Comparing GFF2543 FitnessBrowser__WCS417:GFF2543 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
5z0qC Crystal structure of ovob (see paper)
44% identity, 98% coverage: 3:378/383 of query aligns to 1:375/379 of 5z0qC
4dq6A Crystal structure of plp-bound putative aminotransferase from clostridium difficile 630
32% identity, 99% coverage: 1:378/383 of query aligns to 1:387/388 of 4dq6A
6qp3A Crystal structure of the plp-bound c-s lyase from bacillus subtilis (strain 168) (see paper)
36% identity, 98% coverage: 3:378/383 of query aligns to 1:386/387 of 6qp3A
1c7oA Crystal structure of cystalysin from treponema denticola contains a pyridoxal 5'-phosphate-l-aminoethoxyvinylglycine complex (see paper)
30% identity, 99% coverage: 1:380/383 of query aligns to 1:392/394 of 1c7oA
1c7nA Crystal structure of cystalysin from treponema denticola contains a pyridoxal 5'-phosphate cofactor (see paper)
30% identity, 99% coverage: 1:380/383 of query aligns to 1:392/394 of 1c7nA
6qp1B Crystal structure of the plp-bound c-s lyase in the external aldimine form from staphylococcus hominis complexed with an inhibitor, l- cycloserine. (see paper)
32% identity, 96% coverage: 12:378/383 of query aligns to 32:397/398 of 6qp1B
3b1eA Crystal structure of betac-s lyase from streptococcus anginosus in complex with l-serine: alpha-aminoacrylate form (see paper)
32% identity, 97% coverage: 2:374/383 of query aligns to 2:381/387 of 3b1eA
3b1dA Crystal structure of betac-s lyase from streptococcus anginosus in complex with l-serine: external aldimine form (see paper)
32% identity, 97% coverage: 2:374/383 of query aligns to 2:381/387 of 3b1dA
3b1cA Crystal structure of betac-s lyase from streptococcus anginosus: internal aldimine form (see paper)
32% identity, 97% coverage: 2:374/383 of query aligns to 2:381/387 of 3b1cA
6qp2A Crystal structure of the plp-bound c-s lyase from staphylococcus hominis (see paper)
32% identity, 98% coverage: 3:378/383 of query aligns to 1:378/383 of 6qp2A
3l8aB Crystal structure of metc from streptococcus mutans
31% identity, 97% coverage: 3:374/383 of query aligns to 2:379/385 of 3l8aB
8bobA Structural basis for negative regulation of the maltose system (see paper)
33% identity, 98% coverage: 3:379/383 of query aligns to 2:387/390 of 8bobA
P23256 Protein MalY; EC 4.4.1.13 from Escherichia coli (strain K12) (see 2 papers)
33% identity, 98% coverage: 3:379/383 of query aligns to 2:387/390 of P23256
7qugA Crystal structure of carbon-sulfur lyase fnapatb1 from fusobacterium nucleatum subspecies animalis in complex with allyl-cysteine (see paper)
30% identity, 93% coverage: 24:381/383 of query aligns to 39:397/397 of 7qugA
Sites not aligning to the query:
1gdeA Crystal structure of pyrococcus protein a-1 e-form (see paper)
27% identity, 94% coverage: 24:382/383 of query aligns to 25:386/388 of 1gdeA
1gd9A Crystall structure of pyrococcus protein-a1 (see paper)
27% identity, 94% coverage: 24:382/383 of query aligns to 25:386/388 of 1gd9A
1j32A Aspartate aminotransferase from phormidium lapideum
26% identity, 93% coverage: 25:380/383 of query aligns to 31:386/388 of 1j32A
2o0rA The three-dimensional structure of n-succinyldiaminopimelate aminotransferase from mycobacterium tuberculosis (see paper)
29% identity, 78% coverage: 76:375/383 of query aligns to 78:381/385 of 2o0rA
Sites not aligning to the query:
5yhvB Crystal structure of an aminotransferase from mycobacterium tuberculosis
27% identity, 84% coverage: 55:374/383 of query aligns to 61:380/387 of 5yhvB
5yhvA Crystal structure of an aminotransferase from mycobacterium tuberculosis
27% identity, 84% coverage: 55:374/383 of query aligns to 68:387/394 of 5yhvA
>GFF2543 FitnessBrowser__WCS417:GFF2543
MSFDFDTIHPRFGTGSTKWSRYPQDVLPMWIADMDIAAPPAVLQALHARIDQQVLGYSVA
GPDVREAIIADLWAKYGWRVQPDELLFLPGVEPGFNMALHAFVQPGQPVVLQTPNYRPIR
LAPGHWNLPRIEVPFEQVNGEYLTPMPAMRQALTGAGALLLSNPHNPMGKVFPREELLAV
ANACLENGALIISDEIHAELCFDGRRHIPTASLSPEIAQRTITLMSASKAYNVAGLKTCF
AVIQNAEIRERFNNARCGMVDSVSPLGLEATRAAYSQCNDWLDALVQYLQSNRDYLLDAV
QTRLPGVVMHAPQGTYLAWLDCSALGLDDPQQFFLEQAKVGLSAGIEFGDDSQQFVRLNF
GCPRSMLEEGLQRMERALRNRQA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory