Comparing GFF3053 FitnessBrowser__Marino:GFF3053 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P07821 Iron(3+)-hydroxamate import ATP-binding protein FhuC; Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC; EC 7.2.2.16 from Escherichia coli (strain K12) (see 2 papers)
38% identity, 86% coverage: 2:236/273 of query aligns to 11:247/265 of P07821
4fi3C Structure of vitamin b12 transporter btucd-f in a nucleotide-bound state (see paper)
36% identity, 83% coverage: 25:251/273 of query aligns to 22:245/248 of 4fi3C
Sites not aligning to the query:
1l7vC Bacterial abc transporter involved in b12 uptake (see paper)
37% identity, 77% coverage: 27:236/273 of query aligns to 24:231/231 of 1l7vC
4ymuJ Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
31% identity, 82% coverage: 2:225/273 of query aligns to 1:224/240 of 4ymuJ
5x40A Structure of a cbio dimer bound with amppcp (see paper)
39% identity, 73% coverage: 28:226/273 of query aligns to 31:229/280 of 5x40A
Sites not aligning to the query:
4u00A Crystal structure of ttha1159 in complex with adp (see paper)
33% identity, 88% coverage: 2:241/273 of query aligns to 2:240/241 of 4u00A
3d31A Modbc from methanosarcina acetivorans (see paper)
31% identity, 83% coverage: 20:246/273 of query aligns to 18:244/348 of 3d31A
Sites not aligning to the query:
3c4jA Abc protein artp in complex with atp-gamma-s
29% identity, 88% coverage: 2:240/273 of query aligns to 3:241/242 of 3c4jA
3c41J Abc protein artp in complex with amp-pnp/mg2+
29% identity, 88% coverage: 2:240/273 of query aligns to 3:241/242 of 3c41J
2olkA Abc protein artp in complex with adp-beta-s
29% identity, 88% coverage: 2:240/273 of query aligns to 3:241/242 of 2olkA
2oljA Abc protein artp in complex with adp/mg2+
29% identity, 88% coverage: 2:240/273 of query aligns to 3:241/242 of 2oljA
6mjpA Lptb(e163q)fgc from vibrio cholerae (see paper)
28% identity, 85% coverage: 2:234/273 of query aligns to 2:233/240 of 6mjpA
7ahhC Opua inhibited inward-facing, sbd docked (see paper)
28% identity, 89% coverage: 18:260/273 of query aligns to 42:287/382 of 7ahhC
Sites not aligning to the query:
7aheC Opua inhibited inward facing (see paper)
28% identity, 89% coverage: 18:260/273 of query aligns to 42:287/382 of 7aheC
Sites not aligning to the query:
6b8bA E. Coli lptb in complex with adp and a novobiocin derivative (see paper)
29% identity, 85% coverage: 3:234/273 of query aligns to 3:233/233 of 6b8bA
6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide (see paper)
30% identity, 85% coverage: 3:234/273 of query aligns to 3:233/238 of 6s8nB
6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp (see paper)
30% identity, 85% coverage: 3:234/273 of query aligns to 3:233/238 of 6s8gA
6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter (see paper)
29% identity, 85% coverage: 3:234/273 of query aligns to 3:233/235 of 6mhzA
6b89A E. Coli lptb in complex with adp and novobiocin (see paper)
29% identity, 85% coverage: 3:234/273 of query aligns to 3:233/234 of 6b89A
4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium (see paper)
29% identity, 85% coverage: 3:234/273 of query aligns to 3:233/234 of 4p31A
>GFF3053 FitnessBrowser__Marino:GFF3053
MVLCINNVSVSLERSRIVHGIDCHLEAGEVLMLLGPNGAGKSTLLRAISGDLPYGGSVTL
SGQELGKWRPERLARQRAVMPQRVEVNFPLTVEEVVQLGRPGTARGGSDPTVDRLMEELD
IAHLRYRLVPGLSGGEQQRLQLARVLAQIIDSPGDRLLLLDECTAALDPAHQQLVLDLVR
RLAKAEGMAVLAVVHDLNLAAQFADRLLLMREGRLVHEGSAREVLTPELLETVYGFTARV
VELEEGYPMVVPARTGPSSAYTAPWNPSCRQAS
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory