Comparing GFF2135 FitnessBrowser__Phaeo:GFF2135 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q9HTJ1 NAD/NADP-dependent betaine aldehyde dehydrogenase; BADH; EC 1.2.1.8 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
56% identity, 98% coverage: 12:485/485 of query aligns to 10:490/490 of Q9HTJ1
4cazA Crystal structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa in complex with nadh
56% identity, 98% coverage: 12:485/485 of query aligns to 9:489/489 of 4cazA
2woxA Betaine aldehyde dehydrogenase from pseudomonas aeruginosa with NAD(p) h-catalytic thiol adduct. (see paper)
56% identity, 98% coverage: 12:485/485 of query aligns to 9:489/489 of 2woxA
2wmeA Crystallographic structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa (see paper)
56% identity, 98% coverage: 12:485/485 of query aligns to 9:489/489 of 2wmeA
6wsbA Crystal structure of a betaine aldehyde dehydrogenase from burkholderia pseudomallei bound to cofactor NAD (see paper)
54% identity, 98% coverage: 12:485/485 of query aligns to 9:488/489 of 6wsbA
8vr1A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (ctp bound)
55% identity, 98% coverage: 12:485/485 of query aligns to 8:488/488 of 8vr1A
8vr0A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (gmp bound)
55% identity, 98% coverage: 12:485/485 of query aligns to 8:488/488 of 8vr0A
8vqzA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (cmp bound)
55% identity, 98% coverage: 12:485/485 of query aligns to 8:488/488 of 8vqzA
8vqwC Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (coa bound)
55% identity, 98% coverage: 12:485/485 of query aligns to 8:488/488 of 8vqwC
8vj3A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (fad bound)
55% identity, 98% coverage: 12:485/485 of query aligns to 8:488/488 of 8vj3A
8uzoA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (adp bound)
55% identity, 98% coverage: 12:485/485 of query aligns to 8:488/488 of 8uzoA
8uznA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (amp bound)
55% identity, 98% coverage: 12:485/485 of query aligns to 8:488/488 of 8uznA
8uzmA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (NADPH bound)
55% identity, 98% coverage: 12:485/485 of query aligns to 8:488/488 of 8uzmA
8uzkA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (NADP+ bound)
55% identity, 98% coverage: 12:485/485 of query aligns to 8:488/488 of 8uzkA
8skfA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (lattice translocation disorder)
55% identity, 98% coverage: 12:485/485 of query aligns to 17:497/497 of 8skfA
P49189 4-trimethylaminobutyraldehyde dehydrogenase; TMABA-DH; TMABALDH; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; Formaldehyde dehydrogenase; Gamma-aminobutyraldehyde dehydrogenase; R-aminobutyraldehyde dehydrogenase; EC 1.2.1.47; EC 1.2.1.3; EC 1.2.1.46; EC 1.2.1.19 from Homo sapiens (Human) (see 2 papers)
55% identity, 94% coverage: 32:485/485 of query aligns to 35:494/494 of P49189
Sites not aligning to the query:
6vr6D Structure of aldh9a1 complexed with NAD+ in space group p1 (see paper)
55% identity, 94% coverage: 32:485/485 of query aligns to 34:493/493 of 6vr6D
1bpwA Betaine aldehyde dehydrogenase from cod liver (see paper)
51% identity, 95% coverage: 27:485/485 of query aligns to 39:503/503 of 1bpwA
P56533 4-trimethylaminobutyraldehyde dehydrogenase; TMABA-DH; TMABADH; Aldehyde dehydrogenase family 9 member A1; Betaine aldehyde dehydrogenase; BADH; EC 1.2.1.47; EC 1.2.1.3 from Gadus morhua subsp. callarias (Baltic cod) (Gadus callarias) (see paper)
51% identity, 95% coverage: 27:485/485 of query aligns to 39:503/503 of P56533
6vwfA Structure of aldh9a1 complexed with NAD+ in space group c222 (see paper)
49% identity, 94% coverage: 32:485/485 of query aligns to 35:450/450 of 6vwfA
>GFF2135 FitnessBrowser__Phaeo:GFF2135
MTHPAQPKASHFINGEYVEDTAGTPIPVIYAATGEQIATVHAATPAIVEQALSTAKAAQK
AWARMTGTERGRILRRAADIMRERNHDLSVLETYDTGKPLQETLVADATSGADALEYFGG
LAASLTGEHIPLGEDWVYTKREALGLCVGIGAWNYPTQIACWKGAPALACGNSMVFKPSE
TTPLCALKVAEILIEAGAPAGVFNVVQGMGEVGGALVTDPRVDKVSLTGSVPTGKKVYAA
AAEGMKHVTMELGGKSPLIIFDDADIDNAVGGAINGNFYSSGQVCSNGTRVFVQKGIKEK
FLARLAERTGNAILGDPMDEATSFGPMVTENQMNIVLGYIEKGKEEGARLICGGRRADMD
GYFIEPTVFADVTDDMTIAREEIFGPVMSVLDFDTEEEVVARANDTEFGLSAGVFTKDFT
RAHRVIGNLEAGSCFINSYNDAPVEAPFGGVKASGVGRENSKEAIKHFSQVKSVYVRMGD
VEAAF
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Lawrence Berkeley National Laboratory