Comparing GFF2246 HP15_2196 glutamate/glutamine/aspartate/asparagine ABC transporter, periplasmic substrate-binding protein to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 18 hits to proteins with known functional sites (download)
4z9nB Abc transporter / periplasmic binding protein from brucella ovis with glutathione bound
57% identity, 91% coverage: 32:347/347 of query aligns to 5:324/324 of 4z9nB
4zv1A An ancestral arginine-binding protein bound to arginine (see paper)
28% identity, 61% coverage: 41:253/347 of query aligns to 3:208/226 of 4zv1A
4zv2A An ancestral arginine-binding protein bound to glutamine (see paper)
29% identity, 61% coverage: 41:253/347 of query aligns to 3:206/225 of 4zv2A
5t0wA Crystal structure of the ancestral amino acid-binding protein anccdt- 1, a precursor of cyclohexadienyl dehydratase
27% identity, 63% coverage: 33:249/347 of query aligns to 1:207/229 of 5t0wA
1xt8B Crystal structure of cysteine-binding protein from campylobacter jejuni at 2.0 a resolution (see paper)
26% identity, 61% coverage: 33:244/347 of query aligns to 5:208/251 of 1xt8B
2yjpA Crystal structure of the solute receptors for l-cysteine of neisseria gonorrhoeae (see paper)
28% identity, 64% coverage: 32:252/347 of query aligns to 1:210/247 of 2yjpA
2v25A Structure of the campylobacter jejuni antigen peb1a, an aspartate and glutamate receptor with bound aspartate (see paper)
27% identity, 60% coverage: 35:242/347 of query aligns to 3:204/231 of 2v25A
5eyfB Crystal structure of solute-binding protein from enterococcus faecium with bound glutamate
25% identity, 63% coverage: 35:253/347 of query aligns to 6:217/243 of 5eyfB
2ia4B Crystal structure of novel amino acid binding protein from shigella flexneri
25% identity, 62% coverage: 31:245/347 of query aligns to 5:221/278 of 2ia4B
6h2tA Glnh bound to glu, mycobacterium tuberculosis (see paper)
33% identity, 40% coverage: 26:164/347 of query aligns to 36:173/288 of 6h2tA
Sites not aligning to the query:
6h20A Glnh bound to asn, mycobacterium tuberculosis (see paper)
33% identity, 40% coverage: 26:164/347 of query aligns to 35:172/287 of 6h20A
Sites not aligning to the query:
6h1uA Glnh bound to asp, mycobacterium tuberculosis (see paper)
33% identity, 40% coverage: 26:164/347 of query aligns to 35:172/287 of 6h1uA
Sites not aligning to the query:
3k4uE Crystal structure of putative binding component of abc transporter from wolinella succinogenes dsm 1740 complexed with lysine
25% identity, 63% coverage: 41:260/347 of query aligns to 3:215/234 of 3k4uE
6svfA Crystal structure of the p235gk mutant of argbp from t. Maritima (see paper)
26% identity, 63% coverage: 35:253/347 of query aligns to 3:210/229 of 6svfA
3vvfA Crystal structure of ttc0807 complexed with arginine (see paper)
23% identity, 50% coverage: 34:206/347 of query aligns to 9:171/241 of 3vvfA
Sites not aligning to the query:
3vveA Crystal structure of ttc0807 complexed with lysine (see paper)
23% identity, 50% coverage: 34:206/347 of query aligns to 9:171/241 of 3vveA
Sites not aligning to the query:
3vvdA Crystal structure of ttc0807 complexed with ornithine (see paper)
23% identity, 50% coverage: 34:206/347 of query aligns to 9:171/241 of 3vvdA
Sites not aligning to the query:
3vv5A Crystal structure of ttc0807 complexed with (s)-2-aminoethyl-l- cysteine (aec) (see paper)
23% identity, 50% coverage: 34:206/347 of query aligns to 5:167/237 of 3vv5A
Sites not aligning to the query:
>GFF2246 HP15_2196 glutamate/glutamine/aspartate/asparagine ABC transporter, periplasmic substrate-binding protein
MFGEKTMRKTKSIALGIALAVGTFSATGAMAATTLENVKEKGHLQCGVTSGLPGFSQPDE
KGNWTGIDVDTCRAVAAAIFGDANAVEFTPLTAKERFTALQSGEIDMLSRNTTWTLTRDA
SLGLNFAGVNYYDGQGFLINKGIGVDDATQLDGATICIQAGTTTELNLSDYFRAKGMEFK
PIVFDTSEQTVQGFAAGRCDVLTSDRSQLAALRSKLSDPSSAKILPNTISKEPLGPVVRQ
GDDQWFNIVKWVLFAQINAEELGVTSANADDMLKSDNPNIQRLLGTDGDMGAKLGLPDDF
GYQAVKLVGNYGEMYDRNVGPDTPLGLDRGINALWTEGGIMYAPPVR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory