SitesBLAST
Comparing GFF2134 FitnessBrowser__Phaeo:GFF2134 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8b7sA Crystal structure of the chloramphenicol-inactivating oxidoreductase from novosphingobium sp (see paper)
36% identity, 95% coverage: 4:528/551 of query aligns to 6:450/458 of 8b7sA
- binding flavin-adenine dinucleotide: I10 (≠ V8), G11 (= G9), G12 (≠ A10), G13 (= G11), S14 (= S12), A15 (= A13), L34 (≠ I31), E35 (= E32), A36 (≠ H33), W47 (= W59), P65 (= P77), A66 (≠ R78), G67 (= G79), K68 (= K80), V69 (= V81), S74 (≠ M91), A178 (= A217), F179 (≠ L218), V180 (≠ A219), S213 (≠ A252), A214 (= A253), G215 (≠ S254), A218 (≠ N257), T270 (= T330), Y391 (= Y467), H392 (= H468), D423 (= D501), A424 (≠ S502), I435 (≠ L513), N436 (= N514), A439 (≠ S517)
5nccA Structure of fatty acid photodecarboxylase in complex with fad and palmitic acid (see paper)
35% identity, 96% coverage: 4:531/551 of query aligns to 25:572/578 of 5nccA
- active site: R347 (≠ A319), L420 (≠ V381), I421 (≠ G382), S507 (≠ A466), A509 (≠ H468), G552 (= G511), Q553 (≠ N512)
- binding flavin-adenine dinucleotide: G30 (= G9), G31 (≠ A10), G32 (= G11), T33 (≠ S12), A34 (= A13), L53 (≠ I31), E54 (= E32), A55 (≠ H33), F74 (≠ N53), W80 (= W59), A98 (≠ P77), R99 (= R78), G100 (= G79), R101 (≠ K80), L102 (≠ V81), G105 (= G84), S106 (= S85), S107 (= S86), N110 (= N89), A111 (≠ G90), T112 (≠ M91), L113 (≠ V92), M207 (≠ T189), A236 (≠ L218), A237 (= A219), V238 (≠ R220), C277 (≠ A252), A278 (= A253), G279 (≠ S254), H282 (≠ N257), L286 (= L261), N508 (≠ Y467), D542 (= D501), A543 (≠ S502), Q553 (≠ N512), T554 (≠ L513), G555 (≠ N514), V558 (≠ S517)
3ljpA Crystal structure of choline oxidase v464a mutant (see paper)
37% identity, 96% coverage: 4:532/551 of query aligns to 15:530/530 of 3ljpA
- active site: I333 (≠ S340), P377 (≠ V381), N378 (≠ G382), A464 (= A466), H466 (= H468), V509 (≠ G511), N510 (= N512)
- binding dihydroflavine-adenine dinucleotide: V19 (= V8), G20 (= G9), G21 (≠ A10), G22 (= G11), S23 (= S12), A24 (= A13), E44 (= E32), A45 (≠ H33), W71 (= W59), R89 (= R78), A90 (≠ G79), K91 (= K80), V92 (= V81), G95 (= G84), C96 (≠ S85), S97 (= S86), H99 (≠ I88), N100 (= N89), S101 (≠ G90), C102 (≠ M91), I103 (≠ V92), L230 (= L218), R231 (vs. gap), A232 (= A219), S268 (≠ A252), T269 (≠ A253), G270 (≠ S254), D273 (≠ N257), Y465 (= Y467), H466 (= H468), D499 (= D501), A500 (≠ S502), N510 (= N512), P511 (≠ L513), N512 (= N514), V515 (≠ S517)
A0A248QE08 Fatty acid photodecarboxylase, chloroplastic; CvFAP; EC 4.1.1.106 from Chlorella variabilis (Green alga) (see paper)
35% identity, 96% coverage: 4:531/551 of query aligns to 85:639/654 of A0A248QE08
- TA 93:94 (≠ SA 12:13) binding
- E114 (= E32) binding
- L162 (≠ V81) binding
- S166 (= S85) binding
- NATL 170:173 (≠ NGMV 89:92) binding
- V298 (≠ A219) binding
- C432 (≠ F338) binding
- R451 (≠ H358) binding
- Y466 (vs. gap) binding
- Q486 (≠ H380) binding
- G622 (≠ N514) binding
6yrvAAA structure of fap after illumination at 100k (see paper)
35% identity, 96% coverage: 4:531/551 of query aligns to 9:563/573 of 6yrvAAA
- binding carbon dioxide: R375 (≠ H358), S498 (≠ A466), N499 (≠ Y467)
- binding flavin-adenine dinucleotide: G14 (= G9), G15 (≠ A10), G16 (= G11), T17 (≠ S12), A18 (= A13), L37 (≠ I31), E38 (= E32), A39 (≠ H33), F58 (≠ N53), W64 (= W59), A82 (≠ P77), R83 (= R78), G84 (= G79), R85 (≠ K80), L86 (≠ V81), G89 (= G84), S90 (= S85), S91 (= S86), T93 (≠ I88), N94 (= N89), A95 (≠ G90), T96 (≠ M91), L97 (≠ V92), M191 (≠ T189), A220 (= A217), A221 (≠ L218), V222 (≠ A219), C264 (≠ A252), A265 (= A253), G266 (≠ S254), H269 (≠ N257), L273 (= L261), N499 (≠ Y467), D533 (= D501), A534 (≠ S502), Q544 (≠ N512), T545 (≠ L513), G546 (≠ N514), V549 (≠ S517)
- binding heptadecane: A52 (≠ G46), T55 (≠ S49), F58 (≠ N53), I324 (vs. gap), S353 (= S335), T354 (≠ N336), V377 (≠ L360), G379 (vs. gap), M380 (≠ I362), A381 (= A363), G386 (= G368), T389 (≠ A371), Y390 (vs. gap), F393 (vs. gap), W403 (vs. gap), T408 (≠ Q378), Q410 (≠ H380)
4mjwA Crystal structure of choline oxidase in complex with the reaction product glycine betaine (see paper)
37% identity, 96% coverage: 4:532/551 of query aligns to 15:530/532 of 4mjwA
- active site: I333 (≠ S340), P377 (≠ V381), N378 (≠ G382), V464 (≠ A466), H466 (= H468), V509 (≠ G511), N510 (= N512)
- binding flavin-adenine dinucleotide: G20 (= G9), G21 (≠ A10), G22 (= G11), S23 (= S12), A24 (= A13), E44 (= E32), A45 (≠ H33), W71 (= W59), A88 (≠ P77), R89 (= R78), A90 (≠ G79), K91 (= K80), V92 (= V81), G95 (= G84), C96 (≠ S85), S97 (= S86), H99 (≠ I88), N100 (= N89), S101 (≠ G90), C102 (≠ M91), I103 (≠ V92), L230 (= L218), R231 (vs. gap), A232 (= A219), S268 (≠ A252), T269 (≠ A253), G270 (≠ S254), D273 (≠ N257), L277 (= L261), Y465 (= Y467), H466 (= H468), D499 (= D501), A500 (≠ S502), N510 (= N512), P511 (≠ L513), N512 (= N514), V515 (≠ S517)
2jbvA Crystal structure of choline oxidase reveals insights into the catalytic mechanism (see paper)
37% identity, 95% coverage: 4:528/551 of query aligns to 15:526/527 of 2jbvA
- active site: I333 (≠ S340), P377 (≠ V381), N378 (≠ G382), V464 (≠ A466), H466 (= H468), V509 (≠ G511), N510 (= N512)
- binding [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[(4aS,10aR)-7,8-dimethyl-2,4-dioxo-1,3,4,4a,5,10a-hexahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate: G20 (= G9), G21 (≠ A10), G22 (= G11), S23 (= S12), A24 (= A13), E44 (= E32), A45 (≠ H33), W71 (= W59), R89 (= R78), A90 (≠ G79), V92 (= V81), G95 (= G84), C96 (≠ S85), S97 (= S86), H99 (≠ I88), N100 (= N89), S101 (≠ G90), C102 (≠ M91), I103 (≠ V92), L230 (= L218), R231 (vs. gap), A232 (= A219), S268 (≠ A252), T269 (≠ A253), G270 (≠ S254), D273 (≠ N257), V464 (≠ A466), Y465 (= Y467), H466 (= H468), D499 (= D501), A500 (≠ S502), N510 (= N512), P511 (≠ L513), N512 (= N514), V515 (≠ S517)
4ha6A Crystal structure of pyridoxine 4-oxidase - pyridoxamine complex (see paper)
32% identity, 95% coverage: 2:523/551 of query aligns to 1:499/508 of 4ha6A