Comparing GFF2201 HP15_2155 triosephosphate isomerase to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4mvaA 1.43 angstrom resolution crystal structure of triosephosphate isomerase (tpia) from escherichia coli in complex with acetyl phosphate. (see paper)
43% identity, 96% coverage: 1:258/268 of query aligns to 1:252/255 of 4mvaA
B1XB85 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Escherichia coli (strain K12 / DH10B) (see paper)
43% identity, 96% coverage: 1:258/268 of query aligns to 1:252/255 of B1XB85
6neeB Crystal structure of a reconstructed ancestor of triosephosphate isomerase from eukaryotes (see paper)
44% identity, 94% coverage: 2:253/268 of query aligns to 4:250/252 of 6neeB
6ooiC Crystal structure of triosephosphate isomerase from schistosoma mansoni in complex with 2pg (see paper)
43% identity, 94% coverage: 2:253/268 of query aligns to 8:253/255 of 6ooiC
P36204 Bifunctional PGK/TIM; EC 2.7.2.3; EC 5.3.1.1 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
43% identity, 90% coverage: 2:243/268 of query aligns to 402:639/654 of P36204
Sites not aligning to the query:
P27876 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Bacillus subtilis (strain 168) (see paper)
40% identity, 92% coverage: 1:247/268 of query aligns to 1:243/253 of P27876
4y96A Crystal structure of triosephosphate isomerase from gemmata obscuriglobus (see paper)
44% identity, 94% coverage: 2:253/268 of query aligns to 2:248/250 of 4y96A
P00942 Triosephosphate isomerase; TIM; Triose-phosphate isomerase; EC 5.3.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
42% identity, 88% coverage: 8:243/268 of query aligns to 9:237/248 of P00942
Sites not aligning to the query:
3uwzA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with glycerol-2-phosphate (see paper)
39% identity, 92% coverage: 1:247/268 of query aligns to 2:246/254 of 3uwzA
3uwwA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with 3-phosphoglyceric acid (see paper)
39% identity, 92% coverage: 1:247/268 of query aligns to 2:246/254 of 3uwwA
3uwuA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with glycerol-3-phosphate (see paper)
39% identity, 92% coverage: 1:247/268 of query aligns to 1:245/253 of 3uwuA
Q6GIL6 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Staphylococcus aureus (strain MRSA252) (see paper)
39% identity, 92% coverage: 1:247/268 of query aligns to 1:245/253 of Q6GIL6
3uwvA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with 2-phosphoglyceric acid (see paper)
39% identity, 92% coverage: 1:247/268 of query aligns to 3:247/255 of 3uwvA
P50921 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Moritella marina (Vibrio marinus) (see paper)
41% identity, 90% coverage: 1:242/268 of query aligns to 1:239/256 of P50921
A0A1L5YRA2 Triosephosphate isomerase; TIM; Allergen Scy p 8; Methylglyoxal synthase; Triose-phosphate isomerase; Allergen Scy p 8.0101; EC 5.3.1.1; EC 4.2.3.3 from Scylla paramamosain (Mud crab) (see paper)
41% identity, 95% coverage: 2:255/268 of query aligns to 5:248/248 of A0A1L5YRA2
P07669 Triosephosphate isomerase; TIM; Triose-phosphate isomerase; EC 5.3.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
44% identity, 93% coverage: 2:250/268 of query aligns to 3:243/249 of P07669
5zfxB Crystal structure of triosephosphate isomerase from opisthorchis viverrini (see paper)
42% identity, 91% coverage: 2:245/268 of query aligns to 1:239/248 of 5zfxB
3ypiA Electrophilic catalysis in triosephosphase isomerase: the role of histidine-95 (see paper)
42% identity, 88% coverage: 8:243/268 of query aligns to 8:236/247 of 3ypiA
1aw1A Triosephosphate isomerase of vibrio marinus complexed with 2- phosphoglycolate (see paper)
41% identity, 90% coverage: 2:242/268 of query aligns to 1:238/255 of 1aw1A
4ff7B Structure of c126s mutant of saccharomyces cerevisiae triosephosphate isomerase (see paper)
42% identity, 88% coverage: 8:243/268 of query aligns to 8:236/247 of 4ff7B
>GFF2201 HP15_2155 triosephosphate isomerase
MRKPILIGNWKMNGSLQANQALMVRVLPRLRMFRKSVDLVVCPPHPYLFQVRDLLGYTGI
MLGAQNASGFVSGAYTGEVSATMLQEMGCRYALVGHSERRLLFGEGNQEVAARYRSVLQS
GLTPVLCVGETLEDRESGRTGLIIEQQLQAVIDEVGLAAMANGIVAYEPVWAIGTGKTAT
PEQVSEVHQQIRQFLAKSAPESADDISEELRVIYGGSVKVANAYELFSLADVDGGLIGGA
SLHADEFGTIAGALAEASGILAGECETH
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Lawrence Berkeley National Laboratory