Comparing GFF2603 FitnessBrowser__psRCH2:GFF2603 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2d3tC Fatty acid beta-oxidation multienzyme complex from pseudomonas fragi, form v (see paper)
89% identity, 100% coverage: 2:391/391 of query aligns to 1:390/390 of 2d3tC
8oqlC Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-1
39% identity, 98% coverage: 7:391/391 of query aligns to 3:397/397 of 8oqlC
8gqmA Crystal structure of thiolase complexed with acetyl coenzyme a
41% identity, 98% coverage: 9:391/391 of query aligns to 4:375/377 of 8gqmA
8opuC Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with sulfamethoxazole (fragment-b-e1)
39% identity, 98% coverage: 7:391/391 of query aligns to 3:399/399 of 8opuC
8oqoC Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-49
39% identity, 98% coverage: 7:391/391 of query aligns to 3:398/398 of 8oqoC
8opyD Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-b-dnq
39% identity, 98% coverage: 7:391/391 of query aligns to 4:401/401 of 8opyD
8oqmD Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-10
39% identity, 98% coverage: 7:391/391 of query aligns to 4:399/399 of 8oqmD
8pf8C Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-72
39% identity, 98% coverage: 7:391/391 of query aligns to 3:402/402 of 8pf8C
8oqsC Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-83
39% identity, 98% coverage: 7:391/391 of query aligns to 3:402/402 of 8oqsC
8oqpC Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-76
39% identity, 98% coverage: 7:391/391 of query aligns to 3:402/402 of 8oqpC
4b3iC Crystal structure of mycobacterium tuberculosis fatty acid beta- oxidation complex with coenzymea bound at the hydratase active sites (see paper)
39% identity, 98% coverage: 7:391/391 of query aligns to 3:402/402 of 4b3iC
7o4tD Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme with coenzyme a bound at the hydratase, thiolase active sites and possible additional binding site (coa(ech/had)) (see paper)
39% identity, 98% coverage: 7:391/391 of query aligns to 4:403/403 of 7o4tD
O53871 Putative acyltransferase Rv0859; EC 2.3.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
39% identity, 98% coverage: 7:391/391 of query aligns to 4:403/403 of O53871
8opxC Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with trehalose (fragment-b-tre)
39% identity, 98% coverage: 7:391/391 of query aligns to 3:398/398 of 8opxC
P45359 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; CaTHL; EC 2.3.1.9 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / IAM 19013 / LMG 5710 / NBRC 13948 / NRRL B-527 / VKM B-1787 / 2291 / W) (see paper)
40% identity, 98% coverage: 6:390/391 of query aligns to 2:391/392 of P45359
4xl4A Crystal structure of thiolase from clostridium acetobutylicum in complex with coa (see paper)
40% identity, 98% coverage: 6:390/391 of query aligns to 2:391/392 of 4xl4A
6pccA Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a (see paper)
39% identity, 98% coverage: 7:391/391 of query aligns to 6:403/403 of 6pccA
6pcbA Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex with coa (see paper)
39% identity, 98% coverage: 7:391/391 of query aligns to 6:403/403 of 6pcbA
5f38D X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution (see paper)
42% identity, 98% coverage: 6:390/391 of query aligns to 4:394/394 of 5f38D
5f38B X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution (see paper)
42% identity, 99% coverage: 6:391/391 of query aligns to 2:391/391 of 5f38B
>GFF2603 FitnessBrowser__psRCH2:GFF2603
MSLNPRDAVIVDFGRTPMGRSKGGMHRNTRAETMSAHLIDGVLARNPKIDPAEVEDVIWG
CVNQTLEQGWNIARMASLMTRIPHTSAGQTVSRLCGSSMSALHTAVQAIQTNNGDVFVIG
GVEHMGHVSMMHGVDPNPQLSLYAAKASGMMGLTAEMLGKMHGITREQQDAFGERSHRLA
HKATLEGNFKDEIIPMEGYDEDGFLKVFDYDETIRPDTTLESLAALKPAFNPKGGTVTAG
TSSQITDGASCMIVMSAQRAKDLGIQPLAVVRAMALAGVDPAIMGYGPVPSTQKVLKRAG
LTMDDISHVELNEAFAAQALPVLKDLKLLDKMEEKVNLHGGAIALGHPFGCSGARISGTL
LNVMKQNNGTIGVATMCIGLGQGISTVFERV
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory