Comparing GFF2721 FitnessBrowser__psRCH2:GFF2721 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 7 hits to proteins with known functional sites (download)
2r46A Crystal structure of escherichia coli glycerol-3-phosphate dehydrogenase in complex with 2-phosphopyruvic acid. (see paper)
58% identity, 91% coverage: 35:498/511 of query aligns to 27:491/495 of 2r46A
Sites not aligning to the query:
2r45A Crystal structure of escherichia coli glycerol-3-phosphate dehydrogenase in complex with 2-phospho-d-glyceric acid (see paper)
58% identity, 91% coverage: 35:498/511 of query aligns to 27:491/495 of 2r45A
Sites not aligning to the query:
2qcuB Crystal structure of glycerol-3-phosphate dehydrogenase from escherichia coli (see paper)
58% identity, 91% coverage: 35:498/511 of query aligns to 27:491/501 of 2qcuB
Sites not aligning to the query:
Q9SS48 Glycerol-3-phosphate dehydrogenase SDP6, mitochondrial; Protein SUGAR-DEPENDENT 6; EC 1.1.5.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
31% identity, 94% coverage: 5:482/511 of query aligns to 67:573/629 of Q9SS48
2rgoA Structure of alpha-glycerophosphate oxidase from streptococcus sp.: A template for the mitochondrial alpha-glycerophosphate dehydrogenase (see paper)
29% identity, 87% coverage: 34:479/511 of query aligns to 41:505/557 of 2rgoA
Sites not aligning to the query:
2rgoB Structure of alpha-glycerophosphate oxidase from streptococcus sp.: A template for the mitochondrial alpha-glycerophosphate dehydrogenase (see paper)
31% identity, 67% coverage: 34:373/511 of query aligns to 39:386/530 of 2rgoB
Sites not aligning to the query:
3da1A X-ray structure of the glycerol-3-phosphate dehydrogenase from bacillus halodurans complexed with fad. Northeast structural genomics consortium target bhr167.
28% identity, 92% coverage: 29:498/511 of query aligns to 36:465/496 of 3da1A
Sites not aligning to the query:
>GFF2721 FitnessBrowser__psRCH2:GFF2721
MPHSAQPVSELYDVAVIGGGINGVGIAADAAGRGLSVFLCERDDLASHTSSASSKLIHGG
LRYLEHYEFRLVREALAEREMLLAKAPHIVKPMRFVLPHRPHLRPAWMIRAGLFLYDNLG
MRKKLPASRGLRFGSESPLKPVITRGFEYSDCWVDDARLVVLNAMAAREKGAHIHTRTQC
LSAKRAGGIWHVELQREDGSRFSLRAKALVNAAGPWVAQFIGENLQQRSPYGIRLIQGSH
IIVPKLYEGEQAYIMQNEDRRIVFAIPYLDRYTMIGTTDREYRGDPAKVSISEEEIAYVL
GVANTHFRKQLEPRDIVHTFAGVRPLCDDESDNPSAVTRDYTLSLAAEEKQAPLLSVFGG
KLTTYRKLAESAMAQLKPFFPAMGGSWTAQAALPGGEDMSTADALTEELVAKVQGLKLPL
AKRWATLYGNRVWRMLGEAHSLDALGEDLGQQLYAQEVEYLRREEWATQVDDILWRRTKL
GLAFSEPEKARLARYLAERPIAETARNSDAA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory