Comparing GFF2391 FitnessBrowser__WCS417:GFF2391 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
P0AAH4 Putrescine export system ATP-binding protein SapD from Escherichia coli (strain K12) (see paper)
39% identity, 49% coverage: 6:267/531 of query aligns to 3:268/330 of P0AAH4
7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp (see paper)
38% identity, 48% coverage: 274:529/531 of query aligns to 2:248/250 of 7z18I
7z15I E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
38% identity, 48% coverage: 274:529/531 of query aligns to 2:248/253 of 7z15I
7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation (see paper)
38% identity, 48% coverage: 274:529/531 of query aligns to 2:248/250 of 7z16I
4fwiB Crystal structure of the nucleotide-binding domain of a dipeptide abc transporter (see paper)
35% identity, 51% coverage: 6:274/531 of query aligns to 3:271/310 of 4fwiB
Sites not aligning to the query:
Q8RDH4 Dipeptide transport ATP-binding protein DppD; EC 7.4.2.9 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
36% identity, 48% coverage: 6:258/531 of query aligns to 4:255/326 of Q8RDH4
Sites not aligning to the query:
P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 3 papers)
33% identity, 44% coverage: 299:529/531 of query aligns to 18:245/343 of P30750
Sites not aligning to the query:
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form (see paper)
33% identity, 44% coverage: 299:529/531 of query aligns to 19:246/344 of 3tuzC
Sites not aligning to the query:
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form (see paper)
33% identity, 44% coverage: 299:529/531 of query aligns to 19:246/344 of 3tuiC
Sites not aligning to the query:
6cvlD Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
33% identity, 44% coverage: 299:529/531 of query aligns to 19:246/344 of 6cvlD
Sites not aligning to the query:
4u00A Crystal structure of ttha1159 in complex with adp (see paper)
34% identity, 48% coverage: 274:526/531 of query aligns to 1:237/241 of 4u00A
P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 3 papers)
36% identity, 43% coverage: 292:520/531 of query aligns to 23:243/378 of P69874
Sites not aligning to the query:
3c4jA Abc protein artp in complex with atp-gamma-s
32% identity, 45% coverage: 292:529/531 of query aligns to 9:242/242 of 3c4jA
3c41J Abc protein artp in complex with amp-pnp/mg2+
32% identity, 45% coverage: 292:529/531 of query aligns to 9:242/242 of 3c41J
2olkA Abc protein artp in complex with adp-beta-s
32% identity, 45% coverage: 292:529/531 of query aligns to 9:242/242 of 2olkA
2oljA Abc protein artp in complex with adp/mg2+
32% identity, 45% coverage: 292:529/531 of query aligns to 9:242/242 of 2oljA
7ahhC Opua inhibited inward-facing, sbd docked (see paper)
34% identity, 42% coverage: 306:526/531 of query aligns to 46:264/382 of 7ahhC
Sites not aligning to the query:
7aheC Opua inhibited inward facing (see paper)
34% identity, 42% coverage: 306:526/531 of query aligns to 46:264/382 of 7aheC
Sites not aligning to the query:
P75957 Lipoprotein-releasing system ATP-binding protein LolD; EC 7.6.2.- from Escherichia coli (strain K12) (see paper)
38% identity, 42% coverage: 275:495/531 of query aligns to 5:216/233 of P75957
7mdyC Lolcde nucleotide-bound
38% identity, 42% coverage: 275:495/531 of query aligns to 2:213/226 of 7mdyC
>GFF2391 FitnessBrowser__WCS417:GFF2391
MNQDNLIEIRDLSVEFVTGDHHHRVVNNVSFDIKRGETIALVGESGSGKSVTAHSILRLL
PYPLARHPSGTINYAGQDLLTLKEKTIRHIRGNRIAMIFQEPMTSLNPLHSIEKQINEVL
GLHKGLQGKVATQRTLELLDLVGIPEPHKRLKALPHELSGGQRQRVMIAMALANEPELLI
ADEPTTALDVTVQLKILELLKELQARLGMALLLISHDLNLVRRIAHRVCVMQKGCIVEQA
DCETLFQSPQHPYTQELLAAEPSGGPASNAIGPPLLEVDNLKVWFPIKKGFLRNTVDYVK
AVDGINFSLPQGQTLGIVGESGSGKSTLGLAILRLIASKGGIRFEGQQLDTLSQQQVRPL
RREMQVVFQDPFGSLSPRMCVSEIVGEGLRIHKMGTPAEQEAAIIAALKEVGLDPESRHR
YPHEFSGGQRQRIAIARALVLKPRLILLDEPTSALDRTVQRQVVELLRSLQTKYNLTYLF
ISHDLAVVKALSHQLMVVKHGQVVEQGDAAEIFAAPQHGYTRQLLEAAFLV
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory