Comparing GFF2903 PS417_14855 gluconolactonase to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 19 hits to proteins with known functional sites (download)
3dr2A Structural and functional analyses of xc5397 from xanthomonas campestris: a gluconolactonase important in glucose secondary metabolic pathways (see paper)
35% identity, 81% coverage: 61:354/365 of query aligns to 25:296/299 of 3dr2A
3e5zA X-ray structure of the putative gluconolactonase in protein family pf08450. Northeast structural genomics consortium target drr130.
31% identity, 84% coverage: 53:359/365 of query aligns to 2:286/290 of 3e5zA
7pldB Caulobacter crescentus xylonolactonase with (r)-4-hydroxy-2- pyrrolidone (see paper)
29% identity, 73% coverage: 81:345/365 of query aligns to 17:250/289 of 7pldB
Sites not aligning to the query:
7plbB Caulobacter crescentus xylonolactonase with d-xylose (see paper)
29% identity, 73% coverage: 81:345/365 of query aligns to 17:250/289 of 7plbB
Sites not aligning to the query:
Q9A9Z1 D-xylonolactone lactonase; Xylono-1,5-lactonase; EC 3.1.1.110 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) (see paper)
29% identity, 73% coverage: 81:345/365 of query aligns to 17:250/289 of Q9A9Z1
8dk0A Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound (s)gamma- valerolactone (see paper)
25% identity, 74% coverage: 68:337/365 of query aligns to 1:260/293 of 8dk0A
8djzA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound product (see paper)
25% identity, 74% coverage: 68:337/365 of query aligns to 1:260/293 of 8djzA
8djfA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound tetrahedral intermediate (see paper)
25% identity, 74% coverage: 68:337/365 of query aligns to 1:260/293 of 8djfA
7risA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound phosphate (see paper)
26% identity, 73% coverage: 70:337/365 of query aligns to 1:260/293 of 7risA
2dsoC Crystal structure of d138n mutant of drp35, a 35kda drug responsive protein from staphylococcus aureus (see paper)
30% identity, 55% coverage: 129:329/365 of query aligns to 93:271/323 of 2dsoC
Sites not aligning to the query:
7rizA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound 2-hydroxyquinoline (see paper)
25% identity, 73% coverage: 70:337/365 of query aligns to 1:273/306 of 7rizA
Q99QV3 Lactonase drp35; EC 3.1.1.- from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see paper)
30% identity, 55% coverage: 129:329/365 of query aligns to 95:273/324 of Q99QV3
Sites not aligning to the query:
4gnaA Mouse smp30/gnl-xylitol complex (see paper)
25% identity, 75% coverage: 73:345/365 of query aligns to 8:258/297 of 4gnaA
4gn9A Mouse smp30/gnl-glucose complex (see paper)
25% identity, 75% coverage: 73:345/365 of query aligns to 8:258/297 of 4gn9A
4gn8A Mouse smp30/gnl-1,5-ag complex (see paper)
25% identity, 75% coverage: 73:345/365 of query aligns to 8:258/297 of 4gn8A
Sites not aligning to the query:
4gn7A Mouse smp30/gnl (see paper)
25% identity, 75% coverage: 73:345/365 of query aligns to 8:258/297 of 4gn7A
3g4hA Crystal structure of human senescence marker protein-30 (zinc bound) (see paper)
25% identity, 75% coverage: 73:345/365 of query aligns to 8:258/297 of 3g4hA
4gncA Human smp30/gnl-1,5-ag complex (see paper)
25% identity, 75% coverage: 73:345/365 of query aligns to 9:259/298 of 4gncA
Sites not aligning to the query:
Q15493 Regucalcin; RC; Gluconolactonase; GNL; Senescence marker protein 30; SMP-30; EC 3.1.1.17 from Homo sapiens (Human) (see 2 papers)
25% identity, 75% coverage: 73:345/365 of query aligns to 10:260/299 of Q15493
>GFF2903 PS417_14855 gluconolactonase
MDLPPLPTRTDHTRRVFLKRSLAVSASVAVLGNLPRLADAAEPLSQRYPDPLIKVLDDSF
LELRLFNASVERLATGLRWAEGPVWIGDGRYLLVSDIPNNRIVRWDEVTDSLSVYRENAN
FSNGMCRDRQGRLLVCEGSTTTREGRRITRTEHNGSLTVLADSFDGKPFNSPNDIVCKRD
GSVWFTDPPFQTSNNYEGHKIAPTQPHGVYRIDGESGTVTRVIDDLNGPNGLCFSPDEKV
LYVVEGRAKPNRLIWAIDVKDDGTLGARRKHIEGFDYAALDGIKCDESGNLWCGWGGNGD
PKADLEKLDGVRVFNPQGKAIGHISLPERCPNLCFGGREGNRLFMAGSHSIYSLFVNTRD
AGFGS
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Lawrence Berkeley National Laboratory