Comparing GFF324 FitnessBrowser__WCS417:GFF324 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 5 hits to proteins with known functional sites (download)
P9WIB9 Secreted chorismate mutase; CM; *MtCM; EC 5.4.99.5 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
32% identity, 85% coverage: 23:174/178 of query aligns to 39:193/199 of P9WIB9
Sites not aligning to the query:
2ao2B The 2.07 angstrom crystal structure of mycobacterium tuberculosis chorismate mutase reveals unexpected gene duplication and suggests a role in host-pathogen interactions (see paper)
32% identity, 85% coverage: 23:174/178 of query aligns to 5:159/165 of 2ao2B
2ao2A The 2.07 angstrom crystal structure of mycobacterium tuberculosis chorismate mutase reveals unexpected gene duplication and suggests a role in host-pathogen interactions (see paper)
32% identity, 85% coverage: 23:174/178 of query aligns to 5:159/165 of 2ao2A
2fp2B Secreted chorismate mutase from mycobacterium tuberculosis (see paper)
32% identity, 85% coverage: 23:174/178 of query aligns to 3:157/163 of 2fp2B
Q7CHH5 Secreted chorismate mutase; CM; *YpCM; EC 5.4.99.5 from Yersinia pestis (see paper)
34% identity, 62% coverage: 25:135/178 of query aligns to 38:143/186 of Q7CHH5
Sites not aligning to the query:
>GFF324 FitnessBrowser__WCS417:GFF324
MKRRLVFALLFVSTSASAAPPTLEPLLNSIAERLEIADQVALSKWDSKKPVEDKKREQEV
IASVSAQAPTYKLDAAAAEQFFSAQIEANKLVQYTHLSDWQFQGKAPDDPRPDLIKQIRP
QLDELQKRLLQQLADFTPQRTDPQCPQWLAEAVHEPLNDPLRQLAMIRATAELCVRPT
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory