of 3jwbA
3jwaA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with methionine phosphinate (see paper)
44% identity, 94% coverage: 14:403/413 of query aligns to 1:393/396 of 3jwaA
3jw9A Crystal structure of l-methionine gamma-lyase from citrobacter freundii with s-ethyl-cysteine (see paper)
44% identity, 94% coverage: 14:403/413 of query aligns to 1:393/396 of 3jw9A
6egrA Crystal structure of citrobacter freundii methionine gamma-lyase with v358y replacement (see paper)
44% identity, 94% coverage: 14:403/413 of query aligns to 1:393/396 of 6egrA
4hf8A Crystal structure of l-methionine gamma-lyase from citrobacter freundii with glycine (see paper)
44% identity, 94% coverage: 14:403/413 of query aligns to 1:393/396 of 4hf8A
5m3zA Crystal structure of citrobacter freundii methionine gamma-lyase with c115h replacement in the complex with l-norleucine (see paper)
44% identity, 92% coverage: 22:403/413 of query aligns to 8:392/395 of 5m3zA
3mkjA Methionine gamma-lyase from citrobacter freundii with pyridoximine-5'- phosphate (see paper)
43% identity, 94% coverage: 14:403/413 of query aligns to 1:382/386 of 3mkjA
P9WGB5 O-succinylhomoserine sulfhydrylase; OSH sulfhydrylase; OSHS sulfhydrylase; EC 2.5.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
42% identity, 96% coverage: 6:402/413 of query aligns to 4:405/406 of P9WGB5
5dx5A Crystal structure of methionine gamma-lyase from clostridium sporogenes (see paper)
41% identity, 95% coverage: 15:405/413 of query aligns to 2:397/399 of 5dx5A
4iyoB Crystal structure of cystathionine gamma lyase from xanthomonas oryzae pv. Oryzae (xometc) in complex with e-site serine, a-site serine, a- site external aldimine structure with aminoacrylate and a-site iminopropionate intermediates (see paper)
45% identity, 93% coverage: 19:402/413 of query aligns to 2:380/381 of 4iyoB
4iy7B Crystal structure of cystathionine gamma lyase (xometc) from xanthomonas oryzae pv. Oryzae in complex with e-site serine, a-site external aldimine structure with serine and a-site external aldimine structure with aminoacrylate intermediates (see paper)
45% identity, 93% coverage: 19:402/413 of query aligns to 2:380/381 of 4iy7B
4iy7A Crystal structure of cystathionine gamma lyase (xometc) from xanthomonas oryzae pv. Oryzae in complex with e-site serine, a-site external aldimine structure with serine and a-site external aldimine structure with aminoacrylate intermediates (see paper)
45% identity, 93% coverage: 19:402/413 of query aligns to 2:380/381 of 4iy7A
4ixzA Native structure of cystathionine gamma lyase (xometc) from xanthomonas oryzae pv. Oryzae at ph 9.0 (see paper)
45% identity, 93% coverage: 19:402/413 of query aligns to 2:380/381 of 4ixzA
4iyoD Crystal structure of cystathionine gamma lyase from xanthomonas oryzae pv. Oryzae (xometc) in complex with e-site serine, a-site serine, a- site external aldimine structure with aminoacrylate and a-site iminopropionate intermediates (see paper)
45% identity, 95% coverage: 19:409/413 of query aligns to 2:384/384 of 4iyoD
4ixsB Native structure of xometc at ph 5.2 (see paper)
44% identity, 93% coverage: 19:402/413 of query aligns to 1:371/372 of 4ixsB
1pg8A Crystal structure of l-methionine alpha-, gamma-lyase
40% identity, 89% coverage: 37:404/413 of query aligns to 23:396/398 of 1pg8A
P13254 L-methionine gamma-lyase; MGL; Homocysteine desulfhydrase; L-methioninase; EC 4.4.1.11; EC 4.4.1.2 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
40% identity, 89% coverage: 37:404/413 of query aligns to 23:396/398 of P13254
5x30C Crystal structure of pseudomonas putida methionine gamma-lyase c116h mutant with l-homocysteine intermediates. (see paper)
40% identity, 89% coverage: 37:404/413 of query aligns to 18:391/393 of 5x30C
3vk3A Crystal structure of l-methionine gamma-lyase from pseudomonas putida c116h mutant complexed with l-methionine (see paper)
40% identity, 89% coverage: 37:404/413 of query aligns to 22:395/397 of 3vk3A
>GFF1863 FitnessBrowser__Marino:GFF1863
MTFRREETVWIPESDLDGMSVDTLAVRAGQIRTGQLEHSDAIFPTSSFVYGSAAQAAARF
GGEEPGNIYSRFTNPTVQAFEGRIAAMEGGERAVATASGMSAILSTCMALLKSGDHVICS
RGVFGTTNVLFQKYMARFGVETTFVSLTDMEEWQASIRSETRMLFIETPSNPLCEVADME
ILGQLARDNDALFVVDNCFCTPVLQRPLEQGADIVIHSATKYLDGQGRCVGGVVVGSEKM
MEEVYGFLRSAGPTMSPFNAWVFQKGLETLPIRMRAHCDNALELALWLEQQPAVERVFYA
GLQSHPQHELAKKQQTGFGGVLSFQLKGAREEAWRFIDGTRMISITANLGDVKTTITHPA
TTTHGRLSPEDKARAGITENLIRISVGIEAVEDLKTDLERGFQALRNESTDNV
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory