Comparing GFF3169 FitnessBrowser__Phaeo:GFF3169 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 19 hits to proteins with known functional sites (download)
8sutA Crystal structure of yisk from bacillus subtilis in complex with reaction product 4-hydroxy-2-oxoglutaric acid (see paper)
39% identity, 78% coverage: 59:279/284 of query aligns to 80:301/303 of 8sutA
8skyB Crystal structure of yisk from bacillus subtilis in complex with oxalate (see paper)
39% identity, 78% coverage: 59:279/284 of query aligns to 79:300/303 of 8skyB
6j5xB Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
31% identity, 85% coverage: 37:277/284 of query aligns to 34:274/280 of 6j5xB
6j5xA Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
31% identity, 85% coverage: 37:277/284 of query aligns to 34:274/280 of 6j5xA
6iymA Fumarylacetoacetate hydrolase (eafah) from psychrophilic exiguobacterium antarcticum (see paper)
37% identity, 74% coverage: 71:280/284 of query aligns to 69:275/277 of 6iymA
3r6oA Crystal structure of a probable 2-hydroxyhepta-2,4-diene-1, 7- dioateisomerase from mycobacterium abscessus (see paper)
32% identity, 76% coverage: 67:283/284 of query aligns to 59:264/265 of 3r6oA
3qdfA Crystal structure of 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase from mycobacterium marinum (see paper)
35% identity, 74% coverage: 70:279/284 of query aligns to 61:247/252 of 3qdfA
6v77B Crystal structure of a putative hpce protein from mycobacterium smegmatis
31% identity, 73% coverage: 68:273/284 of query aligns to 67:269/279 of 6v77B
4dbhA Crystal structure of cg1458 with inhibitor (see paper)
32% identity, 74% coverage: 72:281/284 of query aligns to 63:268/269 of 4dbhA
8gstC Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Pyruvate bound-form) (see paper)
27% identity, 99% coverage: 2:281/284 of query aligns to 7:280/290 of 8gstC
8gsrA Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Apo-form) (see paper)
27% identity, 99% coverage: 2:281/284 of query aligns to 7:280/290 of 8gsrA
1gttA Crystal structure of hpce (see paper)
34% identity, 57% coverage: 87:248/284 of query aligns to 232:390/421 of 1gttA
6sbiA X-ray structure of murine fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate (see paper)
29% identity, 74% coverage: 71:280/284 of query aligns to 12:214/216 of 6sbiA
Q6P587 Acylpyruvase FAHD1, mitochondrial; Fumarylacetoacetate hydrolase domain-containing protein 1; FAH domain-containing protein 1; Oxaloacetate decarboxylase; OAA decarboxylase; YisK-like protein; EC 3.7.1.5; EC 4.1.1.112 from Homo sapiens (Human) (see 3 papers)
28% identity, 75% coverage: 71:283/284 of query aligns to 18:223/224 of Q6P587
6fogA X-ray structure of homo sapiens fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate at 1.94a resolution. (see paper)
28% identity, 75% coverage: 71:283/284 of query aligns to 13:218/218 of 6fogA
1nkqA Crystal structure of yeast ynq8, a fumarylacetoacetate hydrolase family protein
29% identity, 71% coverage: 67:269/284 of query aligns to 5:222/247 of 1nkqA
6j5yA Crystal structure of fumarylpyruvate hydrolase from pseudomonas aeruginosa in complex with mn2+ and pyruvate (see paper)
31% identity, 66% coverage: 64:251/284 of query aligns to 18:209/233 of 6j5yA
6jvwB Crystal structure of maleylpyruvate hydrolase from sphingobium sp. Syk-6 in complex with manganese (ii) ion and pyruvate (see paper)
30% identity, 66% coverage: 67:254/284 of query aligns to 62:242/264 of 6jvwB
3v77A Crystal structure of a putative fumarylacetoacetate isomerase/hydrolase from oleispira antarctica (see paper)
26% identity, 63% coverage: 72:250/284 of query aligns to 17:197/224 of 3v77A
>GFF3169 FitnessBrowser__Phaeo:GFF3169
MKFASYSAAGQAFYGAATDDGMIALSPDFPQWPTLLDVVRAGGLDQLIVTAESRSVTHTD
VQYDMVLPNARRILCVGVNFPDRNAEYKDGSEQPKYMSLFPRFASGFTGHNRPLIRPPES
HMLDYEGEVAIVIGKGGRRIAQADAYDHIAALTICNEGTIRDWVRHAKFNVTQGKNWDNS
GAIGPWLVPFRDPAQLDDARITTRVNGDVRQDDVLSRMMHPIRREIEYISTFMTLEPGDI
IVTGTPTGSGARLDPPQFLKPGDVVEVEVTGIGILRNTIEDEQS
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory