Comparing GFF1919 FitnessBrowser__WCS417:GFF1919 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 8 hits to proteins with known functional sites (download)
P0A6K1 Diaminopimelate epimerase; DAP epimerase; PLP-independent amino acid racemase; EC 5.1.1.7 from Escherichia coli (strain K12) (see paper)
27% identity, 72% coverage: 67:298/324 of query aligns to 43:245/274 of P0A6K1
Sites not aligning to the query:
Q8NP73 Diaminopimelate epimerase; DAP epimerase; PLP-independent amino acid racemase; EC 5.1.1.7 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)
30% identity, 70% coverage: 86:311/324 of query aligns to 74:263/277 of Q8NP73
Sites not aligning to the query:
3ejxD Crystal structure of diaminopimelate epimerase from arabidopsis thaliana in complex with ll-azidap (see paper)
25% identity, 68% coverage: 80:298/324 of query aligns to 74:272/301 of 3ejxD
Sites not aligning to the query:
3ekmA Crystal structure of diaminopimelate epimerase form arabidopsis thaliana in complex with irreversible inhibitor dl-azidap (see paper)
25% identity, 68% coverage: 80:298/324 of query aligns to 60:258/287 of 3ekmA
Sites not aligning to the query:
5m47A Crystal structure of dapf from corynebacterium glutamicum in complex with d,l-diaminopimelate (see paper)
30% identity, 70% coverage: 86:311/324 of query aligns to 74:263/280 of 5m47A
Sites not aligning to the query:
2gkjA Crystal structure of diaminopimelate epimerase in complex with an irreversible inhibitor dl-azidap (see paper)
27% identity, 72% coverage: 67:298/324 of query aligns to 43:245/274 of 2gkjA
Sites not aligning to the query:
2gkeA Crystal structure of diaminopimelate epimerase in complex with an irreversible inhibitor ll-azidap (see paper)
27% identity, 72% coverage: 67:298/324 of query aligns to 43:245/274 of 2gkeA
Sites not aligning to the query:
P44859 Diaminopimelate epimerase; DAP epimerase; PLP-independent amino acid racemase; EC 5.1.1.7 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 2 papers)
27% identity, 72% coverage: 67:298/324 of query aligns to 43:245/274 of P44859
Sites not aligning to the query:
>GFF1919 FitnessBrowser__WCS417:GFF1919
MTLFYDARGNMYGVVSPASLRDAGIAVPESAELAARTRSNWTSAAIASECSWGSLPRPAS
AKSHRCDGLLVGPFQAEPPFDLMIVNTDGSLAERSGNGLTIFAQALTDQGLLSGACELRV
HHDKSDAVSPVSTWVEPAIREQVAGFWLELGVPGFGPEVVGAQMEVDETELSHVSELAAI
NPQWAASQFVRVGNPHCVTLVEQVSALPDNTQMQQPALYEPLKTIAFAPPAGGGRPCPAG
VNLQWAARQPGNRIIARVFERGEGPTASSGTSASAVACAAWRAGWVESGEVAVVMPGGIA
PVRLHTQAETLLSVSLFGTAQLQE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory