Comparing GFF1877 FitnessBrowser__psRCH2:GFF1877 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
7mh7A Crystal structure of NAD kinase from pseudomonas aeruginosa pao1
86% identity, 98% coverage: 2:291/295 of query aligns to 1:290/290 of 7mh7A
P0A7B3 NAD kinase; ATP-dependent NAD kinase; EC 2.7.1.23 from Escherichia coli (strain K12) (see paper)
48% identity, 98% coverage: 3:291/295 of query aligns to 4:291/292 of P0A7B3
P9WHV7 NAD kinase; ATP-dependent NAD kinase; Poly(P)-dependent NAD kinase; PPNK; EC 2.7.1.23 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
31% identity, 89% coverage: 1:262/295 of query aligns to 1:274/307 of P9WHV7
3afoA Crystal structure of yeast nadh kinase complexed with nadh
32% identity, 81% coverage: 49:287/295 of query aligns to 97:342/360 of 3afoA
1y3iA Crystal structure of mycobacterium tuberculosis NAD kinase-NAD complex (see paper)
35% identity, 65% coverage: 70:262/295 of query aligns to 12:203/231 of 1y3iA
O13863 Uncharacterized kinase C1B1.02c; EC 2.7.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
27% identity, 90% coverage: 28:292/295 of query aligns to 235:516/537 of O13863
Sites not aligning to the query:
Q9P7K3 Uncharacterized kinase C24B10.02c; EC 2.7.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
27% identity, 77% coverage: 64:290/295 of query aligns to 176:409/449 of Q9P7K3
Sites not aligning to the query:
1z0zA Crystal structure of a NAD kinase from archaeoglobus fulgidus in complex with NAD (see paper)
31% identity, 64% coverage: 61:248/295 of query aligns to 38:212/249 of 1z0zA
1z0sA Crystal structure of an NAD kinase from archaeoglobus fulgidus in complex with atp (see paper)
31% identity, 64% coverage: 61:248/295 of query aligns to 38:212/249 of 1z0sA
Sites not aligning to the query:
1suwA Crystal structure of a NAD kinase from archaeoglobus fulgidus in complex with its substrate and product: insights into the catalysis of NAD kinase (see paper)
31% identity, 64% coverage: 61:248/295 of query aligns to 38:212/249 of 1suwA
O30297 NAD kinase; ATP-dependent NAD kinase; EC 2.7.1.23 from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) (see paper)
31% identity, 64% coverage: 61:248/295 of query aligns to 38:212/249 of O30297
5ejiA Crystal structure of NAD kinase w78f mutant from listeria monocytogenes in complex with NADP/mn++/ppi
30% identity, 50% coverage: 64:210/295 of query aligns to 37:180/260 of 5ejiA
5dhuA Crystal structure of NAD kinase 1 from listeria monocytogenes in complex with a novel inhibitor (see paper)
30% identity, 50% coverage: 64:210/295 of query aligns to 37:183/263 of 5dhuA
Sites not aligning to the query:
5dhtA Crystal structure of NAD kinase 1 from listeria monocytogenes in complex with a novel inhibitor (see paper)
30% identity, 50% coverage: 64:210/295 of query aligns to 37:183/263 of 5dhtA
Sites not aligning to the query:
5dhsA Crystal structure of NAD kinase 1 from listeria monocytogenes in complex with a novel inhibitor (see paper)
30% identity, 50% coverage: 64:210/295 of query aligns to 37:183/263 of 5dhsA
Sites not aligning to the query:
5dhrA Crystal structure of NAD kinase 1 from listeria monocytogenes in complex with a novel inhibitor (see paper)
30% identity, 50% coverage: 64:210/295 of query aligns to 37:183/263 of 5dhrA
Sites not aligning to the query:
5dhqA Crystal structure of NAD kinase 1 from listeria monocytogenes in complex with a novel inhibitor (see paper)
30% identity, 50% coverage: 64:210/295 of query aligns to 37:183/263 of 5dhqA
Sites not aligning to the query:
5dhpA Crystal structure of NAD kinase 1 from listeria monocytogenes in complex with a novel inhibitor (see paper)
30% identity, 50% coverage: 64:210/295 of query aligns to 37:183/263 of 5dhpA
Sites not aligning to the query:
6rbpA Crystal structure of NAD kinase 1 from listeria monocytogenes in complexe with an adenine derivative (see paper)
30% identity, 50% coverage: 64:210/295 of query aligns to 37:180/260 of 6rbpA
6rc1A Crystal structure of NAD kinase 1 from listeria monocytogenes in complexe with an adenine derivative (see paper)
30% identity, 50% coverage: 64:210/295 of query aligns to 37:180/259 of 6rc1A
>GFF1877 FitnessBrowser__psRCH2:GFF1877
MEQFRNIGIIGRLGSSQVLDTIRRLKRFLVERHLHVILEENIAEVLPGHGMQTSSRQRLG
ESCDLVIVVGGDGSLLGAARAMAKHRVPVLGINRGSLGFLTDIRPDELEEKVAEVLNGQY
TLENRFLLEAQARRFDEPIGEGDALNDVVLHPGKSTRMIEFELYIDGQFVCSQKADGLIV
ATPTGSTAYSLSAGGPIMHPRLDAIVVVPMYPHTLSSRPIVVDGNSELKIVVSPNMQIYP
QVSCDGQNHFTCAPGDTVTVRKKPQKLHLIHPLDHNYYEVCRTKLGWGSRLGGGD
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory