Comparing GFF2341 FitnessBrowser__WCS417:GFF2341 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 11 hits to proteins with known functional sites (download)
7yleA Rndmpx in complex with dmsp (see paper)
26% identity, 90% coverage: 31:335/338 of query aligns to 5:296/299 of 7yleA
Q5LT66 Trimethylamine N-oxide-binding protein; TMAO-binding protein from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) (see paper)
23% identity, 96% coverage: 1:325/338 of query aligns to 18:331/333 of Q5LT66
Sites not aligning to the query:
Q4FL33 Trimethylamine N-oxide-binding protein; TMAO-binding protein from Pelagibacter ubique (strain HTCC1062) (see paper)
25% identity, 95% coverage: 1:321/338 of query aligns to 1:309/314 of Q4FL33
4xz6A Tmox in complex with tmao (see paper)
24% identity, 88% coverage: 30:325/338 of query aligns to 9:289/291 of 4xz6A
1r9qA Structure analysis of prox in complex with proline betaine (see paper)
23% identity, 77% coverage: 72:332/338 of query aligns to 51:308/309 of 1r9qA
Sites not aligning to the query:
P0AFM2 Glycine betaine/proline betaine-binding periplasmic protein; GBBP from Escherichia coli (strain K12) (see 2 papers)
23% identity, 77% coverage: 72:332/338 of query aligns to 72:329/330 of P0AFM2
Sites not aligning to the query:
2rinA Abc-transporter choline binding protein in complex with acetylcholine (see paper)
21% identity, 37% coverage: 201:326/338 of query aligns to 158:268/288 of 2rinA
Sites not aligning to the query:
2regA Abc-transporter choline binding protein in complex with choline (see paper)
21% identity, 37% coverage: 201:326/338 of query aligns to 160:270/290 of 2regA
Sites not aligning to the query:
5nxxC Crystal structure of opuac from b. Subtilis in complex with arsenobetaine (see paper)
23% identity, 43% coverage: 179:324/338 of query aligns to 28:152/265 of 5nxxC
Sites not aligning to the query:
2b4mA Crystal structure of the binding protein opuac in complex with proline betaine (see paper)
23% identity, 43% coverage: 179:324/338 of query aligns to 27:151/264 of 2b4mA
Sites not aligning to the query:
3chgA The compatible solute-binding protein opuac from bacillus subtilis in complex with dmsa (see paper)
23% identity, 43% coverage: 179:324/338 of query aligns to 21:145/258 of 3chgA
Sites not aligning to the query:
>GFF2341 FitnessBrowser__WCS417:GFF2341
MKGLKTLLAASLTTLGLSVAALPVSAAEAPVHFADLNWESGSLITEVLRVIVEKGYDLPT
DTLPGTTITLETALAKNDIQVIGEEWAGRSPVWVKAEAEGKVVGLGDTVKGATEGWWVPE
YVVKGDPAKGIKPLAPELKSVKDLARYKDVFKDPESPGKGRFLNSPIGWTSEVVNKQKLK
AYGLDDSYVNFRSGSGAALDAEIASSIRRGKPVLFYYWSPTPLMGRYKLIQLEEPPFDAE
AWKTLTDADNPNPKPTRSLASKLSIGVSTPFQKEHPQIAQFFEKVEFPIEPLNKALATMS
ENHTAPREVAQMFLKEHPQVWKAWLTEDVAQKVEASLK
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory